Free Republic
Browse · Search
News/Activism
Topics · Post Article

Skip to comments.

An ingredient in olive oil that appears to kill cancer cells
Kurzweil ^ | 2-20-15 | Unknown

Posted on 02/21/2015 11:40:43 AM PST by Tired of Taxes

A Rutgers nutritional scientist and two cancer biologists at New York City’s Hunter College have found that an ingredient in extra-virgin olive oil kills a variety of human cancer cells without harming healthy cells.

The ingredient is oleocanthal, a compound that ruptures a part of the cancerous cell, releasing enzymes that cause cell death.

Paul Breslin, professor of nutritional sciences in the School of Environmental and Biological Sciences, and David Foster and Onica LeGendre of Hunter College, report that oleocanthal kills cancerous cells in the laboratory by rupturing vesicles that store the cell’s waste.

The findings are published in Molecular and Cellular Oncology.

Scientists knew that oleocanthal killed some cancer cells, but no one really understood how this occurred. Breslin believed that oleocanthal might be targeting a key protein in cancer cells that triggers a programmed cell death, known as apoptosis, and worked with Foster and Legendre to test his hypothesis.

“We needed to determine if oleocanthal was targeting that protein and causing the cells to die,” Breslin said.

After applying oleocanthal to the cancer cells, Foster and LeGendre discovered that the cancer cells were dying very quickly — within 30 minutes to an hour. Since programmed cell death takes between 16 and 24 hours, the scientists realized that something else had to be causing the cancer cells to break down and die.

Pancreatic cancer (PC3) cells treated with an increasing dose of olive-oil ingredent (-)-Oleocanthal (OC) in the absence of serum (fetal bovine serum). After 30 minutes of treatment, 100% of cells have been detached from the plate. Survival and growth of PC3 cells depend on being attached, so loss of attachment and the rapid rounding of cells seen in 20 micromolar (20µM) concentration of OC indicate these cancer cells are dead. (credit: Dr. Onica LeGendre)

LeGendre, a chemist, provided the answer: The cancer cells were being killed by their own enzymes. The oleocanthal was puncturing the vesicles inside the cancer cells that store the cell’s waste. These vesicles, known as lysosomes are larger in cancer cells than in healthy cells, and they contain a lot of waste. “Once you open one of those things, all hell breaks loose,” Breslin said.

But oleocanthal didn’t harm healthy cells, the researchers found. It merely stopped their life cycles temporarily — “put them to sleep,” Breslin said. After a day, the healthy cells resumed their cycles.

The researchers say the logical next step is to go beyond laboratory conditions and show that oleocanthal can kill cancer cells and shrink tumors in living animals. “We also need to understand why it is that cancerous cells are more sensitive to oleocanthal than non-cancerous cells,” Foster said.

It will also be interesting to explore the implications of this study for research suggesting beneficial effects of ingesting fullerenes dissolved in olive oil.

According to the World Health Organization’s World Cancer Report 2014, there were more than 14 million new cases of cancer in 2012 and more than 8 million deaths.


TOPICS: Culture/Society
KEYWORDS: agriculture; animalhusbandry; cancer; cancercure; evoo; health; helixmakemineadouble; huntercollege; huntergatherers; newyorkcity; oliveoil
Navigation: use the links below to view more comments.
first previous 1-2021-4041-6061-77 next last
To: BykrBayb
There are a host of health benefits to consuming olive oil.

If you don't cook like I don't, can you still take maybe a teaspoon of extra virgin olive oil a day?

21 posted on 02/21/2015 12:32:08 PM PST by Hot Tabasco (Uncle Sy: "Beavers are like Ninjas, they only come out at night and they're hard to find")
[ Post Reply | Private Reply | To 12 | View Replies]

To: Tired of Taxes
The ingredient is oleocanthal, a compound that ruptures a part of the cancerous cell, releasing enzymes that cause cell death.

Countdown: 5-4-3-2-1......

GET YOUR BOTTTLE OF OLEOCANTHAL TODAY! Only $29.99 that's $29.99....Get prepared to hear commercials about this 9 GABILLION times a day!

22 posted on 02/21/2015 12:39:24 PM PST by GrandJediMasterYoda (Obama: 12 acts of blatant treason and counting)
[ Post Reply | Private Reply | To 1 | View Replies]

To: MAINE-IAC; All

Indeed, there’s an additional chart on the site I mentioned in my post # 18, re rate of cancer in countries, that lists the top 59 countries - and GREECE isn’t even among them - GREECE is one of the top, if not the top, countries who are famous for their Mediterranean Diet

Italy is #18 - but they consume a lot of OO that is heated in the process of cooking -

Indeed, the scientists may be onto something - also, tho’ read my post #18 re the WAYS to consume OO

http://www.theguardian.com/news/datablog/2011/jan/24/worldwide-cancer-rates-uk-rate-drops


23 posted on 02/21/2015 12:39:25 PM PST by maine-iac7 (Christian is as Christian does - by their fruits ye shall know them.)
[ Post Reply | Private Reply | To 18 | View Replies]

To: Tired of Taxes

THIS is why I must relocate to the Adriatic Sea area. A small island off of Croatia among the olive trees and grape vines is where I belong. Under the beating sun and seashell beaches...dousing my fresh caught fish in olive oil and washing it down with homemade wine.


24 posted on 02/21/2015 12:40:00 PM PST by riri (Obama's Amerika--Not a fun place.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: southern rock
Olive Oil is 100% FAT. Cure your cancer. Die of heart disease.

You are falling for the big government "food pyramid" narrative. The same government that caterwauls about "global warming" while the Great Lakes freeze and New England is buried under 7 feet of snow.

Olive oil is a superfood and one of the healthiest substances you can put in your body.

By the way, so are eggs, which the government has been saying for years is bad for us because they have "cholesterol." The government had housewives in a panic over this, buying "egg beaters" and making omelets with egg whites (sacrilege!). When in fact, eggs are one of nature's most perfect foods.

As well, the government had us all scared of butter and as a result, housewives were buying margarine, which is basically a stick of chemicals and laden with hydrogenated oils which are toxic to our bodies. The switch to margarine from butter had devastating consequences for our health.

There are many things the government tells us that just-are-not-true.

25 posted on 02/21/2015 12:40:13 PM PST by SamAdams76
[ Post Reply | Private Reply | To 10 | View Replies]

To: Tired of Taxes

Some research shows that the low-fat diet craze may be what has lead to the explosion of Alzheimer’s.

http://www.faim.org/brainhealth/do-low-fat-diets-cause-alzheimers.html


26 posted on 02/21/2015 12:41:26 PM PST by SFmom
[ Post Reply | Private Reply | To 1 | View Replies]

To: Tired of Taxes

bookmark


27 posted on 02/21/2015 12:45:19 PM PST by dadfly
[ Post Reply | Private Reply | To 1 | View Replies]

To: BykrBayb

And the cowboys in my family use olive oil to treat their leather boots, saddles, etc. Works great and is good to eat also. We buy a lot of olive oil and nobody has cancer. That’s pretty rigorous proof it’s good for something. yup.


28 posted on 02/21/2015 1:01:47 PM PST by cherokee1 (skip the names---just kick the buttz)
[ Post Reply | Private Reply | To 12 | View Replies]

To: Hot Tabasco

>>If you don’t cook like I don’t, can you still take maybe a teaspoon of extra virgin olive oil a day?<<

The bread and salt might not be good for you, but many days I put olive oil in a small bowl, add salt and pepper, and then dip a slice of bread in it, instead of buttering the bread. It’s actually quite good and, given this report, I might even eat it more often from now on.


29 posted on 02/21/2015 1:03:51 PM PST by Norseman (Defund the Left-Completely!)
[ Post Reply | Private Reply | To 21 | View Replies]

To: 9thLife

So does a ball peen hammer,I just didn’t publish my results


30 posted on 02/21/2015 1:08:01 PM PST by Cyman (We have to pass it to see what's in it= definition of stool sample)
[ Post Reply | Private Reply | To 2 | View Replies]

To: Our man in washington
Definitely true. I’ve seen “The Godfather”. Those guys ate olive oil all the time,

I saw it too and all of them died prematurely.........Makes one go Hmmmmmmmmmmm

31 posted on 02/21/2015 1:14:58 PM PST by Hot Tabasco (Uncle Sy: "Beavers are like Ninjas, they only come out at night and they're hard to find")
[ Post Reply | Private Reply | To 13 | View Replies]

To: riri
"Under the beating sun and seashell beaches...dousing my fresh caught fish in olive oil and washing it down with homemade wine.

High Diddley-Dee, that's the life for me baby.

32 posted on 02/21/2015 1:18:21 PM PST by semaj
[ Post Reply | Private Reply | To 24 | View Replies]

To: SamAdams76; southern rock
"There are many things the government tells us that just-are-not-true. "

I concur. May I recommend a great book for anyone interested in in improving their overall health? "Grain Brain," by David Perlmutter and Kristin Loberg.

33 posted on 02/21/2015 1:22:05 PM PST by semaj
[ Post Reply | Private Reply | To 25 | View Replies]

To: Greetings_Puny_Humans

34 posted on 02/21/2015 1:24:02 PM PST by COBOL2Java ("God save America" - we are at the dawn of a new dark age)
[ Post Reply | Private Reply | To 5 | View Replies]

To: Hot Tabasco

I don’t see why not.

My favorite salad dressing is just balsamic vinaigrette and olive oil.

Bread usually tastes better with olive oil and Italian seasoning than with butter.

I enjoy the health benefits of olive oil, but that’s not the reason I use it. I just like it better than the alternatives on some things. I still use lard in my biscuits and pie crusts. I gave up potato chips for Lent and I might not survive it.


35 posted on 02/21/2015 1:27:06 PM PST by BykrBayb (Where there is life, there is hope. - Terri Schiavo ~ Þ)
[ Post Reply | Private Reply | To 21 | View Replies]

To: Tired of Taxes

Why olive oil and not olives?


36 posted on 02/21/2015 1:28:25 PM PST by AppyPappy (If you are not part of the solution, there is good money to be made prolonging the problem.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: cherokee1

Occasionally I oil my wooden cutting boards with olive oil. I drench them thoroughly, and it soaks in overnight.


37 posted on 02/21/2015 1:29:30 PM PST by BykrBayb (Where there is life, there is hope. - Terri Schiavo ~ Þ)
[ Post Reply | Private Reply | To 28 | View Replies]

To: SamAdams76
Best olive oil around.

http://seagateproducts.com/product/291/100%25-Extra-Virgin-Olive-Oil.html

38 posted on 02/21/2015 1:31:00 PM PST by petercooper ("How To Destroy The Country In 6 Short Years" by Barack Obama & the Democrats)
[ Post Reply | Private Reply | To 25 | View Replies]

To: petercooper

http://seagateproducts.com/product/291/100%25-Extra-Virgin-Olive-Oil.html


39 posted on 02/21/2015 1:31:16 PM PST by petercooper ("How To Destroy The Country In 6 Short Years" by Barack Obama & the Democrats)
[ Post Reply | Private Reply | To 38 | View Replies]

To: Tired of Taxes

The February, 2015 edition of Reader’s Digest has a story about a man living here since 1943 from Greece who develop cancer and was told he had 9 months. He was in his mid 60’s. He and his wife moved to Greece to an island called Ikaria. He ate all the local foods and drank the local wine.
He lived until 102 and past away in 2013.

He went back to America for a visit years ago to see if the doctors he had could explain it but they were all dead....

Here is a cnn story that includes him from 2009. Differs a bit from Reader’s Digest.
http://edition.cnn.com/2009/HEALTH/04/16/longevity/


40 posted on 02/21/2015 1:55:51 PM PST by minnesota_bound
[ Post Reply | Private Reply | To 1 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-4041-6061-77 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
News/Activism
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson