Posted on 01/15/2018 6:21:35 PM PST by nickcarraway
A provocative new study suggests that medieval plagues spread via fleas and lice on people.
Rats have long been blamed for spreading the parasites that transmitted plague throughout medieval Europe and Asia, killing millions of people. Now, a provocative new study has modeled these long-ago outbreaks and suggests that the maligned rodents may not be the culprits after all.
The study, published on Monday in the journal PNAS, instead points the finger at human parasitessuch as fleas and body licefor primarily spreading plague bacteria during the Second Pandemic, a series of devastating outbreaks that spanned from the 1300s to the early 1800s.
These outbreaks include the infamous Black Death, which wiped out a third of Europes population in the mid-1300s, amassing a body count in the tens of millions.
The plague really transformed human history, so its really important to understand how it was spreading and why it was spreading so fast, says lead study author Katharine Dean, a doctoral research fellow at the University of Oslos Centre for Ecological and Evolutionary Synthesis.
DEADLY BITE
When fleas infected with the bacterium Yersinia pestis bite humans, the bacteria can jump into the bloodstream and congregate in humans lymph nodes, which are found throughout the body. The infection causes lymph nodes to swell into ghastly buboes, the namesakes for bubonic plague. (Find out how plague bacteria evolved.)
In cases of plague since the late 1800sincluding an outbreak in Madagascar in 2017rats and other rodents helped spread the disease. If Y. pestis infects rats, the bacterium can pass to fleas that drink the rodents blood. When a plague-stricken rat dies, its parasites abandon the corpse and may go on to bite humans.
Because of rats role in modern plagues, as well as genetic evidence that medieval plague victims died of Y. pestis, many experts think that rats also spread plague during the Second Pandemic.
In 1986, archaeologists uncovered a mass grave in East Smithfield, London, used to bury victims of the Black Death in the 1340s. At the time, one observer said that 200 victims of the plague were being buried each day. PHOTOGRAPH BY MOLA/GETTY But some historians argue that the Black Death may have spread differently. For one, the Black Death tore through Europe far faster than any modern plague outbreaks. In addition, rat falls precede some modern outbreaks, but medieval plague records dont mention rats dying en masse.
Geneticists and modern historians were putting the rat into the position [of spreading the plague] and were straining bits of evidence, says Samuel Cohn, a University of Glasgow medieval historian who has criticized the rat-flea theory.
As an alternative, some scholars have long toyed with the idea that fleas on humans spread the Black Death. If fleas and lice picked up the plague by biting an infected human, they could potentially hop onto a person in close quarters and transmit the disease.
Mathematically, the patterns in how disease moves through a population are different for the rat-flea and human-parasite modes of transmission. To put them to the test, Deans team modeled each with equations that simulated the rise and fall of an outbreak, based on how rats, fleas, and body lice would behave and spread plague.
Its basically bookkeepingyou see how people move [in the simulation], says coauthor Boris Valentijn Schmid, a University of Oslo computational biologist and Deans Ph.D. adviser.
After running their models many times, Dean and Schmid statistically evaluated which models best matched mortality patterns from nine different European plague outbreaks from the Second Pandemic. To their surprise, they found that in seven of the nine cities they examined, the human-parasite model more closely fit mortality records than the rat-flea model.
Its a really cool piece of work, says Charles Chick Macal, a systems scientist at Argonne National Laboratory who models the spread of diseases but wasnt involved with this study. It gets at the underlying question of why these outbreaks occur at all.
Dean and Schmid say that theres room to improve their models with more experimental data. They also acknowledge that their study is likely going to stir controversy among plague scholars, some of whom passionately argue that rats caused the medieval outbreaks.
In plague, theres a lot of hot debate, says Dean, who sees herself and Schmid as more objective observers in this case. We have no dogs in this fight.
That's what I've always heard. The rats were the carriers.
Whooooaaa
Getting a plague shot in ‘73 was a real icky feeling
Like- wth is THIS about
Thanks for being unwilling guinea pigs to improve the safety of the vaccine!
Spread by seamen.
Anything warm blooded can carry the fleas.
Oops. I'm glad you lived through it.
Bacteria and viruses are always trying to get around whatever barriers we try to erect.
I thought so, too.
See my post #27.
Plague Infected Humans Much Earlier Than Previously Thought [2794 BC]
EurekAlert! | October 22, 2015 | Joseph Caputo of Cell Press
Posted on 10/24/2015 6:14:01 PM PDT by SunkenCiv
http://www.freerepublic.com/focus/f-chat/3352556/posts
Thanks nickcarraway.
More revisionist blather ...
The rats have hired a P.R. team to scrub their past and finger the insects.
Figures.
Rats.
The term “Black Death” was not used during the Middle Ages but was coined later. The same goes for “Renaissance,” “Industrial Revolution” and “Roaring Twenties,” labels which were coined long after the periods to which they refer.
I recall that in London at the time they thought that dogs were the cause of the plague and set out to exterminate dogs.
Of course, with no dogs to kill rats the rat population exploded.
And this is new News ???? How stupid, learned this as a child ....
A few years ago I read that some researchers felt that bubonic plague could not be the Black Death, or at least not the only cause. I believe the lack of rats in done areas was part of it but also how the plague progressed in its victims. Maybe those theories have been discounted since that time.
If I recall correctly, the article I read indicated that anthrax and an Ebola like virus were thought to be possibilities. I think they excavated an old human burial ground in London of the time and they found anthrax. Again if I remember right cattle was kept in that area back at the time of the Black Death.
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