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WHO: Ebola virus disease Fact Sheet
WHO ^ | Updated September 2014 | WHO

Posted on 10/02/2014 10:00:12 AM PDT by Heartlander

Ebola virus disease

Fact sheet N°103
Updated September 2014


Key facts


Background

The Ebola virus causes an acute, serious illness which is often fatal if untreated. Ebola virus disease (EVD) first appeared in 1976 in 2 simultaneous outbreaks, one in Nzara, Sudan, and the other in Yambuku, Democratic Republic of Congo. The latter occurred in a village near the Ebola River, from which the disease takes its name.

The current outbreak in west Africa, (first cases notified in March 2014), is the largest and most complex Ebola outbreak since the Ebola virus was first discovered in 1976. There have been more cases and deaths in this outbreak than all others combined. It has also spread between countries starting in Guinea then spreading across land borders to Sierra Leone and Liberia, by air (1 traveller only) to Nigeria, and by land (1 traveller) to Senegal.

The most severely affected countries, Guinea, Sierra Leone and Liberia have very weak health systems, lacking human and infrastructural resources, having only recently emerged from long periods of conflict and instability. On August 8, the WHO Director-General declared this outbreak a Public Health Emergency of International Concern.

A separate, unrelated Ebola outbreak began in Boende, Equateur, an isolated part of the Democratic Republic of Congo.

The virus family Filoviridae includes 3 genera: Cuevavirus, Marburgvirus, and Ebolavirus. There are 5 species that have been identified: Zaire, Bundibugyo, Sudan, Reston and Taï Forest. The first 3, Bundibugyo ebolavirus, Zaire ebolavirus, and Sudan ebolavirus have been associated with large outbreaks in Africa. The virus causing the 2014 west African outbreak belongs to the Zaire species.

Transmission

It is thought that fruit bats of the Pteropodidae family are natural Ebola virus hosts. Ebola is introduced into the human population through close contact with the blood, secretions, organs or other bodily fluids of infected animals such as chimpanzees, gorillas, fruit bats, monkeys, forest antelope and porcupines found ill or dead or in the rainforest.

Ebola then spreads through human-to-human transmission via direct contact (through broken skin or mucous membranes) with the blood, secretions, organs or other bodily fluids of infected people, and with surfaces and materials (e.g. bedding, clothing) contaminated with these fluids.

Health-care workers have frequently been infected while treating patients with suspected or confirmed EVD. This has occurred through close contact with patients when infection control precautions are not strictly practiced.

Burial ceremonies in which mourners have direct contact with the body of the deceased person can also play a role in the transmission of Ebola.

People remain infectious as long as their blood and body fluids, including semen and breast milk, contain the virus. Men who have recovered from the disease can still transmit the virus through their semen for up to 7 weeks after recovery from illness.

Symptoms of Ebola virus disease

The incubation period, that is, the time interval from infection with the virus to onset of symptoms is 2 to 21 days. Humans are not infectious until they develop symptoms. First symptoms are the sudden onset of fever fatigue, muscle pain, headache and sore throat. This is followed by vomiting, diarrhoea, rash, symptoms of impaired kidney and liver function, and in some cases, both internal and external bleeding (e.g. oozing from the gums, blood in the stools). Laboratory findings include low white blood cell and platelet counts and elevated liver enzymes.

Diagnosis

It can be difficult to distinguish EVD from other infectious diseases such as malaria, typhoid fever and meningitis. Confirmation that symptoms are caused by Ebola virus infection are made using the following investigations:

Samples from patients are an extreme biohazard risk; laboratory testing on non-inactivated samples should be conducted under maximum biological containment conditions.

Treatment and vaccines

Supportive care-rehydration with oral or intravenous fluids- and treatment of specific symptoms, improves survival. There is as yet no proven treatment available for EVD. However, a range of potential treatments including blood products, immune therapies and drug therapies are currently being evaluated. No licensed vaccines are available yet, but 2 potential vaccines are undergoing human safety testing.

Prevention and control

Good outbreak control relies on applying a package of interventions, namely case management, surveillance and contact tracing, a good laboratory service, safe burials and social mobilisation. Community engagement is key to successfully controlling outbreaks. Raising awareness of risk factors for Ebola infection and protective measures that individuals can take is an effective way to reduce human transmission. Risk reduction messaging should focus on several factors:

Controlling infection in health-care settings:

Health-care workers should always take standard precautions when caring for patients, regardless of their presumed diagnosis. These include basic hand hygiene, respiratory hygiene, use of personal protective equipment (to block splashes or other contact with infected materials), safe injection practices and safe burial practices.

Health-care workers caring for patients with suspected or confirmed Ebola virus should apply extra infection control measures to prevent contact with the patient’s blood and body fluids and contaminated surfaces or materials such as clothing and bedding. When in close contact (within 1 metre) of patients with EBV, health-care workers should wear face protection (a face shield or a medical mask and goggles), a clean, non-sterile long-sleeved gown, and gloves (sterile gloves for some procedures).

Laboratory workers are also at risk. Samples taken from humans and animals for investigation of Ebola infection should be handled by trained staff and processed in suitably equipped laboratories.

WHO response

WHO aims to prevent Ebola outbreaks by maintaining surveillance for Ebola virus disease and supporting at-risk countries to developed preparedness plans. The document provides overall guidance for control of Ebola and Marburg virus outbreaks:

When an outbreak is detected WHO responds by supporting surveillance, community engagement, case management, laboratory services, contact tracing, infection control, logistical support and training and assistance with safe burial practices.

WHO has developed detailed advice on Ebola infection prevention and control:



TOPICS: Education; Science; Society
KEYWORDS: ebola; ebolafacts; ebolatreatment; evd; who
The Ebola designated website of the WHO
(http://www.who.int/csr/disease/ebola/en/),

Ebola related frequently asked questions, WHO, 8 August 2014
(http://www.who.int/csr/disease/ebola/faq-ebola/en/)

Updates on Ebola: WHO Global Alert and Response (GAR) Disease Outbreak News (DONs)
http://www.who.int/csr/don/en/

1 posted on 10/02/2014 10:00:12 AM PDT by Heartlander
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To: Heartlander

I got a better idea. It’s the same idea used when they find that rats are carrying infected fleas.

Can you guess what I refer to?


2 posted on 10/02/2014 10:12:07 AM PDT by Terry L Smith
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To: Heartlander
Stay informed of all disease 'outbreaks'.

GLOBAL INCIDENT MAP + scrolling list of recent incidents + breakdown by DISEASE including details of each incident.

P.S. Have an extra pair of underwear ready before viewing this map.

3 posted on 10/02/2014 10:17:03 AM PDT by UCANSEE2 (Lost my tagline on Flight MH370. Sorry for the inconvenience.)
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To: Heartlander

The CDC has changed their site to admit “we still do not know exactly how people are infected with Ebola.”


4 posted on 10/02/2014 10:29:04 AM PDT by bgill
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To: bgill

In their pamphlet the WHO says that ebola comes from animals in the rain forest. I thought the rain forest was this grand repository of wonderful yet-to-be-discovered medicines. It sounds like it is a repository of human-killing diseases. Burn down the brain forests before it is too late!!!!!


5 posted on 10/02/2014 10:33:07 AM PDT by hal ogen (First Amendment or Reeducation Camp?)
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To: UCANSEE2

Thanks for the link:

It appears that the U.S. has as many or more “Incidents” than the rest of the world combined.


6 posted on 10/02/2014 10:36:37 AM PDT by PoloSec ( Believe the Gospel: how that Christ died for our sins, was buried and rose again)
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To: bgill
From Pigs to Monkeys, Ebola Goes Airborne

Nov 21, 2012 | Jane Huston | Research & Policy –

http://healthmap.org/site/diseasedaily/article/pigs-monkeys-ebola-goes-airborne-112112#sthash.srRHtwa1.dpuf

The Ebola has a 21 days incubation period before the infested person show symptoms. The CDC maintains that a person infested with Ebola cannot transmit it until they show symptoms of the disease. How can they assure that the person cannot infest another person after 10, 15, or 19 days of being infested by the virus while still not showing symptoms of the virus? The CDC falsely assure the American people that it cannot be transmitted by air although studies in Canada seems to prove otherwise.

When news broke that the Ebola virus had resurfaced in Uganda, investigators in Canada were making headlines of their own with research indicating the deadly virus may spread between species, through the air. The team, comprised of researchers from the National Centre for Foreign Animal Disease, the University of Manitoba, and the Public Health Agency of Canada, observed transmission of Ebola from pigs to monkeys.

They first inoculated a number of piglets with the Zaire strain of the Ebola virus. Ebola-Zaire is the deadliest strain, with mortality rates up to 90 percent. The piglets were then placed in a room with four cynomolgus macaques, a species of monkey commonly used in laboratories. The animals were separated by wire cages to prevent direct contact between the species. Within a few days, the inoculated piglets showed clinical signs of infection indicative of Ebola infection.

In pigs, Ebola generally causes respiratory illness and increased temperature. Nine days after infection, all piglets appeared to have recovered from the disease. Within eight days of exposure, two of the four monkeys showed signs of Ebola infection. Four days later, the remaining two monkeys were sick too. It is possible that the first two monkeys infected the other two, but transmission between non-human primates has never before been observed in a lab setting.

While the study provided evidence that transmission of Ebola between species is possible, researchers still cannot say for certain how that transmission actually occurred. There are three likely candidates for the route of transmission: airborne, droplet, or fomites.

Airborne and droplet transmission both technically travel through the air to infect others; the difference lies in the size of the infective particles. Smaller droplets persist in the air longer and are able to travel farther- these droplets are truly “airborne.” Larger droplets can neither travel as far nor persist for very long.

What do these findings mean? First and foremost, Ebola is not suddenly an airborne disease.

Doctor Boards Atlanta Flight In HazMat Suit To Protest "Lying CDC"

Zero Hedge ^ | 10/2/14 | Tyler Durden

"If they're not lying, they are grossly incompetent," said Dr. Gil Mobley, a microbiologist and emergency trauma physician from Springfield, Mo. as he checked in and cleared Atlanta airport security wearing a mask, goggles, gloves, boots and a hooded white jumpsuit emblazoned on the back with the words, "CDC is lying!" As The Atlanta Journal-Constitution reports, Mobley says the CDC is "sugar-coating" the risk of the virus spreading in the United States.

7 posted on 10/02/2014 10:38:44 AM PDT by Dqban22
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To: Heartlander

Thanks for posting.


8 posted on 10/02/2014 11:13:49 AM PDT by FamiliarFace
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To: Heartlander
The first EVD outbreaks tht are known to Westerners occurred in remote villages in Central Africa,
9 posted on 10/02/2014 11:38:13 AM PDT by arthurus
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To: Dqban22; hal ogen

You might want to take a gander at the CDC’s update here: http://www.freerepublic.com/focus/f-news/3210088/posts


10 posted on 10/02/2014 11:47:34 AM PDT by bgill (CDC, "we still do not know exactly how people are infected with Ebola")
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bkmk


11 posted on 10/02/2014 1:55:51 PM PDT by AllAmericanGirl44
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