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Broccoli component limits breast cancer stem cells, U-M study finds
University of Michigan Health System ^ | May 3, 2010 | Unknown

Posted on 05/03/2010 10:57:45 AM PDT by decimon

A compound derived from broccoli could help prevent or treat breast cancer by targeting cancer stem cells -- the small number of cells that fuel a tumor’s growth -- according to a new study from researchers at the University of Michigan Comprehensive Cancer Center. The study tested sulforaphane, a component of broccoli and broccoli sprouts, in both mice and cell cultures. Researchers found sulforaphane targeted and killed the cancer stem cells and prevented new tumors from growing.

“Sulforaphane has been studied previously for its effects on cancer, but this study shows that its benefit is in inhibiting the breast cancer stem cells. This new insight suggests the potential of sulforaphane or broccoli extract to prevent or treat cancer by targeting the critical cancer stem cells,” says study author Duxin Sun, Ph.D., associate professor of pharmaceutical sciences at the U-M College of Pharmacy and a researcher with the U-M Comprehensive Cancer Center.

>

The concentrations of sulforaphane used in the study were higher than what can be achieved by eating broccoli or broccoli sprouts. Prior research suggests the concentrations needed to impact cancer can be absorbed by the body from the broccoli extract, but side effects are not known. While the extract is available in capsule form as a supplement, concentrations are unregulated and will vary.

>

(Excerpt) Read more at 2.med.umich.edu ...


TOPICS: Health/Medicine
KEYWORDS: breastcancer; broccoli; cancer; sulforaphane

1 posted on 05/03/2010 10:57:45 AM PDT by decimon
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To: neverdem; DvdMom; grey_whiskers

Ping.


2 posted on 05/03/2010 10:58:22 AM PDT by decimon
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To: decimon

I love broccoli...always have.And now that I’m older I find that I have “man boobs” so I’ll start to eat even more!


3 posted on 05/03/2010 11:00:18 AM PDT by Gay State Conservative (Host The Beer Summit-->Win The Nobel Peace Prize!)
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To: Gay State Conservative

I eat about 1-2 cups per day.


4 posted on 05/03/2010 11:06:31 AM PDT by LukeL (Yasser Arafat: "I'd kill for a Nobel Peace Prize")
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To: Gay State Conservative

The Power Puff girls have a funny episode about eating brocolli. Don’t ask me how I know..... I like Mojo Jojo too!


5 posted on 05/03/2010 11:11:51 AM PDT by refermech
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To: Gay State Conservative

The Power Puff girls have a funny episode about eating brocolli. Don’t ask me how I know..... I like Mojo Jojo too!


6 posted on 05/03/2010 11:12:06 AM PDT by refermech
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To: decimon

There’s a lady I know
If I didn’t know her
She’d be the lady I didn’t know.

And my lady, she went downtown
She bought some broccoli
She brought it home.

She’s chopping broccoli
Chopping broccoli
Chopping broccoli
Chopping broccoli

She’s chopping broccoli
She’s chopping broccoli
She’s chop.. ooh!
She’s chopping broccola-ah-ie!


7 posted on 05/03/2010 11:14:11 AM PDT by dfwgator
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To: refermech
My favorite is Chopping Broccoli from Carvey, LOL!!
8 posted on 05/03/2010 11:21:07 AM PDT by MozarkDawg
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To: dfwgator

Ah, ya beat me, posting as I typed!


9 posted on 05/03/2010 11:21:42 AM PDT by MozarkDawg
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To: decimon

10 posted on 05/03/2010 11:26:03 AM PDT by Daffynition ( Someday we'll know why love can't move a mountain.)
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To: decimon; Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ovrtaxt; ...
stem cell ping

Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells

Sulforaphane has been mentioned on at least six threads now using it as a keyword.

11 posted on 05/03/2010 11:26:23 AM PDT by neverdem (Xin loi minh oi)
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To: MozarkDawg

Har! That was funny!!


12 posted on 05/03/2010 11:39:30 AM PDT by refermech
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To: decimon

even cancer won’t eat broccolli!


13 posted on 05/03/2010 11:56:03 AM PDT by HospiceNurse
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To: neverdem
Sulforaphane has been mentioned on at least six threads now using it as a keyword.

It's like electrical banana; a sudden craze.

14 posted on 05/03/2010 12:09:17 PM PDT by decimon
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To: Daffynition

Looks lie the salad bar at Cannibals.


15 posted on 05/03/2010 12:11:15 PM PDT by decimon
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To: decimon
We have been using Sulforaphane Glucosinolate or SGS (made from Broccoli Seed Extract)for about 6 years at the natural medicine office I manage.

FYI - The best brand with the most studies with the correct dosage is from Xymogen.

16 posted on 05/03/2010 12:36:00 PM PDT by BossLady (<----Butler Alumnus - proud of my Dawgs!!!)
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To: BossLady

Is that as a treatment or as a preventative?


17 posted on 05/03/2010 12:38:40 PM PDT by reformedliberal ("If it takes a blood bath, let's get it over with." R. Reagan)
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To: reformedliberal
Here is some info -

http://www.xymogen.com/uploads/attributes/DRS132-oncoplex1007.pdf

We use it as a chemoprotective and recommend using it after treatment....and also if there is a family history, we recommend using it as well.

18 posted on 05/03/2010 12:47:19 PM PDT by BossLady (<----Butler Alumnus - proud of my Dawgs!!!)
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To: decimon
You know what's good for you B-A-B-Y-Y-Y-Y-Y-Y-Y-y-y-y-y-y-y-y-y-y-y-y-y-!!!


19 posted on 05/03/2010 4:17:26 PM PDT by Daffynition ( Someday we'll know why love can't move a mountain.)
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