Omega-3s have potential to counteract THC effects on fetal development, study finds

Medical Xpress / University of Western Ontario / Scientific Reports ^ | April 1, 2025 | Cynthia Fazio / Kendrick Lee et al

[ConservativeMind]

Previous studies show exposure to Tetrahydrocannabinol (THC)—the main psychoactive component in cannabis—while in utero can lead to lower birth weight and potential heart complications in newborn animal offspring. For the first time, researchers have found a potential way to prevent those effects.

A recent study is the first to uncover a potential intervention to remedy the decline in birth weight and compromised heart health in offspring due to THC exposure in utero.

Using rat models, the researchers found heart deficits associated with THC were counteracted by Omega-3 supplementation. In this study, researchers were able to replicate the results from a 2019 study in which they demonstrated exposure to THC decreases stroke volume (volume of blood pumped out from the left ventricle), cardiac output (amount of blood your heart pumps out per minute) and ejection fraction (amount of blood your heart pumps each time it beats) in rat offspring.

"When we gave the animal models an Omega-3 diet during pregnancy and for three weeks postpartum, we found it prevented low birth weight outcomes," said Hardy, the study's lead author and professor in the departments of obstetrics and gynecology and physiology and pharmacology. "More importantly, it prevented the early decrease in cardiac function."

According to Hardy, an Omega-3 diet consists of two important fatty acids, DHA and EPA, which play key roles in supporting fetal growth and heart health. Omega-3 has been proven to be a beneficial supplement during pregnancy in preventing gestational diabetes and protecting fetal development. It's also a feasible intervention as Omega-3 is widely accepted and available.

"These results were promising as they show that it is possible to prevent those long-term adverse outcomes in the offspring," said Lee.

[ConservativeMind]

Providing Omega-3s with DHA and EPA fatty acids to mothers rescued THC-induced heart damage and low birth weight in their newborns, in an animal study.

[ConservativeMind]

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[Paal Gulli]

Note to self:
Next time you’re pregnant, dose-up on Omega-3s before firing up that spliff.

[Fungi]

The easy way would be not to smoke during pregnancy. Did any “expert” think o that?

[gundog]

”Far out, man. But, if I could remember to take pills, I wouldn’t get pregnant.”