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Researchers Find Tinnitus Cause and Treatment
Yahoo ^ | Wed, May 29, 2013 | By Vonda J. Sines

Posted on 06/14/2013 10:28:24 AM PDT by Red Badger

Pennsylvania scientists have discovered the cause of the chronic disorder known as tinnitus, and have also found a way to treat it. Their goal is a preventive strategy for individuals whose work situations could cause them to be exposed to very loud noise.

University of Pittsburgh School of Medicine researchers found that an epilepsy drug known as retigabine prevents tinnitus in animal models, according to ScienceDaily. They published their findings in the Proceedings of the National Academy of Sciences.

Strictly speaking, tinnitus isn't a condition, but a symptom of some type of disorder, like hearing loss related to age, a circulatory system ailment, or an injury to the ear, the Mayo Clinic reports. Tinnitus sufferers describe the buzzing, ringing, roaring, hissing, clicking, and other sounds it creates in their ears as annoying to varying degrees. For some, it's debilitating. Since there's no cure for tinnitus itself, doctors attempt to identify and treat the underlying cause.

According to the National Institute on Deafness and Other Communications Disorders, about 25 million Americans have suffered from tinnitus. Among those who are at least 65, the disorder affects about 14 percent of women and more than 12 percent of men.

Knowing that tinnitus is incurable and that hearing aids don't help some patients, the Pittsburgh team sought to first find the underlying cause, then a way to treat it. They knew from prior work with mice that a connection exists between tinnitus and overactive dorsal cochlear nucleus (DCN) cells in the brain through which potassium ions travel. They found that hyperactivity of DCN cells is the result of a reduced level of activity in structures known as KCNQ channels.

The researchers conducted experiments that exposed mice to regulated amounts of noise, then identified those that had developed tinnitus.

(Excerpt) Read more at news.yahoo.com ...


TOPICS: Health/Medicine
KEYWORDS: brain; ear; hearing; tinnitus
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To: moose07

Thank you, sweet man.


61 posted on 06/14/2013 2:27:17 PM PDT by TheOldLady
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To: ckilmer

Done!.............


62 posted on 06/14/2013 2:27:22 PM PDT by Red Badger (Want to be surprised? Google your own name......Want to have fun? Google your friend's names........)
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To: Red Badger

Please add me.

And ping to Post #49 for another new list member for you.


63 posted on 06/14/2013 2:31:58 PM PDT by TheOldLady
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To: TheOldLady

Done!....and Done!........


64 posted on 06/14/2013 2:34:44 PM PDT by Red Badger (Want to be surprised? Google your own name......Want to have fun? Google your friend's names........)
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To: Red Badger

Add me to the buzz list please...


65 posted on 06/14/2013 2:36:47 PM PDT by Gene Eric (Don't be a statist!)
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To: Gene Eric

Done!............


66 posted on 06/14/2013 2:40:52 PM PDT by Red Badger (Want to be surprised? Google your own name......Want to have fun? Google your friend's names........)
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To: Red Badger

“...researchers conducted experiments that exposed mice to regulated amounts of noise, then identified those that had developed tinnitus...”
-
How did they know which ones of the mouses developed tinnitus?


67 posted on 06/14/2013 2:50:08 PM PDT by Repeal The 17th (We have met the enemy and he is us.)
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To: Red Badger
Done!.............

Please add me also Red. Thanks!

68 posted on 06/14/2013 2:54:31 PM PDT by houeto (https://secure.freerepublic.com/donate/)
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To: Red Badger; All

Retigabine is real, my friend!


69 posted on 06/14/2013 4:56:56 PM PDT by pluvmantelo (Clinton-traitor Bush-feckless Obama-traitor & feckless. The boomer presidents have been a disaster)
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To: Red Badger

Thank you for the ping....


70 posted on 06/14/2013 8:21:06 PM PDT by TinCan
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To: moose07

Thanks for the ping!


71 posted on 06/14/2013 8:49:47 PM PDT by Alamo-Girl
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To: Red Badger

Right there with ya brotha! I feel like I am n the Swamplands of Louisiana most nights and AM’s!! Then again.. early AM’s there are Russian patriotic chants from the early 20’s! What a crazy condition!


72 posted on 06/14/2013 8:57:14 PM PDT by acapesket
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To: GBA

I know what you mean about entertaining. For me it’s 10% entertaining 90% nuisance. Mine varies, too. At worst it’s dozen miniature stainless steel violins inside my ear. Like right now.


73 posted on 06/14/2013 9:11:40 PM PDT by far sider
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To: GBA
Mine was actually caused by a girl in the doctors office....she was sent in to clean my ears...usually a piston syringe is used and is actually banked off the side of the ear and hits the drum with a some what forceful squirt of water. She couldn't loosen what she wanted to that way so she used the piston syringe straight back onto my ear drum, causing me to scream....thats when my tinnitus started. I ended up going to an otolaryngolist. He gave me all kinds of tests including loss of hearing...nope he could not find why I had the ringing.....That was about 45 years ago and I still have it today...it seems it gets louder when the weather is unstable. Along with that I get nausea when its loud....Dramamine helps with the nausea. I use to be on anti-vert, but that was expensive.

As I have aged, I do find (like you mentioned) it stops and I don't know why, its just "hey this silence is great" I have learned to live with it but silence is golden.....:O) I think that somehow the ear drum was damaged in the doctors office....

A few years back I went to a new doctor for ear cleaning. I told her of my experience and one ear was easily cleaned, but she also couldn't get the one ear cleaned...She took about 20 minutes to get the wax off, but said the ear drum was quite red when the wax came off....Now I'm in my 7th decade and my loss of hearing is catching with with my tinnitus of years ago. My hearing was perfect with it when I went to the specialist, kinda of losing hearing that is normal for my age......

74 posted on 06/14/2013 9:29:01 PM PDT by goat granny
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To: Red Badger

LOL love that kitty....thanks for the ping


75 posted on 06/14/2013 9:29:56 PM PDT by goat granny
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To: Resolute Conservative

and after they answer that damn phone, see whos ringing the door bell damn it..


76 posted on 06/14/2013 9:31:49 PM PDT by goat granny
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To: Red Badger

Thank you so much for the ping. Mine is really loud today and is making it hard to think. I need to check on this.


77 posted on 06/15/2013 4:34:26 AM PDT by Vor Lady
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To: cuban leaf

“nerves leaks out through the sheath”

wouldn’t this be also called ‘crosstalk’


78 posted on 06/15/2013 7:36:22 AM PDT by George from New England (escaped CT in 2006, now living north of Tampa)
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To: far sider
Like right now.

What was that? I can't hear you over all the racket in my head.

79 posted on 06/15/2013 8:02:10 AM PDT by GBA (Here in the Matrix, life is but a dream.)
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To: Red Badger
Interesting.

5.56mm

80 posted on 06/15/2013 8:06:48 AM PDT by M Kehoe
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