Weight Gain May Be Influenced By Fructose Consumption

Southern California Clinical and Translational Science Institute ^ | 13 JAN 2013 | NA

[neverdem]

Note: USC researcher Kathleen Page, MD, is an SC CTSI KL2 Alumnae. As part of the program, she recieved support and acquired skills needed to secure a subsequent K23 Career Training Award to continue this research.

Feeling hungry after drinking something sweet? It could have something to do with the type of sugar you consumed, according to research at Yale University led by SC CTSI K Scholar Kathleen Page, principal investigator and assistant professor of medicine at the USC Keck School of Medicine.

 

Kathleen Page

The research determined that fructose and glucose, the two forms of simple sugars, are processed differently in the brain. The difference was apparent after study participants consumed drinks containing fructose or glucose, and is a potential explanation for why we gain weight.

“We saw that fructose did not cause feelings of fullness, whereas the participants reported an increase in feelings of fullness after the glucose drink,” said Page, who is also chair of the Maternal-Child Health section of the USC Diabetes and Obesity Research Institute.

The research was published in the Journal of the American Medical Association, and was conducted while Page was on faculty at Yale. Research funding was provided by the Doris Duke Charitable Foundation.

The American Association for the Advancement of Science has posted a podcast of Page discussing the research.

The study used functional magnetic resonance imaging to map changes in the brains of 20 test subjects who consumed sugary drinks. The researchers found that the glucose drink suppressed activity in the hypothalamus and other brain regions that regulate appetite, motivation and reward processing, while the fructose drink did not. The different responses to fructose were associated with reduced levels of the hormone insulin, which sends signals to the brain that a person has had enough to eat.

Fructose, found with glucose in many fruits and vegetables, as well as table sugar, is an ingredient in high-fructose corn syrup, a popular sweetener. High-fructose corn syrup is found in certain soft drinks and processed foods, and consumption of the sweetener has been on the rise over the past few decades. Rates of obesity have increased in parallel, the researchers noted.

In continuing research, Page’s team is studying whether obese people have exaggerated brain reward and hunger responses to fructose and whether different ethnic groups respond differently to fructose and glucose.

The original article was published on the Keck School of Medicine website

[goodwithagun]

Same here. We don’t shy away from fat, and none of our ingredients have ingredients. It’s pretty amazing how we don’t have to “watch what we eat” anymore. We’ve eliminated processed foods (homemade pizza with fresh mozzarella is so much better than delivery!) and low-fat, fat-free, sugar-free, low-cal “food.”

[BenLurkin]

If you’re ever in Brooklyn:
http://www.youtube.com/watch?v=eXJz0zbeksE

[Mastador1]

Maybe she just saw Weiner.

[Cyman]

The high fructose corn syrup chupacabra is the bastard son of man made global warming.

[Overtaxed]

White is not her color.

[cicero2k]

What I’ve cut completely out of my diet in the past 10 years:

1. Beer
2. Wheat snacks of any kind
3. Pancakes and waffles
4. Ice cream, milk
5. Breakfast baked items (rolls, pound cake)
6. Soda (sweet and artificially sweet)

85% of these are out of my diet:

1. Cheese
2. Pizza, pasta
3. Bread and bagels
4. Cookies, cake

Even so, I’m barely at normal weight. Each year something new has to be banned.

[dfwgator]

Why cut out cheese, they have little or no carbs.

[flaglady47]

“What I’ve cut completely out of my diet in the past 10 years:

1. Beer
2. Wheat snacks of any kind
3. Pancakes and waffles
4. Ice cream, milk
5. Breakfast baked items (rolls, pound cake)
6. Soda (sweet and artificially sweet)

85% of these are out of my diet:

1. Cheese
2. Pizza, pasta
3. Bread and bagels
4. Cookies, cake”

And then you commit suicide because life’s not worth living anymore.

[bgill]

Eating celery has never made anyone fat.

[BfloGuy]

Weight Gain May Be Influenced By Fructose Consumption

Well, duh.

Any food that increases your blood-sugar level like fructose does (wheat actually increases it more) will pile on the pounds. If you want to lose weight, don't eat it.

[Buffalo Head]

"Eating celery has never made anyone fat."

Are you certain of that? Cows eating nothing but grass can get very fat and full of cloresteral.

[neverdem]

FReepmail me if you want on or off the diabetes ping list.

Check the links in comment# 1: 'When you eat 120 calories of glucose, less than one calorie is stored as fat. 120 calories of fructose results in 40 calories being stored as fat."

[jdege]

Fructose and glucose are processed very differently.

[SkyDancer]

http://kimberlysnyder.net/blog/2012/04/14/the-difference-in-how-fructose-and-glucose-affect-your-body/

[verga]

My brother in Law sent me an article about HFCS and it was reflected in this article. I didn't want to believe it at first until I started reading labels more closely. It seems that the more a food is processed the closer to the top of the list is the HFCS. My wife and I began to eliminate it from our diets as much as possible and in the last 6 months I have been working on eliminating flour as well. So much of what you see on grocery store shelves contains one or both of these in copious amounts.

[Eric in the Ozarks]

Drive west out of Minneapolis into sugar beet territory and you'll drive by some of the richest farms and wealthiest farmers in the world.

[jdege]

A better reference:

Intermediary metabolism of fructose