The Multibillion-Dollar Question: How Long Do COVID Vaccines Provide Protection?

Motley Fool ^ | 03/21/2021 | Keith Speights

[SeekAndFind]

Americans have received more than 120 million COVID-19 vaccine doses. Another 2.4 million shots are administered each day. Within the next few months, every adult in the U.S. who wants to be vaccinated will be.

But there's a big unanswered question that affects anyone who receives a COVID-19 vaccine: How long will the vaccines provide protection against novel coronavirus infection? This isn't like the old TV game show The $64,000 Question, though. How long COVID-19 vaccines last is a multibillion-dollar question.

Billions of dollars on the line

Pfizer (NYSE: PFE) and BioNTech (NASDAQ: BNTX) were the first to win U.S. Emergency Use Authorization (EUA) for their COVID-19 vaccine, BNT162b2. In February, Pfizer estimated that the vaccine would generate sales of around $15 billion this year based on supply deals in place at that time.

However, since then the two companies have received additional orders for BNT162b2 -- 100 million more doses for the U.S. and 200 million additional doses for the European Union. These deals should boost BNT162b2 sales above $20 billion in 2021.

Moderna (NASDAQ: MRNA) won EUA for its COVID-19 vaccine, mRNA-1273, soon after Pfizer and BioNTech. The biotech expects to generate $18.4 billion in sales this year from the vaccine.

Johnson & Johnson (NYSE: JNJ) secured EUA for its single-dose COVID-19 vaccine in late February. The healthcare giant is selling the vaccine at cost during the pandemic for around $10 per dose. J&J hopes to supply at least 1 billion doses of its vaccine this year. Assuming it achieves that goal, the company will make roughly $10 billion in sales.

These three vaccines alone could together make well over $48 billion this year. And we haven't included the sales for COVID-19 vaccines from AstraZeneca (NASDAQ: AZN) and Novavax (NASDAQ: NVAX), both of which could win U.S. EUA

[LibertyOh]

2012 article. Involved mice and vaccine, but not mRNA nor Covid 19. Appears mice were “sacrificed” at certain time period to study lungs etc....

[JimRed]

And how long does the infected/recovered immunity last? I’m going to get the test for antibodies (we had it in November) and I’ll pass on the results.

[ransomnote]

We know the vaccines don’t do what they want them to do and it is still highly experimental. The question for me is Does Natural Immunity that about 30% of the population enjoys, last Forever?? I think it does, mainly because when my daughter gave it to me, I barely got a head cold out of it, very mild to almost no symptoms, but I gave it to my wife who got real sick. My body already knew the formula when I got the virus, and it will remember the formula until I die. I would assume my Wife and daughter.... would all have immunity now also, and it will be forever???

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Not a doctor so I'll offer my layman's opinion here based on Vanden Bossche's video, which I'll link below.

After childhood, we function on an immune system based on 'memory' (your body has seen it before). So you have a library of pathogen 'references' your body remembers and attacks.

I think an otherwise immune person could be re-infected by something like the flu if their immune system was compromised (ill with cancer, chemo or other).

A COMING COVID CATASTROPHE [PDF and 1-hour video interview with Geert Vanden Bossche]

3/16/2021, 1:05:54 PM · by ransomnote · 70 replies

rumble.com ^ | March 11, 2021 | Geert Vanden Bossche

[Myrddin]

It has already been noted that the "vaccine" does not prevent infection nor transmission. It mitigates symptom severity. The spike protein is continuing to mutate. In the case of the D614 mutation, the virus infectivity and fatality rates increased. With millions of "vaccinated" incubators wandering the streets, there will be ample opportunity for a mutation that isn't halted by the "vaccine" to "marinate" and produce a mutant that resumes spreading.

[petitfour]

Just look at the chicken pox vaccine. It doesn’t last long. And you have to get a flu vaccine every year based on a guess, and it may or may not work though they say it works if you don’t die or get very ill. If you die, then it was because you were going to die anyway.

[eyeamok]

Interesting! I didn’t know that distributing a vaccine during a pandemic was a no no, but it does make sense. And I knew the answer to my question on immunity a long time age. I find it very frustrating as to how few people actually understand anything anymore and just follow along like sheep, parroting everything the ruling class tells them.

[ransomnote]

Interesting! I didn’t know that distributing a vaccine during a pandemic was a no no, but it does make sense. And I knew the answer to my question on immunity a long time age. I find it very frustrating as to how few people actually understand anything anymore and just follow along like sheep, parroting everything the ruling class tells them.

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Agreed.
Your question has me thinking that part of the reason they are rushing vaccination is that they don’t want people like you will to experience immunity and decline the vaccine as unnecessary.

[IamConservative]

Thank you much for the link about mutations. It was a difficult read, but very informative. Not the best news..

[Myrddin]

We're all continuously learning new data as this pandemic proceeds. I'm firmly in the camp of "engineered bioweapon" when it comes to this virus. The bioweapon engineers had their hands on this all the way. That it was released from a Chinese lab by accident or on purpose is the unanswered question. Either way, the horse is out of the barn. It's a harsh reminder that bioweapons are a really bad idea.

[ransomnote]

The unintended alternatives include the “toll like” response where spike protein expressed on a host cell is treated as “self” by the immune system and no defense is mounted.
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Re bacterial infections, if the body cannot mount a defense, drugs (antibacterial etc.) do not work because, according to the episode of HOUSE I watched, drugs only work WITH an immune response. Is this true for the “toll like” response in viral infections?

[Jim Noble]

Do they provide any protection at all?

I don't know how to post screenshots, but if you are interested, go HERE and plot the UK vs. France, or vs. Ireland, or vs. the EU, using the "per million population" if you want to compare a high-vaccination country vs. ethnically and geographically similar low-vaccination countries.

Or, you could just take my answer to your question, which is, "yes".

Probably better for you to look at the data for yourself.

[House Atreides]

“...The bad news is the “vaccinated” will be generating old spike proteins for a very long time. The mRNA is designed to be persistent.”
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Really? Do you have a link to support for that? Everything I’ve read has said the vaccines’ mRNA is relatively fragile and is degraded after about 72 hours.

https://www.nfid.org/infectious-diseases/frequently-asked-questions-about-covid-19-vaccines/

[Winniesboy]

It will last as long as they make a profit.

Worth noting that Astra Zeneca are producing their vaccine on an at-cost basis, and have said they will continue to do so until the pandemic is declared over. This, coupled with the fact that it can be transported and stored at normal temperatures, rather than the extremes required by Pfizer etc, means that outside the US the AZ is selling at about $3 a shot, compared with eg Moderna $35.