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Old Saying About Prostate Cancer Not True When It's Metastatic (80% die from it)
Medscape / JAMA Netw Open ^ | Sept. 2, 2021 | Nick Mulcahy / Ahmed Elmehrath, MD, Omar Alhalabi, MD, Samuel Merriel, MSc, Tanimola Martins, et al

Posted on 10/24/2021 9:17:29 AM PDT by ConservativeMind

Nearly 80% of men with metastatic prostate cancer died from their malignancy, according to a retrospective cohort study.

The findings fill an information gap because, remarkably, "data are lacking" on causes of death among men whose prostate cancer has spread to other sites, say lead author Ahmed Elmehrath, MD.

"It was an important realization by our team that prostate cancer was the cause of death in 78% of patients," said senior author Omar Alhalabi, MD, of University of Texas MD Anderson Cancer Center, Houston, in an email to Medscape Medical News.

The findings represent the near opposite of a commonly held — and comforting — belief about early-stage disease: "You die with prostate cancer, not from it."

That old saying is articulated in various ways, such as this from the Prostate Cancer Foundation: "We can confirm that there are those prostate cancers a man may die with and not of, while others are very aggressive." The American Cancer Society says this: "Prostate cancer can be a serious disease, but most men diagnosed with prostate cancer do not die from it."

However, these commonplace comments do not cover metastatic disease, which is what the authors of the new study decided to focus on.

The majority of these deaths (77.8%) were from prostate cancer, 5.5% were from other cancers, and 16.7% were from noncancer causes, including cardiovascular diseases, chronic obstructive pulmonary disease, and cerebrovascular diseases.

Most of the prostate cancer deaths (59%) occurred within 2 years. The 5-year overall survival rate in the study group was 26%. The deadliness of metastatic disease "reinforces the need for innovations to promote early-stage diagnosis," comment the editorialists. Striking a hopeful note, they also say that "new tests for prostate cancer detection may reduce the proportion of patients who receive a diagnosis at a late stage."

(Excerpt) Read more at medscape.com ...


TOPICS: Health/Medicine
KEYWORDS: prostatecancer
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To: ConservativeMind

The only thing pols and the media care about are things that affect women.


41 posted on 10/24/2021 10:05:47 AM PDT by PghBaldy (12/14 - 930am -rampage begins... 12/15 - 1030am - Obama's advance team scouts photo-op locations.)
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To: hanamizu

Get a PSA test. It might well save your life.


I put my faith in the Great Healer. I am 68. The bible sez the average lifespan is 70 or maybe 80. This life is a mist. I’m not sweating about making it last longer. I take care of this body god temporarily gave me to occupy and leave it at that.

If I get cancer, I’ll not take any of the “ama approved” methods of treatment. There are other methods that actually work. But at my age, fatal illnesses are not a thing to fear. Same goes for my wife, who is six days younger than me.


42 posted on 10/24/2021 10:11:12 AM PDT by cuban leaf (My prediction: Harris is Spiro Agnew. We'll soon see who becomes Gerald Ford, and our next prez.)
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To: Spok

PC is very slow growing. Very slow.

But by the time it goes metastatic, usually into the bladder and lymphs, the cancer becomes fast growning.

A PSA test on a regular basis is a good tattle tale of something is not right.

Frequent nightly urinations is what made me think something had changed and mentioned same to my doc in my annual physical (I was 63 when I was diagnosed with stage 1 PC)

In my case I got external and internal radiation. Outside of the fact my “appendage” glows in the dark now, all is well.


43 posted on 10/24/2021 10:12:04 AM PDT by llevrok (Pronouns: Me/myself/& I)
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To: for-q-clinton
as I have stated, my youngest brother had PC in his early 50's....highly unusual....PC doesn't hit to a lot later in life....

Breast cancer however, can strike and kill very young women, as in their 20's.....not so for PC.....

44 posted on 10/24/2021 10:12:42 AM PDT by cherry
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To: ConservativeMind

As many of you here already know, the Great Frank Zappa died of prostate cancer in 1993. He was only 52 years old.
Frank would have loved the internet. He was very bright and would have quickly mastered the digits and widgits.


45 posted on 10/24/2021 10:17:01 AM PDT by lee martell
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To: gloryblaze

Key word, “if”. That’s what insurance companies depend on us lifting above all else. A life insurance company is betting you are going to live, while you are betting you are going to die.

And the weird “unconscious” event is a stretch. Sure, it could happen, possibly, maybe. But a card in my wallet that clearly says “Don’t involve any transportation service that will charge money for the service” would be welcome in court, should someone try to charge me.


46 posted on 10/24/2021 10:19:13 AM PDT by cuban leaf (My prediction: Harris is Spiro Agnew. We'll soon see who becomes Gerald Ford, and our next prez.)
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To: ConservativeMind

Get your PSA checked.


47 posted on 10/24/2021 10:21:40 AM PDT by arkfreepdom
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To: cuban leaf

That is what all insurance is about. Even if you are not unconscious, but merely unable to move or get up, such as having shattered a hip. Who is going to move you to your bed, and then in and out of it for months? And no one is going to search your wallet before you get to a facility. You’d better tatoo your forehead, “Just leave me to croak or pay my bill.”


48 posted on 10/24/2021 10:27:44 AM PDT by gloryblaze
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To: cuban leaf

A lot of people seem to want to try and live forever, and I don’t see the point.

If I break a leg, I’ll see a doctor.
If I have a bacterial infection, I’ll take an antibiotic.

I actually do get annual check-ups (more or less) but I do not put a lot of emphasis on medical care. I’m not anti-medicine, but it’s not my savior. As you say, the Lord will choose my time.


49 posted on 10/24/2021 10:33:52 AM PDT by ClearCase_guy (Alec Baldwin has killed more people than the Jan 6 protesters. And he will serve less jail time.)
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To: ConservativeMind

Went to have my first one. Never again. They couldn’t finish it. Plus, they didn’t give me enough stuff to put me out. I told them when you come up with a better way, let me know


50 posted on 10/24/2021 10:45:57 AM PDT by roving
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To: A Navy Vet

good for you got 5 yrs on me, mine is always low


51 posted on 10/24/2021 10:49:58 AM PDT by markman46 (engage brain before using keyboard!!!)
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To: blam

WOW every 6 months


52 posted on 10/24/2021 10:50:34 AM PDT by markman46 (engage brain before using keyboard!!!)
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To: cherry

I did a fair amount of research on it more than a decade ago. So some of it has just slipped away from my mind. PSA and Gleason Scores and all that. But as I recall, when examining older men who passed from any cause they found about 80% of them also had PC. It just happens a lot but it usually happens when a man gets older and it tends to grow very slowly so it doesn’t matter for most. It stays localized and grows slowly.

If it happens to occur in a younger man, definitely keep an eye on it. There is a reason why they start checking men at age 50. It’s not necessarily a death sentence - there hasn’t been as much research into treatment as say BC has received - but there have been good advancements in the last 10 or so years.


53 posted on 10/24/2021 10:53:44 AM PDT by monkeyshine (live and let live is dead)
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To: EC Washington

Never seen such evil. So sad.


54 posted on 10/24/2021 10:54:31 AM PDT by FreeperCell
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To: ConservativeMind

Strange. Don’t recall the particulars of dads issue. Nor know his brother’s. Seems to me dad just had a regular urology appt and maybe regular cystoscope? Don’t recall.

But my dad and his brother both lasted 10 years past it. Seems they were successful. Still have to wonder about dads death, though…too quick to be sure but supposedly acute Lymphoma.


55 posted on 10/24/2021 10:57:20 AM PDT by the OlLine Rebel (Common sense is an uncommon virtue./Federal-run medical care is as good as state-run DMVs.)
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To: roving

Your first what? Couldn’t finish what?


56 posted on 10/24/2021 10:58:26 AM PDT by the OlLine Rebel (Common sense is an uncommon virtue./Federal-run medical care is as good as state-run DMVs.)
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To: for-q-clinton
Huh? I have spent $0 on prostitues, but spend thousands upon thousands on taxes.

Glad to hear it, but as a group, men spend billions a year on prostitution in this country alone. That's money that could go into funding the research into prostate cancer.

Your statement makes no sense and is what is wrong with America.

I'll agree all of that money spent on prostitution is a problem, but I'll spell it out for you. 1/10 of the billions spent on prostitution every year would be tens of millions that could be invested in activism and research. That activism is what would bring attention to prostate cancer and result in more research, as it has for breast cancer.

Between funding activism and research and paying for prostitutes, which do you think gets more money from men?

57 posted on 10/24/2021 11:01:45 AM PDT by TwelveOfTwenty (Will whoever keeps asking if this country can get any more insane please stop?)
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To: cuban leaf

Good point.


58 posted on 10/24/2021 11:04:14 AM PDT by thecodont
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To: Empire_of_Liberty

Medicine has been quackery for long before COVID.


Yes. People without contact with the medical system think health workers are wise and angelic.


59 posted on 10/24/2021 11:05:35 AM PDT by TTFX ( )
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To: Spok

It’s a lot more unpleasant than swallowing IP6 first thing in the morning.

I get a PSA test once a year, but I try not to depend on orthodox medicine to keep me alive. They operate to make a profit, not make people healthy.


60 posted on 10/24/2021 11:09:06 AM PDT by devere
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