Posted on 10/07/2019 9:19:40 AM PDT by SeekAndFind
The Nobel Prize in Physiology or Medicine was jointly awarded to three scientists — William G. Kaelin Jr., Peter J. Ratcliffe and Gregg L. Semenza — for their work on how cells sense and adapt to oxygen availability.
The Nobel Assembly announced the prize at the Karolinska Institute in Stockholm on Monday.
Their work established the genetic mechanisms that allow cells to respond to changes in oxygen levels. The findings have implications for treating a variety of diseases, including cancer, anemia, heart attacks and strokes.
“Oxygen is the lifeblood of living organisms,” said Dr. George Daley, dean of Harvard Medical School. “Without oxygen, cells can’t survive.” But too much or too little oxygen also can be deadly. The three researchers tried to answer this question: How do cells regulate their responses?
The investigators uncovered detailed genetic responses to changing oxygen levels that allow cells in the bodies of humans and other animals sense and respond to fluctuations, increasing and decreasing how much oxygen they receive.
Why is the work important?
The discoveries reveal the cellular mechanisms that control such things as adaptation to high altitudes and how cancer cells manage to hijack oxygen. Randall Johnson, a member of the Nobel Assembly, described the work as a “textbook discovery” and said it would be something students would start learning at the most basic levels of biology education.
(Excerpt) Read more at nytimes.com ...
ABOUT THE WINNERS:
William G. Kaelin Jr., professor of medicine at Dana-Farber Cancer Institute and Brigham & Women’s Hospital Harvard Medical School
Gregg L. Semenza, professor of genetic medicine at Johns Hopkins, said his life was changed by a high school teacher, Rose Nelson, who taught biology at Sleepy Hollow High School in Tarrytown, N.Y.
Peter J. Ratcliffe, the third Nobelist, is the director of clinical research at the Francis Crick Institute in London and director of the Target Discovery Institute at Oxford.
Oxygen? WTH? I thought O2 had been mostly replaced by ‘See Uh Oh 2’. What gives? Does greta know about this? :-)
Funny how America and Britain, despite not being in a political union, can collaborate on scientific and medical projects yet leaving the EU will destroy such collaboration with other European countries...
Any from a m*slim country? just asking.
RE: Any from a m*slim country?
Are you referring to the UK? There’s lots of m*slims there.
Maybe this will support Hydrogen Peroxide Cancer Treatment.
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