Posted on 07/05/2010 4:58:21 PM PDT by decimon
Long-term supplementation with dietary antioxidants has beneficial effects on sugar and fat metabolism, blood pressure and arterial flexibility in patients with multiple cardiovascular risk factors. Researchers writing in BioMed Central's open access journal Nutrition and Metabolism report these positive results in a randomized controlled trial of combined vitamin C, vitamin E, coenzyme Q10 and selenium capsules.
Reuven Zimlichman worked with a team of researchers from Wolfson Medical Center, Israel, to carry out the study in 70 patients from the centre's hypertension clinic. He said, "Antioxidant supplementation significantly increased large and small artery elasticity in patients with multiple cardiovascular risk factors. This beneficial vascular effect was associated with an improvement in glucose and lipid metabolism as well as significant decrease in blood pressure".
Previous results from clinical trials into the cardiovascular health effects of antioxidants have been equivocal. In order to shed more light onto the matter, Zimlichman and his colleagues randomised the 70 patients to receive either antioxidants or placebo capsules for six months. Tests at the beginning of the trial, after three months and at the six month mark revealed that the patients in the antioxidant group had more elastic arteries (a measure of increased cardiovascular health) and better blood sugar and cholesterol profiles. According to Zimlichman, "The findings of the present study justify investigating the overall clinical impact of antioxidant treatment in patients with multiple cardiovascular risk factors".
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Notes to Editors
1. Effect of long-term treatment with antioxidants (vitamin C, vitamin E, coenzyme Q10 and selenium) on arterial compliance, humoral factors and inflammatory markers in patients with multiple cardiovascular risk factors. Marina Shargorodsky, Ortal Debbi, Zipora Matas and Reuven Zimlichman Nutrition & Metabolism (in press)
During embargo, article available here: http://www.nutritionandmetabolism.com/imedia/1415754288304238_article.pdf?random=452924
After the embargo, article available at the journal website: http://www.nutritionandmetabolism.com/
Please name the journal in any story you write. If you are writing for the web, please link to the article. All articles are available free of charge, according to BioMed Central's open access policy.
Article citation and URL available on request at press@biomedcentral.com on the day of publication.
2. Nutrition & Metabolism is an open access, peer-reviewed, online journal focused on the integration of nutrition, exercise physiology, clinical investigations, and molecular and cellular biochemistry of metabolism.
3. BioMed Central (http://www.biomedcentral.com/) is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector.
Ping
That’s interesting. Are they recommending a single suppliment or several and at what dosage?
Small sample size n=70. Worth expanding the study.
This has been proven so many times I can’t believe it’s news anymore. Antioxidant vitamins are beneficial for many conditions.
When I initially tried taking Coenzyme Q10 for hypertension, I accidentally discovered sleep. Decades of insomnia went away in about 8 days. When I stop taking Q10, I stop sleeping. Apparently I am deficient. When I started taking the stuff I went online to read about side effects. There are many very very positive ‘side effects’ of Q10 and I have yet to find any negatives. I read that it can reverse heart failure and gum disease. When I had braces on my teeth, the Q10 seemed to improve my gum health. However, it is an expensive supplement compared with E or C or Calcium etc. And, for my own experience, only a few brands have any effect on me. I hate trying new brands because they are expensive and after about 5 days I stop sleeping and feel achy. It makes a health difference for me and I wanted to mention it in case anyone was interested in trying it.
Are they planning on adding fish oil to the trials, or increasing N?
CoQ10 doesn’t do anything for my sleep quality but it does alleviate the minor muscles pains that result from statin usage. If the 100 mg/day helps with cardiovascular health also, that’s great.
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