Allopurinol Lowers Fructose-Triggered Hypertension

Medpage Today ^ | September 23, 2009 | Kristina Fiore

[MetaThought]

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A diet high in fructose can increase uric acid levels, but allopurinol may help lower the resulting high blood pressure, researchers say.

Men who took the drug to mitigate the effects of a high-fructose diet did not experience the increase in blood pressure observed among men on the same diet who did not take the drug, Richard Johnson, MD, of the University of Colorado, and colleagues said at the American Heart Association's High Blood Pressure Research Conference in Chicago.

"These results support the idea that fructose, such as present in table sugar and high-fructose corn syrup, could have a role in the epidemic of obesity and metabolic syndrome," Johnson said. "Further, they suggest that [the two sweeteners] could have a role in high blood pressure, and that this might be mediated by uric acid."

Eating a lot of fructose -- typically from sugary drinks sweetened with high-fructose corn syrup -- has previously been associated with increased levels of uric acid.

"It has been known for a long time that fructose can raise uric acid levels, and in the last few years epidemiological studies have also confirmed that those with the highest fructose intake have higher uric acid levels," Johnson said.

[RedWhiteBlue]

Thanks for the link, I watched it last night. I will watch it again when I get the opportunity, just to let it sink in a little more. There are some questions I would ask that Dr if I could.

[SunkenCiv]

These results support the idea that fructose, such as present in table sugar and high-fructose corn syrup, could have a role in the epidemic of obesity and metabolic syndrome

Thanks MetaThought. The obesity epidemic has come about because of Al Gore's invention, the Internet. :')