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Reuters: Premature ejaculation drug delays climax
Reuters ^ | 5.23.05

Posted on 05/23/2005 10:22:55 AM PDT by ambrose

Premature ejaculation drug delays climax

Monday May 23, 1:13 pm ET

WASHINGTON (Reuters) - The first drug formulated to treat premature ejaculation delayed climax and increased reported satisfaction in a late-stage study, its developer, Johnson & Johnson (NYSE:JNJ - News), said on Monday.

A Phase III clinical trial of 2,614 men showed the drug provided "significant improvements in sexual function, including ejaculatory control, satisfaction with sexual intercourse for men and their partners, and increases in intravaginal ejaculatory latency time," Ortho-McNeil Pharmaceutical, a unit of J&J, said in a statement.

The drug, called dapoxetine, is being co-developed by J&J's Alza Corp. and Johnson & Johnson Pharmaceutical Services, LLC units. The company's Ortho-McNeil Pharmaceutical unit will market the drug in the United States if it receives U.S. Food and Drug Administration approval.

The American Urological Association estimates that premature ejaculation affects anywhere between 27 percent and 34 percent of men across all age ranges. Erectile dysfunction, the condition that made Pfizer's (NYSE:PFE - News) impotence drug Viagra into a blockbuster, affects an estimated 10 percent to 12 percent of men.

"The impact premature ejaculation can have on men and their partners can be devastating for a relationship, and, currently, there are no truly optimal therapies for PE," said Dr. Jon Pryor, chairman and program director of the Department of Urologic Surgery at the University of Minnesota, who led the study.

Researchers working on the drug reported last month that they could define premature ejaculation. They said a man with the condition took 1.8 minutes to ejaculate after beginning intercourse compared to 7.3 minutes for most men.

They call this Intravaginal Ejaculatory Latency Time and is timed by giving the man or his sexual partner a stopwatch.

In a study presented to a meeting of the American Urological Association in San Antonio, Texas, researchers said men who took dapoxetine at doses of either 30 mg or 60 mg had a three- to four-fold increase in this time compared to men given a placebo.

The percentage of men rating control over ejaculation as "fair to very good" increased from 2.5 percent before getting the drug, to 51.8 percent afterwards for men who got the lower dose, to 58 percent of men given the higher dose.

Of the men who got the placebo, 3.5 percent reported fair to very good control before getting the dummy pill and 26.4 percent said so afterwards.

"The percentage of men rating sexual satisfaction as 'good to very good' almost doubled with dapoxetine 30 mg (20.2 percent to 38.7 percent) and 60 mg (22.3 percent to 46.5 percent)," the company said. Just under 25 percent of men who got the placebo reported good sexual satisfaction.


TOPICS: Health/Medicine
KEYWORDS: alza; dapoxetine; ejaculatorycontrol; jnj; johnsonjohnson; latecomers; menshealth; minutemen; nosatisfaction; orthomcneil; patienceisavirtue; pe; prematureejaculation; urologic; urology
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To: KarlInOhio

I think it's been helping ugly people have sex for a lot longer than that though.


21 posted on 05/23/2005 10:32:27 AM PDT by biblewonk (Socialism isn't all bad.)
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To: ambrose
---intravaginal ejaculatory latency time---

this is pretty much the definition of "too much information."

22 posted on 05/23/2005 10:32:30 AM PDT by smonk
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To: ambrose

Interesting to see that at least someone at Reuters is actually reading his Email spam...


23 posted on 05/23/2005 10:34:12 AM PDT by cartan
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To: NRA2BFree

When and where can I get th.... errr..., I mean---HAHAHA!! What kinda wimp has problems like this?


24 posted on 05/23/2005 10:34:32 AM PDT by Right Angler
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To: Pukin Dog
So? Stiletto heels poking you in the kidneys works just as well.

I'm afraid I'll need a Kama Sutra reference number for that, uh...posture.

25 posted on 05/23/2005 10:34:38 AM PDT by AngryJawa (Will Work For Ammo)
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To: ambrose
Intravaginal Ejaculatory Latency Time

That would be a great name for a band.

26 posted on 05/23/2005 10:35:19 AM PDT by Choose Ye This Day (Somos un país soberano en una época de guerra. ¿Por qué no podemos defender nuestra frontera?)
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To: ambrose
compared to 7.3 minutes for most men

Huh! They must have TiVo.

27 posted on 05/23/2005 10:36:28 AM PDT by Choose Ye This Day (Somos un país soberano en una época de guerra. ¿Por qué no podemos defender nuestra frontera?)
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To: smonk

Well, it tells us that no homosexuals were involved in this study.


28 posted on 05/23/2005 10:38:25 AM PDT by newzjunkey (Remind Liberal Cowards Why America Freed Iraq: http://massgraves.info/)
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To: skimbell
"delaying drug" and couple it with one of those drugs that cause "occasional erections lasting longer than 4 hours

I am buying stock in defibrilators for home use.

29 posted on 05/23/2005 10:39:51 AM PDT by frithguild (Defining hypocrisy - Liberals fear liberty.)
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To: pissant
13 posted on 05/23/2005 1:30:01 PM EDT by pissant (I've got a headache)
 
13?  You're slippin', fella.
 
Owl_Eagle

(If what I just wrote makes you sad or angry,

 it was probably sarcasm)

30 posted on 05/23/2005 10:42:12 AM PDT by End Times Sentinel (In Memory of my Dear Friend Henry Lee II)
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To: ambrose
increases in intravaginal ejaculatory latency time

Scientists sure have a way of putting things... Wonder how Eminem would put it... (I wouldn't DARE)...

31 posted on 05/23/2005 10:44:36 AM PDT by Conservatrix ("He who stands for nothing will fall for anything.")
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To: Choose Ye This Day

Relax don't do it
When you want to go to it
Relax don't do it
When you want to come
Relax don't do it
When you want to come
When you want to come


32 posted on 05/23/2005 10:49:52 AM PDT by Choose Ye This Day (Somos un país soberano en una época de guerra. ¿Por qué no podemos defender nuestra frontera?)
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To: AngryJawa
That is so sad.
33 posted on 05/23/2005 10:52:43 AM PDT by Pukin Dog (Sans Reproache)
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To: newzjunkey
---Well, it tells us that no homosexuals were involved in this study.---

what would be "premature" in that scenario?

34 posted on 05/23/2005 10:53:47 AM PDT by smonk
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To: smonk

No, I think the question he's getting at is:

What would be "vaginal" in that scenario?


35 posted on 05/23/2005 10:58:37 AM PDT by Choose Ye This Day (Somos un país soberano en una época de guerra. ¿Por qué no podemos defender nuestra frontera?)
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To: Choose Ye This Day
---No, I think the question he's getting at is:----

---What would be "vaginal" in that scenario?---

no vagina, no vaginal orgasm, nothing to be premature about, is there?

maybe I just don't understand homosexual sex very well.

36 posted on 05/23/2005 11:10:22 AM PDT by smonk
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To: Pukin Dog
That is so sad.

Yes. Indeed it is.

With any luck, I'll get to be a naval aviator in my next life. Chicks dig the wings...8^)

37 posted on 05/23/2005 11:11:09 AM PDT by AngryJawa (Will Work For Ammo)
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To: AngryJawa
Is it the wings?

Damn.

I always thought it was the fact that I would be gone 6-8 months of the year, while my credit cards would always be around. Silly me.

38 posted on 05/23/2005 11:45:45 AM PDT by Pukin Dog (Sans Reproache)
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To: ambrose

What happens when a guy takes Viagra and this stuff at the same time?


39 posted on 05/23/2005 11:48:57 AM PDT by Protagoras (The goal is power, the tool is deceit.)
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To: ambrose

Well, if it's a "premature ejaculation" drug, shouldn't it be causing faster climaxes? I mean, I got things to do here, I'm a busy guy!


40 posted on 05/23/2005 11:51:34 AM PDT by Larry Lucido
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