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Psilocybin shows promise as new treatment for OCD and Tourette's syndrome, finds study
Medical Xpress / Hebrew University of Jerusalem / Molecular Psychiatry ^ | Oct. 29, 2024 | Michal Brownstien et al

Posted on 11/13/2024 2:53:19 PM PST by ConservativeMind

A study led by Prof. Bernard Lerer shows promising results for using psilocybin, a psychedelic compound, as a potential treatment for obsessive-compulsive disorder (OCD) and Tourette's syndrome.

The research provides significant insights into the benefits of psilocybin for managing symptoms similar to those experienced by people with OCD and Tourette's syndrome.

The study included 50 genetically modified mice that displayed excessive grooming and anxiety, similar to human OCD behaviors and head-body twitches similar to tics suffered by patients with Tourette's syndrome.

These mice were randomly given either a single injection of psilocybin, a psychedelic mushroom extract, or a placebo. Raters, unaware of which treatment each mouse received, evaluated the effects at several points over a three-week period.

Mice treated with psilocybin showed a 14.60% decrease in excessive grooming, while those receiving the mushroom extract saw a 19.20% reduction, compared to a significant increase of 118.71 in grooming in the placebo group. The study also observed reductions in other symptoms like tic-like movements and anxiety, with the mushroom extract showing greater benefit in its effect on anxiety. Additionally, the positive effects from a single treatment lasted up to seven weeks in some mice.-0

"Understanding that over 40% of OCD patients don't find relief with current treatments, our findings are crucial as they suggest a new way to help these individuals," Prof. Lerer noted.

"We look forward to advancing to human trials and further exploring how these treatments can provide long-term benefits. The effects observed on tic-like head and body twitches raise the previously unreported possibility that psilocybin may be effective in patients with Tourette's syndrome."

This research highlights the potential of psilocybin and similar substances in treating psychiatric conditions and supports ongoing efforts to discover new, effective mental health therapies.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
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To: Fester Chugabrew

It was ok, until I woke up in the zoo with a belly full of baby springbok.


21 posted on 11/13/2024 5:37:15 PM PST by CTyank
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To: ConservativeMind

Unfortunately, I spent all my time carefully sorting the mushrooms by size and color instead of consuming them to cure my OCD.


22 posted on 11/13/2024 5:41:27 PM PST by KarlInOhio (7/13/2024:The day the Democrats and their SA chose assassination as their primary political tool.)
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To: Fester Chugabrew

A local talk show host said that you are only experimenting with drugs if you are wearing a white lab coat and have a clipboard to record your observations. Otherwise you’re just getting stoned.


23 posted on 11/13/2024 5:43:38 PM PST by KarlInOhio (7/13/2024:The day the Democrats and their SA chose assassination as their primary political tool.)
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To: little jeremiah

I worked in an animal research facility throughout Trump’s first term. There was no ‘stop’ on using animals in research.

The most common animal used in research is the mouse.

(I bet you’d have no problem killing mice, if you had an infestation. Research mice are treated much better than you’d treat them in your house.)


24 posted on 11/13/2024 6:22:43 PM PST by Jamestown1630 ("A Republic, if you can keep it.")
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To: Right Brother

I had a psilocybin experience back in the sixties. Lovely stuff and not at all addictive. If someone knocked on my door and offered me more, I’d take it.


25 posted on 11/13/2024 7:01:47 PM PST by Veto! (Kamalala Sucks Rocks)
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To: Jamestown1630

I hope they don’t experiment on cats. Or dogs. Pets are made to love.


26 posted on 11/13/2024 7:03:28 PM PST by Veto! (Kamalala Sucks Rocks)
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To: Veto!

They’re used when another animal model won’t do the job.

Would you want your sick pet treated with a drug that hadn’t been tested?

If you’ve ever loved a pet that became ill, and you took it to a vet, you’d better hope that any therapy the vet prescribes has been tested and proved to work properly.


27 posted on 11/13/2024 7:19:43 PM PST by Jamestown1630 ("A Republic, if you can keep it.")
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To: Veto!
"I hope they don’t experiment on cats. Or dogs. Pets are made to love."

If you truly loved them you'd leave them wild. Only one half of the relationship benefits from keeping a pet. Especially when they cut out healthy reproductive organs to spare the human master (didn't slaves have "masters"?) from the consequences of the animal's natural sexual instincts.

28 posted on 11/13/2024 9:24:14 PM PST by Paal Gulli
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To: ConservativeMind

Don’t know for certain that’s what they’re doing but microdosing involves administering several times less than would produce even a mild hallucinogenic experience and it still promotes the brain wiring new neural pathways.

Of course none of that matters to so many of the Freepers who already know everything about everything and only post here to to mock those who do not.


29 posted on 11/13/2024 9:27:23 PM PST by Paal Gulli
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