This should be a real free-for-all.
Posted on 09/03/2022 4:51:43 PM PDT by SunkenCiv
A group of international researchers has uncovered evidence of a super rare genetic condition that gives men an extra X chromosome, reporting the oldest clinical case of Klinefelter Syndrome to date.
The evidence comes from a 1,000-year-old skeleton from Portugal.
Klinefelter Syndrome is a rare genetic condition where individuals are born with an extra copy of the X chromosome, occurring in approximately one in 1,000 genetic-male births...
The team began by analysing genetic information obtained from a skeleton found in northeastern Portugal that had been radiocarbon dated to the 11th century by researchers from the University of Coimbra in Portugal...
The researchers say the findings will help establish a historic record for Klinefelter Syndrome, as well as enhance understanding of its prevalence throughout human history...
Given the well preserved state of the specimen, the researchers were also able to determine physical traits in the skeleton compatible with Klinefelter Syndrome...
he researchers suggest their new method to analyse this particular skeleton can be further improved to study different chromosomal abnormalities in other archaeological specimens, including Down Syndrome.
This research is published in The Lancet.
(Excerpt) Read more at anu.edu.au ...
This should be a real free-for-all.
I have a relative with that. It comes with personality traits as well as physical traits, including black-and-white thinking (no nuance or middle ground), difficulty learning. Many end up in jail. Physically, they have a certain walk and posture, little facial hair, and they are sterile. It’s a tough life sentence for little boys to grow up with.
I know someone who has this (his wife told me about it).
He was sterile and definitely a little more violent than expected, and had some psychological issues (looking back).
Very sad.
The symptoms sound like Aspergers + Fetal Alcohol Syndrome.
That would equal a very tough life, even under the best of circumstances, where they receive early treatment.
Probably caused by the vaccine... < / s >
Klinefelter’s is seen in other mammals as well, most prominently in house cats. It’s the only way you can get those 1 in 10000 births male tortoiseshell cats.
CC
Klinefelter also invented a time machine, making him at least a triple threat.
Hmm, triple threat.
Now I want ice cream...
A thousand years ago in Portugal it would seem to be an advantage. medieval times were noted for men who were short tempered, violent and thought in black and white terms. Would make for a loyal retainer or a good crusader.
That would work, up to the day where he misreads/misjudges a situation and ends up injured or dead. But then, in the Middle Ages, you needn’t have had Klinefelter’s for that to happen, anyway.
Male tortoiseshell cats can also be chimeras and not have Klinefelter's. There is a beautiful male Maine Coon bred in a Texas cattery which is a chimera. I almost bought a kitten sired by him, but then the breeder thought that the kitten was actually a torbie instead of a tortie and white, which is what I wanted, so I bought my Dandi from another breeder. Her father is also a Regional Winner from the Mid-Atlantic region.
This cat is Regional Winner (RW) SGC Dawntreader Texas Calboy. He has an interesting story.
This is an excerpt from Cat Gazette which gives a good succinct explanation of Calboy's chimera condition.
RW SGC Dawntreader Texas Calboy:
"...Calboy is unique as an extremely rare fertile male calico, since most of the males who sport the coat color are incapable of reproducing. Only one out of 10,000 male calicos are capable of fathering kittens.
So how does a coat color associated almost entirely with female cats end up on a male, and why is the combination so rare? Calboy is a chimera, according to veterinarian Brittney Barton of HEAL Veterinary Hospital in Dallas..." And what is a chimera?
According to the article in Cat Gazette, chimeras have two sets of DNA, Barton said. Normally, “we have one embryo with two different, separate, fertilization incidents,” which results in non-identical twins, the veterinarian explained. “Where a chimera comes in,” Barton said, “that’s when non-identical twins merge...Male cats have X and Y chromosomes, while female cats have two X chromosomes. The X chromosome is responsible for coat color: With only one X, males can be either orange or black, but normally not both. But with two X chromosomes, females can be orange and black. A chimera like Calboy has three chromosomes — XXY — which is caused by an incomplete division of the male’s XY chromosome pair at the time of fertilization, according to the University of Miami. The unusual combination allows a cat like Calboy to develop a coat pattern and color combination that would be normally impossible for males.”
Calboy is even more special because he is FERTILE. His breeder, thinking he was XXY and therefore sterile, let him run around her breeding girls at will. When he was 7 months old, she started noticing several of her girls were pregnant, and the only male who had access to them had been Calboy. She had him tested and...he was fertile. As I said, I almost bought a beautiful kitten sired by him.
SGC Calboy 's honors include:
2019 Best Maine Coon in TICA's South Central Region.
2019 20th Best Cat in the South Central Region
2019 6th Best Long Haired Cat
Has Earned His Championship, Grand Championship, Double Grand Championship, Triple Grand Championship, Quadruple Grand Championship and his Supreme Grand Championship along with Regional Winner During his show career.
Could he be a Viking Kitty?
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