Posted on 04/14/2024 8:37:14 PM PDT by ConservativeMind
Regular aerobic exercise later in life prevents genomic instability characterized by DNA damage and telomere dysfunction, according to a study.
"These new findings will greatly impact our understanding of the mechanisms of how aerobic exercise improves vascular health at the level of genomic stability," says Jisok Lim, Ph.D.
Late-life exercise used to be thought of as ineffective. However, existing studies indicate aerobic exercise later in life lowers the risk of cardiovascular disease-related mortality. Yet, specific factors contributing to this effect have not been completely understood.
Researchers examined whether regular exercise with aging may prevent DNA damage and telomere dysfunction. Telomeres are protective caps at the end of chromosomes. In this study, exercise was shown to be especially helpful in cells that come in direct contact with blood flow (endothelial cells). The benefits of aerobic exercise are particularly noticeable in the aortic regions less prone to atherosclerosis due to favorable blood flow patterns.
During the four-month study, 15 male mice were given access to a voluntary running wheel. The mice were assigned to high-, moderate- and low-running groups based on their consistent running distances. Aortic tissues exposed to different blood flow patterns were collected to evaluate DNA damage and telomere function. The findings suggest the increased level of exercise later in life has a beneficial impact on DNA damage and telomere dysfunction.
There are many contributing factors to arterial aging. The driving factor among them is DNA damage. While more study in this area is needed, physiologists hope these findings lay the groundwork for improving human health in the future.
"By revealing the varied responses of aortic regions experiencing different blood flow patterns and cell types to aerobic exercise, this research will provide a firm ground on a detailed and customized approach to interventions for cardiovascular health," said Jisok Lim, Ph.D.
(Excerpt) Read more at medicalxpress.com ...
We walk 3-4 miles a day 6 days a week and I use the rubber workout bands 3 days a week - wife is 74 and I’m 72 and the workouts are bringing veins back to the surface in my hands and forearms so they don’t have to search to get blood these days...
Good for you all!!
I like your term "athletic active." That's me. At three months from hitting the big "eight zero" mark, I'm the same. I walk three to five miles every day, eat primarily a plant food diet, and have been on a 1000-calorie-a-day diet for almost seven years. Plus, I still work full-time at my own business. It keeps me going.
Wow. That is great.
Thanks.
Wow...that makes me more negayive on vaxxes...when I was hospitalized last August to have Antibiotic IVs because my cat “injected” me with strep (one claw got into me) they asked if I was up to date on Tetanus. I lied.
Do you not eat ANY chicken, fish, beef, pork?
I'll have a small helping of chicken perhaps once a week and less frequently fish. I very seldom eat beef or pork, though. I get what little protein I need primarily from a protein shake, but I don't overdo it on protein. 50gms/day for my body size is adequate.
My diet consists primarily of raw veggies and nuts, with a decent helping of sweets to satisfy my cravings. I avoid processed foods like the plague. I do go off the wagon eating out about once a week -- but usually salads.
It's a crazy diet, I know. But unlike most people, I eat to live, not live to eat.:-)
I actually started this diet regimen seven years ago due to low to no kidney function. It has helped dramatically. In fact, I credit it with getting me off of dialysis, with no kidney transplant, that lasted three years. It also keeps me healthy, along with a good exercise regimen (like you all).
As I say...everyone is different. Protein seems to be my main requirement...too many carbs in nuts so I cut back to pumpkin seeds only...I am playing around with my diet again. I do know as we age we need LESS calories. :*))
We sure are all different. For weight control, the primary consideration is total calories per day. For me, at 1000 calories per day, I really don't worry about fats, sweets, or carbs solely for weight control. I certainly am concerned about nutrition, and my primarily veggie and nut diet seems to do the trick.
By the way, my nuts are almonds, and a generous handful is less than 2 gms. So, no big impact.
Along with the many doctors I see, I'm a firm believer that exercise and diet are the keys to a healthy life and aging well. The older we get the more important it becomes.
I’ve discovered that doing a little, consistently really works for me. I don’t make it difficult — 15 minutes on the recumbent bike, 20 minutes of core exercises involving small hand weights (no sit-ups or crunches) every day without fail (including holidays) and 20 minutes of free weights on Mondays, Wednesdays and Fridays (dumbells, barbell on the weight bench) — has truly made a difference for me. I’ve lost 55 pounds in about nine months, and look better at 64 than I did at 46. Of course I have a weight bench and a bike down in the basement and actually have the time to put into it, and can skip the gym. I never had time for this while I was working full time and greatly sympathize with those who try to fit it in with their work schedules. It always daunted me.
I can’t trust vaccines anymore, and stopped all Flu vaxes.
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I know what you mean. I’m afraid to take the shingles vaccine although I’ve been told that having shingles is a nightmare.
But not only vaccines, other medications which we take for granted can cause adverse reactions. My audiologist said aspirin is the drug that most often causes tinnitus; I had no idea!! And I just read an Epoch Times article saying that people who take a class of antibiotics called fluoroquinolones, such as Cipro, have experienced tendon ruptures. It has a cumulative effect. I’ve taken Cipro in the past but had no idea of the risk.
It seems like avoiding everything is best, if one can.
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