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Biotech Company ReNeuron says stem cells improved motor function in stroke study
Reuters ^ | 12/05/2016

Posted on 12/05/2016 8:41:10 PM PST by SeekAndFind

Biotechnology company ReNeuron Group Plc said its experimental stem cell therapy helped some patients improve motor functions in their arms in a mid-stage study after being disabled by stroke.

Shares of the company jumped 22 percent to 3.45 pence per share in morning trade on Monday on the London Stock Exchange.

ReNueron's trial adds to a small but growing number of studies being conducted by a few publicly listed companies around the world that are testing stem cell therapies in various indications.

Stem cell therapy development has been stalled in the past by stricter regulations in United States, and concerns over side effects in testing a field that experts believe is still in its nascent stages.

U.S. stem cell therapy developer Asterias Biotherapeutics Inc said in November that an early study of its treatment for complete spinal cord injury hit its efficacy target within three months.

Fellow U.S. stem-cell therapy developer StemCells Inc merged with Israeli company Microbot Medical Ltd in August, a week after it scrapped a mid-stage study on its treatment for spinal cord injury.

ReNeuron said that 15 out of 21 patients that were treated with the company's CTX cell therapy showed statistically significant improvement on various scales in the study.

The company said that the data was encouraging despite the study failing to meet its main goal, as some of the responses to the treatment came after the study period of three months.

The British biotech firm had set the main goal of the mid-stage study as a two-point improvement in the motor function at three months after treatment, in two patients out of the 21 who have suffered a stroke and participated in the study.

ReNeuron said on Monday that three out of the 21 patients achieved improvement in their motor function

(Excerpt) Read more at reuters.com ...


TOPICS: Health/Medicine; Science
KEYWORDS: biotech; reneuron; stemcells; stroke

1 posted on 12/05/2016 8:41:10 PM PST by SeekAndFind
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To: SeekAndFind

I wonder if stem cell therapy could help with the severe post stroke pain some get due to wildly contracting muscles?

It would seem that those damaged cells causing the problem would still there, whereas giving movement back is essentially replacing dead cells.


2 posted on 12/05/2016 8:45:45 PM PST by dp0622 (IThe only thing an upper crust conservative hates more than a liberal is a middle class conservative)
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To: SeekAndFind

These are ADULT Stem Cells, NOT Embryonic Stem Cells.

There are three ways you can tell:

1-The results showed some medical potential. (ESCs NEVER do)
2-They didn’t mention the fact they used Adult Stem Cells, to leave the impression it “could be” ESCs showing positive results.
3-The story didn’t headline the NYT and the MSM for a month, which it would have if it were ESCs.


3 posted on 12/05/2016 9:36:30 PM PST by G Larry (America has the opportunity to return to God.)
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To: G Larry

I’m pretty sure ReNeuron uses fetal stem cells.


4 posted on 12/05/2016 10:06:54 PM PST by Theoria (I should never have surrendered. I should have fought until I was the last man alive)
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To: dp0622

My question would be would it help those like me with severe Peripheral Neuropathy due to pinched spinal nerves. All the seizure drugs they’ve tried have had such horrible side effects, the only one that doesn’t is Valium, and 20 mg is the limit the DEA allows, I need 30 mg for 24 hrs, and that only brings the level 9 pain down to level 4. My entire right side is effected and it grow worse as the disc in the spine continue to narrow, grow, spurs, protrusions, herniate, or bulge, I’ve 4 annular tears in those disc.

I know my crap Medicare/Tricare Life would not cover anything like this, they don’t even want to cover needed Lasik surgery to correct my botched vision. It is considered cosmetic.


5 posted on 12/06/2016 5:37:59 AM PST by GailA (Ret. SCPO wife: Merry CHRISTmas, Happy Birthday JESUS CHRIST, suck it up buttercup you lost)
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To: Theoria

Everything at this link “seems” to address adult stem cells.

>http://www.reneuron.com/products/products-technologies/#products<

I know that all prior work on Critical Limb Ischaemia at ASTM used adult stem cells and I believe they sold their cell replication technology to ReNeuron.


6 posted on 12/06/2016 6:52:58 AM PST by G Larry (America has the opportunity to return to God.)
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To: G Larry
They use fetal stem cells from terminated pregnancies.

Link

7 posted on 12/06/2016 9:31:10 AM PST by Theoria (I should never have surrendered. I should have fought until I was the last man alive)
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To: Theoria

Thanks!

Then we should sell the stock short. (anticipating decline)

Because those effects have never been sustained.
They last for 3 months and then revert to decline.


8 posted on 12/06/2016 10:15:34 AM PST by G Larry (America has the opportunity to return to God.)
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To: Theoria

This is a rather odd claim on their part:

“The Company’s human stem cell programmes use human foetal stem cells obtained from therapeutic terminations of pregnancy, not ESC’s ....”

How do they make the distinction between
“human foetal stem cells obtained from therapeutic terminations of pregnancy,”
and
“not ESC’s”??


9 posted on 12/06/2016 4:57:05 PM PST by G Larry (America has the opportunity to return to God.)
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