Posted on 06/28/2024 10:53:13 PM PDT by ConservativeMind
Neurodegenerative diseases (NDDs) result in irreversible damage to the brain and nervous system. Research into these diseases typically focuses on the brain, but mouse studies from the last few years suggest that the microbiome plays a role in the onset and progression of some NDDs, as well.
Those researchers report a new link in humans between a metabolite produced by gut microbes and three NDDs. Their analysis suggests that the metabolite DHPS (2,3-dihydroxypropane-1-sulfonate) may help answer critical questions about how sulfur metabolism pathways can connect the microbiome to these diseases.
DHPS has not previously been detected in people, and the researchers noted that metabolites produced by gut microbes in patients with NDDs might offer valuable clues.
The researchers undertook the new study to identify distinct bacterial and metabolite profiles of the gut microbiome in people diagnosed with one of three NDDs: amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), and Parkinson's disease (PD). To capture data on early-stage disease, they collected stool samples.
In all three disease groups, they found links to Bilophila and Desulfovibrio bacterial taxa, which play a role in synthesizing and degrading DHPS. Those increased levels of Bilophila corresponded to the observation that patients with AD, ALS and PD had lower abundance of DHPS in stool samples, compared to healthy subjects.
Bilophila can degrade DHPS into hydrogen sulfide, and the accumulation of hydrogen sulfide has been implicated in the dysfunction of mitochondria, which is known to contribute to NDDs. Hydrogen sulfide is linked to known NDD hallmarks, including inflammation, oxidative stress and gut dysbiosis.
The authors suggested that the new study flags DHPS as a "missing link" in our current understanding of the mechanisms of how NDDs are linked to sulfur metabolism, mitochondrial dysfunction and neuroinflammation.
(Excerpt) Read more at medicalxpress.com ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383351/
C. butyricum, Bifidobacterium, and Lactobacillus, including L. acidophillus, helped.
is this what happened to Biden?
LMAO
Not sure if this is a place do... But I love my fermented veggies. I can feel unwell if I don’t get my fermented sauerkraut or pickles, or kvass, or anything else I stuff in my pickle jars.
FYI.... these are lactobacillis fermented veggies with nothing more than a 3% salt brine and a few months of sitting in my cool basement. They are absolutely delicious pickles.
Bkmk
The sulfonate compound 2,3-dihydroxypropane-1-sulfonate (DHPS) is one of the most abundant organic sulfur compounds in the biosphere. DHPS derived from dietary intake could be transformed into sulfide by intestinal microbiota and thus impacts human health. However, little is known about its sulfur transformation and subsequent impacts in marine environment.
https://pubmed.ncbi.nlm.nih.gov/34425483/
gut bacteria is the cutting edge of medicine imo. It controls everything, even personality. It can affect the brain and everything else. That is why it is such a crime against humanity that these mega corps have poisoned the food supply with artificial garbage and chemicals to replace natural foods that our body needs.
So foods we should concentrate on?
Kefirs and yogurts, but probiotic supplements can have many more varieties of bacteria.
My “Ice Cream” is plain kefir poured over frozen blueberries.
bkmk
Thanks.
Can you tell me how much salt to mix with how much water to get a 3% brine? I just bought a watermelon and thought I could make rind pickles.
My husband who died of Alzheimers had very stinky farts when we were firs married. When we started eating yoghurt the stinkies went away. Also, even then when he was in his late thirties his mind would occasionally do a very short brain freeze. My mother wondered if he was having very short petit mal episodes. He had to retire at 66 because his job had been moved to a new location with some new support personnel and he could not make the adjustment (remembering all this new stuff). He died at age 75. His mother also died of Alzheimers.
So I wonder if his early bowel state was indicative of the future Alzheimers? If so, did the addition of yoghurt not help the problem, even though the sulfur part of the gas he produced was considerably reduced? One other thing about his Alzheimers, he remained physically capable until a month before he died, since I was giving him a number of supplements. He could only remember new information for about 15 seconds, but he could walk the 3 blocks to the grocery store and help carry the grocery bags home. Two months before he died I would have to take the bags out of his hands so he could use the handrail climbing the 6 steps to the door.
Place empty jar on you scale. Make note how much it weighs or tare the scale to zero. Add the rinds. Add hot water to cover everything. Multiply the combined weight of the rinds and water by .03 or .025 for a little less salt. Add the salt. Place a pickle weight on top to hold everything under the brine. Screw on a vented one way lid. And wait a couple weeks, or longer if you like really sour pickles. It will bubble and turn cloudy but that’s the bacteria working.
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