In preliminary trials, involving 165 people in the early stages of the disease, the Swiss-designed drug triggered the removal of amyloid from the brain.
And in men and women given a monthly infusion of a high dose of the drug, the amyloid all but vanished after a year.
This ‘unprecedented’ effect was deemed so significant that the results have been published in Nature the world’s top science journal.
Other amyloid-busting antibodies have been tried before.
But aducanumab, which is based on antibodies naturally made by pensioners who seem to be immune to Alzheimer’s, is said to be the best yet.
It is thought it is better at getting into the brain and more likely to zero in on the damaging amyloid than previous drugs. (more information at news source)
Is this truly for real?
"Swiss-designed drug triggered the removal of amyloid from the brain "
We can but hope.
A disease of near unparalleled evil.
So many Alzheimer’s related jobs will be lost.
Good!!
Because many of the 300k soldiers with brain injuries are more likely to develop alzheimer’s.
I could probably use a batch in several years too!!!
I need this!
Need what?
I’ll read it later and find out. : [
Make that healthy, WEALTHY, pensioners. On our side of the pond, those not on Obamacare.
I watched the same video, where she almost fell out of her van, only to be caught by a secret service guy. And she expects to be president?
Oh, wait a minute, am I on the right thread?
Go Big Pharma !
Excitng news! Thanks you.
If this is true, one of the next big (and I mean BIG) issues in this country will be the great demand for the drug vs. the long FDA approval journey most drugs have to go thru before they are allowed to be prescribed.
Given the great damage that victims of this disease (and their families) suffer I can foresee literally (and I’m using that word correctly) riots in the streets over this.
I hope it’s true and I wish I could get my mom into a trial but they are in England.
Next up, make the world a much better place and finally cure the most cruel mental disorder of all: liberalism.
Aducanumab
Sounds more like a test for Alzheimer’s. If you can pronounce this, and remember it 5 minutes later, you don’t need it.
Might be better backwards though. Bamunacuda has a better flow to it.
https://clinicaltrials.gov/ct2/results?term=aducanumab&Search=Search
There are lots (~175) of study locations
Ages Eligible for Study: 50 Years to 85 Years (Adult, Senior)
Genders Eligible for Study: Both
Accepts Healthy Volunteers: No
Criteria
Key Inclusion Criteria:
•Must meet all of the following clinical criteria for MCI due to AD or mild AD and must have:
•A Clinical Dementia Rating (CDR)-Global Score of 0.5.
•Objective evidence of cognitive impairment at screening
•An MMSE score between 24 and 30 (inclusive)
•Must have a positive amyloid Positron Emission Tomography (PET) scan
•Must consent to apolipoprotein E (ApoE) genotyping
•If using drugs to treat symptoms related to AD, doses must be stable for at least 8 weeks prior to screening visit 1
•Must have a reliable informant or caregiver
Key Exclusion Criteria:
•Any medical or neurological condition (other than Alzheimer’s Disease) that might be a contributing cause of the subject’s cognitive impairment
•Have had a stroke or Transient Ischemic Attack (TIA) or unexplained loss of consciousness in the past 1 year
•Clinically significant psychiatric illness in past 6 months
•History of unstable angina, myocardial infarction, advanced chronic heart failure, or clinically significant conduction abnormalities within 1 year prior to Screening
•Indication of impaired renal or liver function
•Have human immunodeficiency virus (HIV) infection
•Have a significant systematic illness or infection in past 30 days
•Relevant brain hemorrhage, bleeding disorder and cerebrovascular abnormalities
•Any contraindications to brain magnetic resonance imaging (MRI) or PET scans
•Alcohol or substance abuse in past 1 year
•Taking blood thinners (except for aspirin at a prophylactic dose or less)
https://clinicaltrials.gov/ct2/show/NCT02477800?term=aducanumab&rank=5
If it fixes brain damage, it could be the cure for democrats and rino’s alike!!!
Recently on www.PeoplesPharmacy.com was a program that explained how to detect Alz early and before symptoms, by looking at the retina in the eye.
The good part is then they can reverse it. It had to do with DIET !
an older article from 2015, before the additional testing:
http://www.dddmag.com/article/2015/04/story-biogens-alzheimers-drug-aducanumab