Viagra against heart failure: Researchers at the RUB and from Rochester throw light on the mechanism

Ruhr-University Bochum ^ | December 23, 2011

[decimon]

Circulation: active ingredient sildenafil makes stiffened cardiac walls elastic again

How sildenafil, the active ingredient in Viagra, can alleviate heart problems is reported by Bochum's researchers in cooperation with colleagues from the Mayo Clinic in Rochester (Minnesota) in the journal Circulation. They studied dogs with diastolic heart failure, a condition in which the heart chamber does not sufficiently fill with blood. The scientists showed that sildenafil makes stiffened cardiac walls more elastic again. The drug activates an enzyme that causes the giant protein titin in the myocardial cells to relax. "We have developed a therapy in an animal model that, for the first time, also raises hopes for the successful treatment of patients" says Prof. Dr. Wolfgang Linke of the RUB Institute of Physiology.

[Silentgypsy]

I’m so sorry. Prayers up for you.
Do you think you might give it a shot and, if it makes you feel worse, just discontinue it?

[count-your-change]

Vigor Morris.