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Protein cue that allows limb re-growth
The Times of India ^ | 3rd Nov., 2007 | AFP

Posted on 11/03/2007 4:39:05 AM PDT by CarrotAndStick

WASHINGTON: Researchers in Britain discovered a protein's molecular signal that apparently plays a key role in allowing newts, which are amphibians to re-grow severed limbs, a report in the journal Science says.

The finding could provide insights in the field of regenerative medicine relating to mammals and humans, said Anoop Kumar of the University College London (UCL), the report's main author.

Biologists have long been intrigued at how newts and other amphibians can re-grow severed limbs, never fully understanding the biological process.

The protein called nAG, produced by nerve and skin cells, apparently plays a key role in stimulating blastema cells, the undifferentiated cells from which a new organ or limb can grow, Kumar and colleagues at University College London and AA Garza-Garcia at the National Institute for Medical Research in London found.

Both neurons and epidermal cells near the wound secrete the protein.

Researchers discovered however that even when the nerve was severed beneath the stump tip, they could prompt formation of a blastema by inducing cells artificially to express the protein.

Understanding such molecular signals could be key to scientists some day carrying out cellular regeneration of missing parts of the human body.


TOPICS: Health/Medicine; Science
KEYWORDS: amputation; limb; medicine; regeneration

1 posted on 11/03/2007 4:39:06 AM PDT by CarrotAndStick
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To: CarrotAndStick

Look for the first use of this product in those special “male enhancement” products you see on TV and in 80% of your spam e-mails.


2 posted on 11/03/2007 4:45:23 AM PDT by Hardastarboard (DemocraticUnderground.com is an internet hate site.)
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To: CarrotAndStick
"Protein cue that allows limb re-growth"

Gee, I didn't see the words "embryonic stem cells" anywhere. That just can't be right--I thought that it was going to be absolutely necessary to kill babies in order to re-grow body parts.

3 posted on 11/03/2007 4:48:33 AM PDT by Wonder Warthog (The Hog of Steel-NRA)
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To: CarrotAndStick
Scissors, anyone?

4 posted on 11/03/2007 5:29:44 AM PDT by Dahoser (America's great untapped alternative energy source: The Founding Fathers spinning in their graves.)
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To: CarrotAndStick

5 posted on 11/03/2007 6:13:59 AM PDT by martin_fierro (< |:)~)
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To: martin_fierro

I’m sure O.J. doesn’t want this technology developed, no reason...


6 posted on 11/03/2007 8:24:04 AM PDT by SunkenCiv (Profile updated Monday, October 22, 2007. https://secure.freerepublic.com/donate/)
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