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New shingles vaccine could reduce risk of dementia
Medical Xpress / University of Oxford / Nature Medicine ^ | July 25, 2024 | Maxime Taquet et al

Posted on 08/01/2024 8:01:34 PM PDT by ConservativeMind

A study of more than 200,000 people by researchers found at least a 17% reduction in dementia diagnoses in the six years after the new recombinant shingles vaccination, equating to 164 or more additional days lived without dementia.

The benefit was seen in both sexes but was greater in women, and the findings suggest that the recombinant shingles vaccine may have additional value in terms of protection against dementia.

Shingles is a painful and serious condition afflicting many elderly people. It is caused by the Herpes zoster virus that can flare up in people who previously had chicken pox. After the introduction of a vaccine against shingles (Zostavax) in 2006, several studies have suggested that the risk of dementia might be lower in people who had received the vaccine, although results were not conclusive.

In many countries, Zostavax has now been withdrawn and replaced by a much more effective vaccine (Shingrix).

In the study, researchers used the U.S. TriNetX electronic health records network. In the U.S., there was a switchover between Zostavax and Shingrix in October 2017. This allowed the researchers to compare the risk of dementia in the six years following Shingrix compared to otherwise similar people who had received Zostavax. More than 100,000 people were in each group. Shingrix was also compared to people who had received vaccines against other infections (flu and tetanus, diphtheria, and pertussis).

Shingrix was associated with 17% lower risk of dementia than Zostavax, and 23–27% less than with the other vaccines. This equates to 5–9 more months lived without dementia for those who had been given the Shingrix vaccine compared to the other vaccines. The beneficial effects were present in both sexes but greater in women than in men.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: chickenpox; dementia; herpes; herpeszoster; shingles; shingrix; vaccines; wod; zostavax; zostavix
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To: steve86

Thanks, Steve! Appreciate that.


21 posted on 08/01/2024 10:37:17 PM PDT by ProtectOurFreedom (“When exposing a crime is treated like a crime, you are being ruled by criminals” – Edward Snowden)
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To: ConservativeMind

Noping out


22 posted on 08/01/2024 10:39:02 PM PDT by Secret Agent Man (Gone Galt; not averse to Going Bronson.)
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To: ProtectOurFreedom

That elevation gain should have been 800’. I thought it felt like more than 600!


23 posted on 08/01/2024 10:41:21 PM PDT by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: ConservativeMind

I had shingles in 2007. 4 horizontal lines across my upper torso. I tried to “be a man” and endure the pain for 3 days, but could not take it any more. Doc took one look, said”Yep, it’s shingles!”

At least the pain killer was effective, and I could not drive,so I got 10 days off work.

Actually, I could drive, but my attention wandered all over. Look, a bird! Leaves blowing in the wind! Flowers! Uh oh, a car. Birds! Hey, I just passed my building! So, I didn’t drive.


24 posted on 08/01/2024 10:42:09 PM PDT by jimtorr
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To: steve86

The South Bay Area has hundreds of trails ranging from flat by the Bay to 2,500 foot climbs on the mountains surrounding the area. There’s so much to choose from it can be tough picking one out. I’m headed back to North Idaho in a week or two, then we have a trip to the northern Canadian Rockies the first week of September. Looking forward to that!


25 posted on 08/01/2024 10:42:28 PM PDT by ProtectOurFreedom (“When exposing a crime is treated like a crime, you are being ruled by criminals” – Edward Snowden)
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To: jimtorr

There’s nothing worse than clothing rubbing against a shingles spot. Excruciating!


26 posted on 08/01/2024 10:43:25 PM PDT by ProtectOurFreedom (“When exposing a crime is treated like a crime, you are being ruled by criminals” – Edward Snowden)
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To: ProtectOurFreedom

Avoid the Jasper area. You probably wouldn’t be welcomed right there now anyway .


27 posted on 08/01/2024 10:54:00 PM PDT by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: ConservativeMind

I had an adverse reaction to Shingrex and a permanent touch of vertigo as a constant reminder.


28 posted on 08/02/2024 12:51:50 AM PDT by jacknhoo (Luke 12:51; Think ye, that I am come to give peace on earth? I tell you, no; but separation.)
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To: ConservativeMind
Too Late!


29 posted on 08/02/2024 3:13:25 AM PDT by Apparatchik (Русские свиньи, идите домой!)
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To: ConservativeMind

If you take valtrex immediately at onset it is suppose to help.if you wait..I don’t know how long..benefit lessens

Makes sense because it fights herpes.


30 posted on 08/02/2024 3:20:31 AM PDT by RummyChick ( )
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To: ConservativeMind

I took both shingles vaccines in 2020. I refuse to get those buggers


31 posted on 08/02/2024 4:05:59 AM PDT by napscoordinator (DeSantis is a beast! Florida is the freest state in the country! )
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To: napscoordinator

I got my shingles vax in 2022 after seeing two friends from church get it. I think it will be the last vax I ever get.


32 posted on 08/02/2024 4:11:18 AM PDT by circlecity
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To: roving

I’m done with all vaccines.
~~~~~~~~~~~~~~~~~~~
I never did buy into EGTs... but wouldn’t go quite as far as ‘all vaccines’ when that refers to real vaccines as opposed to the fake ones. Having said that, it’s been 30 years since I’ve had one. I have considered the shingles vaccine since I have a brother who had it very bad.


33 posted on 08/02/2024 4:19:05 AM PDT by hecticskeptic
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To: ConservativeMind

If you see a provider within 24 hours of onset of symptoms there are therapeutics that can work very well.

Most people who get shingles are one and done.

For people with weakened immune systems, a shingles vaxx might make sense, but only with informed consent.

I don’t know anyone who’s been offered a shingles vaxx who’s been given what I’d consider informed consent.


34 posted on 08/02/2024 4:24:25 AM PDT by mewzilla (Never give up; never surrender!)
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To: TexasGator

I had it in my eye and on the side of my face about 15 years ago. It was scary.


35 posted on 08/02/2024 4:30:57 AM PDT by yukong
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To: TexasGator

I had it in my eye itself as well as around my eye and side of my face. My doc sent me to an ophthalmologist. He was very concerned and said it could lead to blindness and put me on oral and topical meds. Thankfully it cleared up. But boy it was painful.


36 posted on 08/02/2024 4:34:15 AM PDT by yukong
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To: steve86

“The most popular hiking hill/trail we have here is 600 feel elevation gain in exactly one mile. It is reasonably steep for casual walkers.”

So I guess you don’t see any Secret Service Agents on the trail.


37 posted on 08/02/2024 4:35:52 AM PDT by MayflowerMadam (It's not as if Biden has the nuclear codes or anything. 😳)
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To: jimtorr

“4 horizontal lines across my upper torso.”

Was it across the whole upper torso, or just right or left side? When Hubby had it, it was only on half of his body. Same for my aunt.


38 posted on 08/02/2024 4:37:29 AM PDT by MayflowerMadam (It's not as if Biden has the nuclear codes or anything. 😳)
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To: circlecity

That’s one vax I will get every ten years or how ever long they last. I’m dumbfounded by those who refuse to get that one. I fought for mine. I totally understand not wanting to get the Covid vax or other ones. But the shingles vaccine? That’s a mystery.


39 posted on 08/02/2024 4:39:41 AM PDT by napscoordinator (DeSantis is a beast! Florida is the freest state in the country! )
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To: napscoordinator

No mystery.

Read the boilerplate that comes with the vaxx.

When recurrence rate is running around 5% to 12%, when the repeats tend to come in folks with impaired immune systems, when there are very good antivirals that work if started soon after onset, when the vaxx doesn’t provide complete protection and comes with a laundry list of adverse effects, sone serious...

See where I’m going with this?

Seems to me that for most folks, for most of their lives, this is another vaxx they might want to think about giving a miss.

It’s called informed consent for a reason.


40 posted on 08/02/2024 5:12:30 AM PDT by mewzilla (Never give up; never surrender!)
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