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Fibromyalgia likely the result of autoimmune problems
Science Daily / King's College London, University of Liverpool and the Karolinska Institute ^ | July 1, 2021 | Dr David Andersson, et al

Posted on 07/02/2021 10:29:10 AM PDT by ConservativeMind

New research has shown that many of the symptoms in fibromyalgia syndrome (FMS) are caused by antibodies that increase the activity of pain-sensing nerves throughout the body.

The results show that fibromyalgia is a disease of the immune system, rather than the currently held view that it originates in the brain.

The study demonstrates that the increased pain sensitivity, muscle weakness, reduced movement, and reduced number of small nerve-fibres in the skin that are typical of FMS, are all a consequence of patient antibodies.

The researchers injected mice with antibodies from people living with FMS and observed that the mice rapidly developed an increased sensitivity to pressure and cold, as well as displaying reduced movement grip strength. In contrast, mice that were injected with antibodies from healthy people were unaffected, demonstrating that patient antibodies cause, or at least are a major contributor to the disease.

Furthermore, the mice injected with fibromyalgia antibodies recovered after a few weeks, when antibodies had been cleared from their system. This finding strongly suggests that therapies which reduce antibody levels in patients are likely to be effective treatments. Such therapies are already available and are used to treat other disorders that are caused by autoantibodies.

Current estimates suggest that at least 1 in 40 people are affected by FMS worldwide (80% of which are women) and is commonly characterised by widespread pain throughout the body, as well as fatigue (often referred to as 'fibro fog') and emotional distress. It most commonly develops between the ages of 25 and 55, although children can also get it.

Dr Andreas Goebel said, "I expected that some fibromyalgia cases may be autoimmune. But David's team have discovered pain-causing antibodies in each recruited patient. The results offer amazing hope that the invisible, devastating symptoms of fibromyalgia will become treatable."

(Excerpt) Read more at sciencedaily.com ...


TOPICS: Health/Medicine
KEYWORDS: fibromyalgia
This is kind of a big deal. It’s always been an auto-immune disorder.

Tamp down immune over reactions with less Omega-6 fats, more Omega-3 fats, Vitamin D, and antioxidants.

1 posted on 07/02/2021 10:29:10 AM PDT by ConservativeMind
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To: ConservativeMind

The drugs they give to calm down I mine systems though are really rugged drugs that create problems their own. Most will endure them ok, but some, especially those who are weak and sick in the first place, could have a harder time with the drugs. BUT it’s worth a try to see if the drugs can be tolerated


2 posted on 07/02/2021 10:36:57 AM PDT by Bob434
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To: ConservativeMind

DUH!


3 posted on 07/02/2021 10:39:25 AM PDT by SubMareener (Save us from Quarterly Freepathons! Become a MONTHLY DONOR)
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To: ConservativeMind

Fibromyalgia is from chronic magnesium deficiency


4 posted on 07/02/2021 10:52:29 AM PDT by spacejunkie2001
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To: ConservativeMind

One more reason why I love FR. People posting news like this.

My wife has fibro and now we have hope.


5 posted on 07/02/2021 11:16:11 AM PDT by Trumpisourlastchance
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To: ConservativeMind

About 20 years ago, I was suffering from debilitating back pain that led me to believe that I would never walk again very shortly. That and chronic bronchitis had plagued me all my life. Either one condition or the other had compromised me.

Then one day, I saw an article proclaiming that Guaifenesin was a cure for Fibromyalgia (FMS), and the pioneer in this discovery Dr. Raymond Paul St. Amand, was going to present a free presentation on his (guaifenesin) protocol in a Waikiki hotel. I was not familiar with FMS but was intimately familiar with guaifenesin because that’s what I took for chronic bronchitis — with the caveat not to overconsume it as the bottles warned.

Most of the people attending the presentation seemed to be FMS patients familiar with the doctor’s guaifenesin protocol — to which I noted that despite their reporting crippling pain, they actually seemed younger and healthier than the average population for their ages. That convinced me of something.

But even before hearing the presentation, I went out and got myself a few bottles of guaifenesin (cough syrup), so by the time the presentation came around, I reported that I suspected that guaifenesin cured not only FMS — but all the autoimmune conditions, as well as all illnesses — because the one characteristic effect — is to thin the mucus in the body, which most people are familiar with from taking it when they have a respiratory congestion due to the thickening of the mucus in the lungs.

However, it is logical to believe that guaifenesin has that effect not only for the mucus in the respiratory tract — but throughout the body, and thinning it as much as possible, has a favorable health effect no matter what the diagnosis. But my main takeaway from that presentation, was that despite the dire warning, guaifenesin could be taken in liberal quantities indefinitely — with beneficial effects for anybody suffering from any condition thickening the mucus — which are white blood cells attacking pathogens.

But Dr. St. Amand and associates, were adamant that they had the cure for FMS only, and to cure any other autoimmune condition, one had to see that specific specialist — and they might have a cure specifically for that disease.

So it is a lot like the thinking that requires a specific cure or vaccination for each thing that could go wrong in a body rather than a much more enlightened and less profitable model of treating each symptom as a universe all its own, rather than the belief that whatever improves the general health (immunity) of the body, is protective even against the latest unknown disease the specialists can claim as uniquely their own turf and expertise.


6 posted on 07/02/2021 11:16:47 AM PDT by MikeHu
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To: ConservativeMind

What food sources would you recommend?


7 posted on 07/02/2021 11:16:59 AM PDT by Trumpisourlastchance
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To: ConservativeMind

It’s a “disease” of psycho western women. It’s now small coincidence that Lyrica is one of the main drugs used to treat it. That’s also a drug used for anxiety.


8 posted on 07/02/2021 11:17:09 AM PDT by DesertRhino (A coup government may not claim the protection of the same constitution it overthrew. )
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To: spacejunkie2001

Took a calcium, magnesium and zinc supplement with Vit D. It was better than all the drugs I took. Even now, my transplant doctor said it was a good choice.


9 posted on 07/02/2021 11:29:38 AM PDT by KYGrandma
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To: KYGrandma

all the minerals are so critical to our health but do keep in mind that mag is the ‘mother’ of all. It makes 350 other nutrients and processes sync and absorb. So, take extra mag, especially if you’re supplementing with calcium. Take only the forms of glycinate or malate (there’s a couple more that are absorbable like taurate and orotate) but avoid oxide and probably citrate.

You should take 600-800mg/day, split throughout the day


10 posted on 07/02/2021 11:47:23 AM PDT by spacejunkie2001
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To: ConservativeMind; Trumpisourlastchance

many consider fibromyalgia to be a SYMPTOM of some other underlying disorder, usually an autoimmune disorder, and often a treatable disorder that isn’t being treated or is undertreated, such an hypothyroidism from Hashimoto’s Thyroiditis ...

btw, it’s difficult to get enough magnesium in your diet ... mag supplement should be magnesium compound that is fully reacted chelated with an amino acid because they’ll absorb better and not cause diarrhea, which actually causes even more mag to be lost (many laxatives are nothing more than inorganic mag compounds) ... a good chelated mag is magnesium taurate because taurine is good for the heart ... cheap mag compounds actually cause ... another thing is if someone really is seriously deficient in mag, it’s very difficult to build up mag levels even with supplements, and knowledgeable docs will actually start the buildup with IV mag ...


11 posted on 07/02/2021 11:47:37 AM PDT by catnipman (Cat Nipman: Vote Republican in 2012 and only be called racist one more time!)
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To: Trumpisourlastchance

If you want to follow a more formal diet that attempts to minimize autoimmune issues, there is one from a Paleo perspective, and others from a vegan perspective. Information on the Paleo one is here:

https://draxe.com/nutrition/aip-diet/
https://drjockers.com/autoimmune-diet/

However, if one knows they are truly not allergic to certain foods other might be, the approach is simpler. Simple sugars and Omega-6 fats are pro-inflammatory. Don’t use them, and stay away from breads and pasta, too. Increase your intake of high antioxidant foods. Look into supplements to further tweak your body’s immune system.

A few links:
https://www.livestrong.com/article/263431-the-best-vitamins-for-autoimmune-problems/
https://www.liverdoctor.com/the-importance-of-glutathione-for-autoimmune-disease/

Hope these help direct you and your wife!


12 posted on 07/02/2021 12:06:37 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: catnipman

Cheap magnesium oxide and citrate cause bowel issues!


13 posted on 07/02/2021 12:08:20 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: spacejunkie2001; KYGrandma

The Upper Tolerable Limit is now 350 mg of magnesium from supplements-unlimited from foods.

Too much magnesium can cause multiple issues.


14 posted on 07/02/2021 12:12:15 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

no. you should take a highly absorbable form up to bowel tolerance which is in the 600-1000mg/range. You’ll have no issues (only benefits) up to right beore loose bowels


15 posted on 07/02/2021 12:15:27 PM PDT by spacejunkie2001
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To: spacejunkie2001

600-800? You sure?


16 posted on 07/02/2021 2:23:43 PM PDT by Mount Athos
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