Posted on 04/17/2017 9:33:52 AM PDT by Ernest_at_the_Beach
Tensions are escalating in the long-running dispute between two major groups over the research and rights to Crispr, a biological system that has been adapted to easily edit the genes of animals, plants and people.
(Excerpt) Read more at wsj.com ...
fyi
WSJ is late getting to this, they don’t have any exclusive hold over the tech.
Here is a nice lead up to the tech:
https://www.nature.com/polopoly_fs/1.19510!/menu/main/topColumns/topLeftColumn/pdf/531156a.pdf
here’s some of it...
“are escalating in the long-running dispute between two major groups over the research and rights to Crispr, a biological system that has been adapted to easily edit the genes of animals, plants and people.
A group including University of California, the University of Vienna and researcher Emmanuelle Charpentier said on Wednesday that it seeks to overturn a patent decision related to the best-known Crispr system, Crispr-cas9.
That decision by the Patent Trial and Appeal Board protected Crispr-cas9 patents issued to the Broad Institute, Harvard University and the Massachusetts Institute of Technology against a challenge by the California group.
Separately, scientists from the Broad, MIT and Harvard reported in the journal Science on Thursday that they adapted a different Crispr system, Crispr-cas13a, to create a diagnostic tool that can detect a range of viruses, bacteria and other medical information.
Some of the same scientists involved in the Crispr-cas9 dispute are also inventors of Crispr-cas13a diagnostic tools and have filed for patents on that use as well. The two systems use different enzymes.
The events of this week highlight the tensions that can emerge when trying to determine where transformative ideas come from in science, particularly when scientific prestige or potential financial rewards are also at stake.
The Broad group in announcing its new diagnostics system specifically noted the work of Jennifer Doudna, a professor at UC Berkeley who has done research in both systems, saying the Broads cas13a work is a million-fold more sensitive than Dr. Doudnas.
Dr. Doudna in emails said the new tool combines two previously reported methods, one by her group, and improves the ability of detection but “could be challenging to scale commercially.
In the case of Crispr-cas9, hundreds of millions of dollars of investment have flowed into startups seeking to use the gene-editing system to develop therapeutics and cures for disease. As the patent dispute drags on, it is unclear whether the companies will have to license the technology from both sides.......”
I’m confused. There’s a shock :)
If you get a genetic disease, which could be diabetes, cancer, heck schizophrenia, can gene therapy help you once you have the disease or is it only useful if the gene runs in your family and they modify the gene before you get said disease later on in life.
I guess in other words, could it treat people BORN with a disease or is it too late at that point.
You can have a genetic disposition to diabetes but not get it until 40. If it can be corrected at a young age, you don’t have to worry.
:)
I’m with ya - I only PLAY a doctor on FR....
waiting for an explanation myself...
Google search : CRISPR/Cas9 Services
Yes, it does have the potential to edit genes of living organisms. Much work remains to be done before we have treatments for specific genetic problems though because this technology, however promising, is still in its infancy.
This is shaping up to be the patent battle of the century like Wright/Curtis 100 years ago.
Some people believe the impact could be similar to that of aviation...
Other real medical practitioners will need to see if the stuff does any good.
Amazing that seawater mud puddles evolved into such a mind-bogglingly complex biological programming system, hey?
Maybe we should grind up some silicon and such and throw it into a seawater mud puddle, bombard the mud puddle with a Tesla Coil and see what kind of computer will eventually emerge.
Disease-resistant pigs latest win for gene editing technology
Posted by o_1_2_3__.
Gotcha, now I have to look up WRight/Curtis and i don’t know what you’re referring to when you say regarding aviation.
One learns so much on this board :)
Throw in an old Smith-Corona. Maybe the next Great American Novel will come out: a two-fer.
How much grant money did the US govt pay to either side and does the US get to receive appropriate licensing fees as a result?
Ha! Well, some sort of computing entity might emerge but not a conscious aware spirit. There’s a difference.
Sir Roger Penrose here:
https://www.youtube.com/watch?v=3WXTX0IUaOg
It’s a reference to the patent war between Wright Bros. and Glenn Curtiss over approaches to control aircraft.
The battle dragged out for a long time hurting both groups. They finally merged...
Thanks
for later
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