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Reuters: Premature ejaculation drug delays climax
Reuters ^ | 5.23.05

Posted on 05/23/2005 10:22:55 AM PDT by ambrose

Premature ejaculation drug delays climax

Monday May 23, 1:13 pm ET

WASHINGTON (Reuters) - The first drug formulated to treat premature ejaculation delayed climax and increased reported satisfaction in a late-stage study, its developer, Johnson & Johnson (NYSE:JNJ - News), said on Monday.

A Phase III clinical trial of 2,614 men showed the drug provided "significant improvements in sexual function, including ejaculatory control, satisfaction with sexual intercourse for men and their partners, and increases in intravaginal ejaculatory latency time," Ortho-McNeil Pharmaceutical, a unit of J&J, said in a statement.

The drug, called dapoxetine, is being co-developed by J&J's Alza Corp. and Johnson & Johnson Pharmaceutical Services, LLC units. The company's Ortho-McNeil Pharmaceutical unit will market the drug in the United States if it receives U.S. Food and Drug Administration approval.

The American Urological Association estimates that premature ejaculation affects anywhere between 27 percent and 34 percent of men across all age ranges. Erectile dysfunction, the condition that made Pfizer's (NYSE:PFE - News) impotence drug Viagra into a blockbuster, affects an estimated 10 percent to 12 percent of men.

"The impact premature ejaculation can have on men and their partners can be devastating for a relationship, and, currently, there are no truly optimal therapies for PE," said Dr. Jon Pryor, chairman and program director of the Department of Urologic Surgery at the University of Minnesota, who led the study.

Researchers working on the drug reported last month that they could define premature ejaculation. They said a man with the condition took 1.8 minutes to ejaculate after beginning intercourse compared to 7.3 minutes for most men.

They call this Intravaginal Ejaculatory Latency Time and is timed by giving the man or his sexual partner a stopwatch.

In a study presented to a meeting of the American Urological Association in San Antonio, Texas, researchers said men who took dapoxetine at doses of either 30 mg or 60 mg had a three- to four-fold increase in this time compared to men given a placebo.

The percentage of men rating control over ejaculation as "fair to very good" increased from 2.5 percent before getting the drug, to 51.8 percent afterwards for men who got the lower dose, to 58 percent of men given the higher dose.

Of the men who got the placebo, 3.5 percent reported fair to very good control before getting the dummy pill and 26.4 percent said so afterwards.

"The percentage of men rating sexual satisfaction as 'good to very good' almost doubled with dapoxetine 30 mg (20.2 percent to 38.7 percent) and 60 mg (22.3 percent to 46.5 percent)," the company said. Just under 25 percent of men who got the placebo reported good sexual satisfaction.


TOPICS: Health/Medicine
KEYWORDS: alza; dapoxetine; ejaculatorycontrol; jnj; johnsonjohnson; latecomers; menshealth; minutemen; nosatisfaction; orthomcneil; patienceisavirtue; pe; prematureejaculation; urologic; urology
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1 posted on 05/23/2005 10:22:56 AM PDT by ambrose
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To: ambrose

I expected some hilarious comments would be posted here, but was disappointed to see there were none.


2 posted on 05/23/2005 10:24:03 AM PDT by Muzzle_em
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To: ambrose

Surely this, too, will be covered by Medicare & Medicaid.

My tax dollars at work.


3 posted on 05/23/2005 10:27:02 AM PDT by newgeezer (fundamentalist, regarding the Constitution AND the Holy Bible, i.e. words mean things!)
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To: Muzzle_em

The hilarious comments have been delayed three to fourfold...


4 posted on 05/23/2005 10:27:04 AM PDT by stuartcr (Everything happens as God wants it to.....otherwise, things would be different.)
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To: ambrose; TheBigB; pissant
Reuters: Premature ejaculation drug delays climax

Yeah.

But you have to wait 5 years before it's on the market.

< |:)~

5 posted on 05/23/2005 10:27:30 AM PDT by martin_fierro (_____oooo_( ° ¿ ° )_oooo_____)
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To: Muzzle_em; ambrose

Has no one come up with a brand name yet ?

Keepitin ? Climaxin ?


6 posted on 05/23/2005 10:27:32 AM PDT by Sam the Sham
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To: ambrose

"They call this Intravaginal Ejaculatory Latency Time and is timed by giving the man or his sexual partner a stopwatch."

Here he comes, here comes Speed Racer.


7 posted on 05/23/2005 10:28:09 AM PDT by KeyesPlease
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To: Muzzle_em
I expected some hilarious comments would be posted here, but was disappointed to see there were none.

Maybe you looked prematurely. The posters may just be holding back....

8 posted on 05/23/2005 10:28:16 AM PDT by Mannaggia l'America
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To: ambrose

This will have a huge black market among teenage boys.


9 posted on 05/23/2005 10:28:39 AM PDT by newzjunkey (Remind Liberal Cowards Why America Freed Iraq: http://massgraves.info/)
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To: Muzzle_em
It takes me at least five minutes to post hilarious comments.
10 posted on 05/23/2005 10:28:49 AM PDT by KarlInOhio (Relying on government for your retirement is like playing Russian roulette with an semi auto pistol.)
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To: ambrose; newgeezer

How about a "pick up chicks" drug.


11 posted on 05/23/2005 10:29:16 AM PDT by biblewonk (Socialism isn't all bad.)
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To: Muzzle_em

This will devastate the baseball statistics industry! The drugging of America must stop! 8^)


12 posted on 05/23/2005 10:29:54 AM PDT by AngryJawa (Will Work For Ammo)
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To: martin_fierro

how timely of you....

http://www.freerepublic.com/focus/f-chat/1408772/posts


13 posted on 05/23/2005 10:30:01 AM PDT by pissant (I've got a headache)
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To: Muzzle_em
Jezuz, can you imagine what you get if you take this "delaying drug" and couple it with one of those drugs that cause "occasional erections lasting longer than 4 hours, while uncommon, do require immediate medical attention?

Hell, you'd have to register yourself as a lethal weapon!

14 posted on 05/23/2005 10:30:04 AM PDT by skimbell
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To: ambrose

A premature ejaculation drug has been around for years. It's called whisky.


15 posted on 05/23/2005 10:30:12 AM PDT by Drew68 (IYAOYAS! Semper Gumby!)
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To: ambrose

I wonder how long this thread is going to last? LOL


16 posted on 05/23/2005 10:30:27 AM PDT by NRA2BFree (Under Construction.)
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To: biblewonk
How about a "pick up chicks" drug.

Already being produced.


17 posted on 05/23/2005 10:30:57 AM PDT by KarlInOhio (Relying on government for your retirement is like playing Russian roulette with an semi auto pistol.)
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To: Drew68
A premature ejaculation drug has been around for years. It's called whisky.

Yup. It's effective, but it really stings. 8^)

18 posted on 05/23/2005 10:31:30 AM PDT by AngryJawa (Will Work For Ammo)
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To: KarlInOhio

It's also a "chick beautification" drug.


19 posted on 05/23/2005 10:31:39 AM PDT by biblewonk (Socialism isn't all bad.)
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To: ambrose
So? Stiletto heels poking you in the kidneys works just as well.
20 posted on 05/23/2005 10:32:05 AM PDT by Pukin Dog (Sans Reproache)
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