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Exenatide (Byetta) Has Rapid, Powerful Anti-inflammatory Effect, UB Study Shows
The University at Buffalo ^ | November 2, 2011

Posted on 11/02/2011 8:19:57 AM PDT by decimon

BUFFALO, N.Y. -- Exenatide, a drug commonly prescribed to help patients with type 2 diabetes improve blood sugar control, also has a powerful and rapid anti-inflammatory effect, a University at Buffalo study has shown.

The study of the drug, marketed under the trade name Byetta, was published recently in the Journal of Clinical Endocrinology and Metabolism.

"Our most important finding was this rapid, anti-inflammatory effect, which may lead to the inhibition of atherosclerosis, the major cause of heart attacks, strokes and gangrene in diabetics," says Paresh Dandona, MD, UB Distinguished Professor in the Department of Medicine, UB School of Medicine and Biomedical Sciences, and senior author.

It was especially noteworthy that this anti-inflammatory effect occurred independently of weight loss over the 12-week study period, he adds.

(Excerpt) Read more at buffalo.edu ...


TOPICS: Health/Medicine; Science
KEYWORDS: byetta; exenatide; inflammation; type2diabetes

1 posted on 11/02/2011 8:19:59 AM PDT by decimon
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To: neverdem; DvdMom; grey_whiskers; Ladysmith; Roos_Girl; Silentgypsy; conservative cat; ...

Ping


2 posted on 11/02/2011 8:20:39 AM PDT by decimon
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To: decimon

Not necessarily surprising since there is some growing evidence that type 2 is an autoimmmune reaction of some type. Inflamation is an immune reaction and there might be a solid link. Interesting article. Injecting it twice a day? No, I’ll stick to diet, exercise and metformin to keep my blood sugar under control and an aspirin a day to help keep down the inflamation and plaque.


3 posted on 11/02/2011 8:57:07 AM PDT by RJS1950 (The democrats are the "enemies foreign and domestic" cited in the federal oath)
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To: RJS1950

You might find a new book titled “Wheat Belly” of interest. It is written by a cardiologist, and well worth the read!

Eliminating wheat in all it’s forms can help with Diabetes.


4 posted on 11/02/2011 9:02:59 AM PDT by jacquej
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To: expat1000

bflr


5 posted on 11/02/2011 9:19:26 AM PDT by expat1000
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To: jacquej

A low carb diet does much the same and I tried it for a couple of years; worked pretty well. Now I keep the wheat/gluten/carbs down but I don’t entirely eliminate them.


6 posted on 11/02/2011 10:11:27 AM PDT by RJS1950 (The democrats are the "enemies foreign and domestic" cited in the federal oath)
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To: RJS1950

Here is the Wheat Belly book, on Amazon. I think there is enough information on the page for you to get a feel for the book. It isn’t really a diet book.

There is a lot of information on how wheat has been genetically modified in the past 40 or 50 years, and why the changes have had such a disastrous impact on our health.

http://www.amazon.com/Wheat-Belly-Lose-Weight-Health/dp/1609611543


7 posted on 11/02/2011 10:33:57 AM PDT by jacquej
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To: decimon

Number one reason most folks quit taking it is nausea.


8 posted on 11/02/2011 3:55:16 PM PDT by TASMANIANRED (We kneel to no prince but the Prince of Peace)
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To: decimon
You're welcome.


9 posted on 11/02/2011 4:07:21 PM PDT by Wallop the Cat
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To: RJS1950; decimon; austinmark; FreedomCalls; IslandJeff; JRochelle; MarMema; Txsleuth; Newtoidaho; ..
Drug Derived From Gila Monster Saliva Helps Diabetics Control Glucose, Lose Weight Exenatide

Exenatide Exerts a Potent Antiinflammatory Effect

There are a bunch of actors from the innate immune system mentioned in the abstract at the 2nd link.

FReepmail me if you want on or off the diabetes and/or ping lists.

P.S. ScienceDaily often carries identical press releases. If the results of a new study are not announced at a conference, but are in a new article, then ScienceDaily often links it. I searched Exenatide Byetta in Yahoo News. I saw the 2nd link almost instantly.

10 posted on 11/02/2011 7:49:30 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem
ScienceDaily often carries identical press releases.

A bunch of sites do. I got to this through EurekAlert and usually go there out of habit.

11 posted on 11/02/2011 7:57:09 PM PDT by decimon
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To: Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; Battle Axe; null and void; ...

Check the 2nd link in comment# 10. I forgot to include you.


12 posted on 11/02/2011 8:22:57 PM PDT by neverdem (Xin loi minh oi)
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To: TASMANIANRED; decimon
That's why they took me off Byetta. I mentioned nausea and they put an end to it. Byetta was still new enough that drs. took extra precautions.

Recently I asked about taking it again and they suggested that smaller doses might be just as effective.

13 posted on 11/02/2011 8:41:46 PM PDT by Lady Jag (Notice how the Democrat party is all Democratic now)
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

Ping! (Thanks, neverdem!)


14 posted on 11/02/2011 11:00:27 PM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: decimon

I tried Byetta when it first came out. Didn’t do much for me.


15 posted on 11/03/2011 7:06:23 AM PDT by A. Patriot (Have we lost our Republic? Do the majority of Americans care?)
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To: Smokin' Joe

Thanks for the ping!


16 posted on 11/03/2011 1:26:24 PM PDT by Alamo-Girl
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To: Alamo-Girl

You’re Welcome, Alamo-Girl!


17 posted on 11/03/2011 1:39:59 PM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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