Posted on 06/21/2024 7:05:25 PM PDT by ConservativeMind
A study has revealed a link between gut microbiota and Parkinson's disease (PD). The researchers found a reduction in the gut bacteria of genes responsible for synthesizing the essential B vitamins B2 and B7.
They also identified a relationship between the lack of these genes and low levels of agents that help maintain the integrity of the intestinal barrier. This barrier prevents toxins from entering the bloodstream, which causes the inflammation seen in PD. Their findings suggest that treatment with B vitamins to address these deficiencies can be used to treat PD.
In ideal conditions, gut microbiota produce SCFAs and polyamines, which maintain the intestinal barrier that prevents toxins entering the bloodstream. Toxins in the blood can be carried to the brain where they cause inflammation and affect neurotransmission processes that are critical for maintaining mental health.
They observed a decrease in the bacterial genes responsible for the synthesizing of riboflavin (vitamin B2) and biotin (vitamin B7) in patients diagnosed with PD. Riboflavin and biotin, derived from both food and gut microbiota, have anti-inflammatory properties, which may counteract the neuroinflammation seen in diseases like PD.
B vitamins play crucial roles in the metabolic processes that influence the production and functions of short-chain fatty acids (SCFAs) and polyamines, two agents that help maintain the integrity of the intestinal barrier, preventing toxins entering the bloodstream. An examination of fecal metabolites revealed decreases of both in patients with PD.
The findings indicate a potential explanation for the progression of PD. "Deficiencies in polyamines and SCFAs could lead to thinning of the intestinal mucus layer, increasing intestinal permeability, both of which have been observed in PD," Nishiwaki explained.
"This higher permeability exposes nerves to toxins, contributing to abnormal aggregation of alpha-synuclein, activating the immune cells in the brain, and leading to long-term inflammation.
(Excerpt) Read more at medicalxpress.com ...
Soluble fiber helps bacteria make SCFAs.
The authors suggest simple supplementation with those two B vitamins might be of great help, but, in my estimation, the benefit from bacteria making SCFAs and polyamines may go beyond just B vitamin benefits, instead, helping to rebuild the mucus barrier lining the intestines.
I have previously posted other study writeups on the benefits of soluble fiber.
Which soluble fiber?
Interesting! Hopefully my Vit B Complex is helping.
hmm, this ‘Microbiota’ stuff- dunno how legit it is- but it might just turn into some real cures for certain issues- maybe even many issues- hope it pans out
What about fermented foods such as sauerkraut?
Here we go again.
Parkinson’s, ALS, MS, Huntington’s are easily treated and 100% reversible.
But apparently, I’m the only one with a computer that comes equipped with a search engine.
Sauerkraut has fiber which helps support a diverse biome.
Buy the real stuff though that is naturally fermented with lactobacillus, not the fake stuff made with vinegar. Or make it your self—cabbage +salt=sauerkraut.
Thanks for posting.
Husband just diagnosed with Parkinson’s, over abundance of information online. Would love to know how to treat and reverse.
Dr Joel Wallach; Parkinson’s is 100% a nutritional issue, and that includes absolutely gluten-free diet until he recovers
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