Posted on 05/29/2003 12:27:11 AM PDT by Judith Anne
A new study, released early by the Canadian Medical Association Journal, shows that the toll SARS takes on health care workers is more profound than many doctors expected.
The research is based on 14 Toronto-area health care workers, many of them nurses, who developed SARS in late March. They suffered from fatigue, pneumonia, and in some cases severe life threatening anemia.
Of the 14 studied, 13 have still not returned to work, weeks after they were released from hospital. And many may be suffering from Post Traumatic Stress Disorder, similar to soldiers returning from war.
The study is the most detailed clinical analysis of what happens to people hit by the new and mysterious illness. It was released on the CMAJ website about a month before the paper's appearance in the print version of CMAJ.
CMAJ STUDY:Clinical course and management of SARS in health care workers in Toronto
The study found that the disease usually developed within four four days of exposure. It often caused full pneumonia in less than three days. Patients remained in hospital for a mean of 14 days.
Many suffered temporary heart problems and long term breathing problems that still persist up to eight weeks later, leaving them breathless and exhausted.
"These are healthy health care workers. The mean age was 42, so they are not old people," explains Dr. Monica Avendano, one of the authors of the study.
Another key finding from the study is the high number of patients who developed severe hemolytic anemia. Some required lifesaving blood transfusions.
The doctors aren't certain whether the anemia is a results of the SARS itself or a complication of treatment, possibly associated with the use of ribavirin, an anti-viral drug doctors were testing on patients at the time. The drug is no longer in use.
Most striking of all the effects were the deep psychological and emotional problem, including insomnia and nightmares. Most of the patients expressed feelings of fear, depression and anxiety at the time of the acute illness.
Pat Tamilin, one of those studied, was "sicker than I've ever been ... it's worse than any pneumonia." And she's concerned about going back to work. "I don't want to be the first health care worker to get SARS twice," she said.
In addition, many of those in the study expressed frustration at being in isolation and without contact with family and loved ones. This was particularly the case for those patients with young children, and especially the two patients whose children developed SARS.
"We are convinced that they have some sort of post traumatic stress disorder," says Dr. Avendano
There was one bright bit of news. The study found that the 14 subjects had contact with 33 family members. Of them, only two developed SARS, and both were mild cases. But disturbingly, one didn't develop symptoms until 12 days after the last contact with the family member -- suggesting that the 10-day quarantine period currently recommended may not be long enough.
The conclusion of the doctors is that SARS is a fast moving disease that if survived, results in a long slow recovery once the acute phase of the disease ends -- as long as two months.
Only one of the 14 subjects has returned to work. If that trend continues and more health care workers are similarly affected in this second wave of cases, it could seriously deplete the health care system.
"The disease continues to linger, the inflammatory process stays for a long time, and we don't know how long," says Dr. Peter Derkach, another of the study's authors.
That's why researchers plan to follow these health care workers for some time to come, to get the clearest picture of the long-term effects of the disease.
These nurses could be US nurses, this fall...I'm glad they aren't using ribavirin anymore, it is very toxic and doesn't help with SARS, but I wish it had been more useful against the virus...
That's something I've said for some time now... SARS victims need to remain in some type of isolation environment for a period of time after they have appeared to recover.... we know they will still be shedding the virus for weeks afterwards.
5/23/03 MMWR Weekly | Update: SARS --- United States, May 21, 2003
Updates numbers of reported cases in United States as of May 21, 2003. A total of 7,956 SARS cases reported to the World Health Organization from 28 countries ;666 deaths (case-fatality proportion: 8.4%). United States reports 355 cases from 40 states, no deaths. Laboratory testing to evaluate infection completed for 122 cases; six cases confirmed. Case reports for United States continue decrease; most cases associated with international travel. New interim surveillance case definition provides criteria to exclude reported cases subsequently found to have other causes of SARS-like symptoms. Clinical judgment should be used to guide management of patients.
5/14/03 MMWR Weekly | Update: SARS --- U.S., 2003
Provides update on reported SARS cases worldwide. As of May 14, 2003, a total of 7,628 cases reported to the World Health Organization from 28 countries; 587 deaths (case-fatality proportion 7.7%). Total cases account for 345 reported from 38 states in United States; 281 (81%)classified as suspect and 64 (19%) classified as probable. No deaths reported in United States. Most cases continue to be associated with international travel to areas affected by SARS. Provides CDC recommendations to prevent and control transmission for inbound travelers from areas with community transmission of SARS. CDC not recommending
quarantine for persons traveling from such areas.
5/9/03 MMWR Weekly | Update: SARS --- Singapore, 2003
Summarizes epidemiologic features of SARS in Singapore; discusses super spreaders and national prevention and control programs. As of April 30, 201 probable cases and 722 suspect cases reported; 25 patients died (case-fatality proportion: 12.5%). Surveillance indicates 76% of infections acquired in a health-care facility. Five patients categorized as super spreaders who were associated with transmissions to > 10 health-care workers, family and social contacts, or visitors to health care facilities. Infection-control measures include designating one hospital for SARS cases, expanding environmental practices to protect health-care workers, stopping general hospital visitation, and providing dedicated ambulance service. Infectious Disease Act amended, requiring more stringent quarantine measures and providing penalties for violations.
Morality rates of 8.4, 7.7 and 12.5% are reported here. I included the worst report, which was from Singapore, but the figures seem to be somewhat sketchy, since 722 suspect cases are not computed in the mortality rate. Therefore I'm more comfortable sticking with the 8.4 and 7.7% figures reported globally on the 14th and the 23rd of May.
15% is obviously an inflated figure. It's about double the actual mortality rate. Around 92% of people who contract SARS will recover. Obviously some age groups and other compromised patients profiles may experience elevated mortality, but I doubt mortality approaches 50% in any but the most compromised groupings, people who would be very weak to begin with.
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