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Large stroke trial finds intensive blood pressure lowering after clot removal worsens recovery (“Significantly worse”)
Medical Xpress / George Institute for Global Health / World Stroke Congress / The Lancet ^ | Oct. 28, 2022 | Professor Craig Anderson

Posted on 10/30/2022 8:36:42 AM PDT by ConservativeMind

A large stroke trial has shown that intensive blood pressure lowering after clot removal worsens recovery, stopped early due to the significance of the findings.

Professor Craig Anderson said the rapid emergence of this effect suggested the more aggressive approach was compromising the return of blood flow to the affected area.

"Our study provides a strong indication that this increasingly common treatment strategy should now be avoided in clinical practice," he said.

Around 85 percent of strokes are ischemic strokes, caused by the loss of blood flow to an area of the brain due to a blockage in a blood vessel, leading to a loss of neurological function.

Endovascular thrombectomy is an increasingly used non-surgical treatment for ischemic stroke, in which microcatheters or thin tubes visible under X-rays are inserted into the blood clot to dissolve it.

"A potential downside of this now widely used and effective treatment is that the rapid return of blood supply to an area that has been deprived of oxygen for a while can cause tissue damage known as reperfusion injury," said Professor Anderson.

"This has resulted in a shift in medical practice towards more intensive lowering of blood pressure after clot removal to try and minimize this damage, but without evidence to support the benefits versus potential harms."

Patients in the more-intensively treated group had significantly worse scores on the scale compared to those allocated to those treated less intensively.

Compared to the less-intensive group, they had more early brain tissue deterioration and major disability at 90 days but there were no significant differences in brain bleeds, mortality, or serious adverse events.

Patients who had their blood pressure more intensively controlled also rated their quality of life as significantly worse due to limitations on their physical abilities resulting from their stroke.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: bloodclots; bloodpressure; brain; neurological; stroke
More brain tissue deterioration and major disabilities at the 90 day point, but not more deaths.
1 posted on 10/30/2022 8:36:42 AM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 10/30/2022 8:37:27 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Imagine if such studies were conducted about Covid, and Covid shots.

What knowledge we could assimilate. What help it would be to mankind.

I question whether it will ever happen.

Imagine stopping an experiment because there are too many negative side effects! I never thought I’d see the day, in the USA, where we would not.


3 posted on 10/30/2022 8:42:03 AM PDT by Persevero (You cannot comply your way out of tyranny. )
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To: ConservativeMind

How do they rule out damage caused by ischemic cascade...?


4 posted on 10/30/2022 8:47:50 AM PDT by mewzilla (We need to repeal RCV wherever it's in use and go back to dumb voting machines.)
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To: Persevero

Happened in ‘77.

The Swine Flu vaxx was pulled after causing fewer than 3 dozen reported deaths and fewer than 500 reported injuries.

Human life meant more then.


5 posted on 10/30/2022 8:49:31 AM PDT by mewzilla (We need to repeal RCV wherever it's in use and go back to dumb voting machines.)
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To: mewzilla

Yes, research was real and medicine was honestly practiced.

Of course it made mistakes; but they were genuine mistakes and measures were taken to correct them.


6 posted on 10/30/2022 8:50:32 AM PDT by Persevero (You cannot comply your way out of tyranny. )
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To: ConservativeMind
Duh.


7 posted on 10/30/2022 8:51:10 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: ConservativeMind

when I had an ischemic stroke a year ago they deliberately kept my blood pressure high for a few days afterward. Stroke wiped out my left side but it has mostly come back.


8 posted on 10/30/2022 8:52:57 AM PDT by HerrBlucher
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To: HerrBlucher

Keep up the excellent recovery! That’s a major comeback.


9 posted on 10/30/2022 9:05:01 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: HerrBlucher

Me, as well. My stroke was in 2013. Took me a year to walk unaided and 2 years to write. 3 years to reliably write legibly.


10 posted on 10/30/2022 9:15:24 AM PDT by FrogMom (Time marches on...)
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To: FrogMom

That is good to hear, maybe there is a chance I’ll be able to play the guitar again, I really miss it!


11 posted on 10/30/2022 9:49:49 AM PDT by HerrBlucher
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To: Persevero

260 Million+ Americans have received covid vaccine shots.
I have not heard of 2.6 million casualties from the vaccine.
Even Biden can calculate that makes the vaccine AT LEAST 99% safe.


12 posted on 10/30/2022 10:37:03 AM PDT by entropy12
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To: ConservativeMind

I thought we already knew this but whatever. Signed, some stupid doctor.


13 posted on 10/30/2022 11:01:24 AM PDT by JusPasenThru (Broken hearts are for…well…you know…)
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To: entropy12

You are right I don’t think there at that many casualties.

I do think there are many with complications that don’t count as casualties. And miscarriages and still births too :(

Anyway.

Covid has less than a one percent fatality rate.

Shots have less than one percent fatality rate.

So why did we spend billions and destroy our economy and freedom and general health. An absolute travesty.


14 posted on 10/30/2022 2:12:31 PM PDT by Persevero (You cannot comply your way out of tyranny. )
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To: Persevero
Covid has less than a one percent fatality rate.

It is far even less for healthy young people under age 50. I would concede mortality was high when covid first arrived, for 2 reasons. No one had immunity for that virus and old people sick with covid were shoved into nursing home where it spread like wild fire. I see no need anymore for any mandates for vaccine from the gov't.

15 posted on 10/30/2022 2:17:23 PM PDT by entropy12
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To: ConservativeMind

This does suggest a possible therapy. There are now some artificial bloods that carry as much as 3x the oxygen of regular red blood cells. While trying to replace a lot of blood with it may cause problems, what about using just a bit *added* to the blood?

The trouble is that while there are a bunch of Oxygen therapeutics out there, some even passing Phase III trials, there is a strong hesitancy to giving them approval instead of leaving them in the limbo of “needs more research.”


16 posted on 10/30/2022 2:17:43 PM PDT by yefragetuwrabrumuy ("All he had was a handgun. Why did you think that was a threat?" --Rittenhouse Prosecutor)
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