Posted on 06/16/2022 1:02:17 PM PDT by dennisw
Don't read this if you're vaccinated A powerful new paper in Science magazine suggests the vaccines are useless if not harmful against Omicron
mRNA Covid vaccines offer essentially no defense against Omicron only months after a booster shot, according to a major new study from British researchers.
Both antibody and T-cell protection are nearly non-existent, the scientists found.
In an even more worrisome development, when vaccinated but previously uninfected people suffer breakthrough Omicron infections, their T-cell response is biased toward earlier versions of Sars-Cov-2 - not to the Omicron variant that has actually infected them.
In other words, the mRNA shots appear to permanently wrongfoot the immune systems of people who receive and bias them toward producing T-cells to attack variants that no longer exist - even though they never were infected with those variants at all.
The T-cell problems are particularly surprising and worrisome.
While antibodies are the first line of defense against infection and try to clear the virus from the bloodstream, T-cells are the crucial second line. They attack and destroy infected cells and also work with other parts of the immune system to produce more and better targeted antibodies later.
Vaccine advocates have claimed endlessly that mRNA-generated T-cells help keep people from becoming severely ill with Covid even after frontline antibody protection against infection disappears.
This study suggests that supposed protection may be a myth, and the low death rates from Omicron are simply a result of Omicron’s general lack of virulence in vaccinated and unvaccinated people alike.
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The study also provides additional evidence that the way the mRNA shots work may leave vaccinated people even more vulnerable to infection and reinfection over time.
The jabs cause people to make one type of coronavirus antibodies. But the study suggested the immune system’s ability to beat the virus also depends on other antibodies - and the shots hamper the production of those.
Scientists have been loathe to admit, much less discuss, the potential long-term problems that mRNA vaccine suppression of broad antibody production may cause.
In this case, though, the authors were concerned enough to acknowledge the issue. They wrote that overall immunity may benefit from parts of the coronavirus that are “exposed only during infection.” Even so, they buried that warning in highly technical language deep in the paper, a sign of the political sensitivities that surround any criticism of the vaccines.
SOURCE
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The prestigious journal Science published the paper, which is based on analysis of antibodies and B- and T-cells in a group of British healthcare workers whom the researchers have followed since March 2020.
The researchers were focused primarily on Omicron’s potential to cause reinfections in vaccinated people who had already been infected with earlier variants of Covid. But they also examined its potential to cause first-time infections in previously uninfected but vaccinated people. Those are the findings that are most interesting for anyone interested in vaccine failure.
Unfortunately but unsurprisingly, the scientists did not look at the immune responses of anyone who was not vaccinated - with or without previous infection. Thus the paper offers no direct comparison of the way Omicron may affect antibody and B- and T-cell responses in vaccinated and unvaccinated people.
Why didn’t the researchers include unvaccinated people? Maybe because nearly all British adults are vaccinated and most boosted, so the authors wanted to concentrate on the risks Omicron poses to vaccinated people.
Or maybe because they worried about what they’d find if they directly compared the two groups.
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Nonetheless, the paper shows clearly that vaccinations and booster doses offer at most a few weeks of protection against Omicron.
None of the “triple-vaccinated, infection naive” people the researchers studied had antibodies able to neutralize Omicron within 14 weeks after the third dose. And the researchers found a T-cell response to Omicron in only 1 of 10 people who had been triply vaccinated but not previously infected.
In addition, the researchers found that a group of previously uninfected but vaccinated people who then became infected with Omicron had a much stronger T-cell response to earlier variants.
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As is typical with papers that present findings this damning, the researchers did not explicitly draw the most worrisome conclusions their data suggests.
But they did openly suggest the fact that the immune response in vaccinated people is biased toward earlier coronavirus variants rather than Omicron even in people who weren’t infected with those earlier variants could help explain “frequent B.1.1.529 (Omicron) reinfections with short time intervals between infections are proving a novel feature in this wave.”
Less clear is what, if anything, anyone can do about this imprinting. The authors noted that efforts by vaccine makers to produce newer mRNA shots that cause the body to produce the Omicron spike have largely failed to overcome the problem, probably for the same reason - the initial imprinting is too strong.
In the meantime, though, Omicron remains relatively mild. As long as it does not mutate to become more dangerous, vaccine advocates can continue to pretend that the billion-person clinical trial of 2021 is not ending catastropically.
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I work with several “wokesters”, who have all been vaccinated and boosted as many times as was available. One of them has had covid 5 times now. Fortunately for me, I have the natural antibodies and t cells from a case of covid that I survived.
“their T-cell response is biased toward earlier versions of Sars-Cov-2 - not to the Omicron variant that has actually infected them. “
Flu shots. You are protected against last year’s strain. Great if you do time travel.
“Flu shots. You are protected against last year’s strain. Great if you do time travel.”
Last year’s strain—in the Southern Hemisphere—so you need both time travel and physical travel.
;-)
I wonder if this kind of thing is a factor in the surge in other viruses (flu etc.) noted in another thread? Instead of a swift and robust immune response that knocks off these other viruses, people are subject to them getting "ahead of" their immune systems because the immune system only has one big hammer in it's toolbox now - going after those original covid variants. A delayed or less effective response (due to the early covid variant bias) might be giving these other viruses a foothold, resulting in out of character infection rates for this time of year.
I am so screwed.
Don't ask, don't tell.
How sciencey!
Doesn’t mention J and J. Wonder how that fits in.
In other words, the mRNA shots appear to permanently wrongfoot the immune systems of people who receive and bias them toward producing T-cells to attack variants that no longer exist - even though they never were infected with those variants at all.
—I wonder if this kind of thing is a factor in ...
No, it’s nonsense. Don’t get me wrong, the vaccines don’t work.
But that quote is nonsense and gibberish.
No!!! They told me it was safe and effective. You’re saying they lied???
I scanned the article looking for the name of the study so I could go to the source and see what it really said.
Huh, they didn’t provide it.
The comments at the end of the article are very enlightening/entertaining!
The Science article is here:
I scanned the article looking for the name of the study so I could go to the source and see what it really said.
**********************
The link was in the article, but I had to dig for it..
https://www.science.org/doi/10.1126/science.abq1841?cookieSet=1
You didn’t scan good enough. Its there. Here it is.
https://www.science.org/doi/10.1126/science.abq1841
Given the accuracy and time frames I've found it more credible than not. For example reports of the variant that caused terrible sore throats start to show up here.
Also many folks record their vax status/# of vaccinations.
A common theme is "I got it and I'm so depressed."
I recommend the forum for anyone going through it. Very useful and interesting anecdotal information.
As my wife and I went through it, I frequently showed her reports from here and we were both able to say "Wow, we did great compared to that..."
Nope. Not vaccinated but I did recommend it to my elderly mother who took medications which would have mitigated any adverse clotting issues.
I thought it was a crime to publish heresy.
What’s up with all these negative vibes?
Ping
Same here. Survived the omnicron, now double and triple faxed are getting sick all around me, mask free.
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