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The genetic puppeteer (ever wonder why genetic twins look progressively different over time?)
Creation Magazine ^ | David White

Posted on 02/18/2009 8:49:26 PM PST by GodGunsGuts

The genetic puppeteer

by David White

Back in 2005 a group of researchers published a landmark study on a question that has long puzzled geneticists: why aren’t identical twins … identical? Considering that they have the same DNA sequence in each of their cells, it seems a bit strange that they often possess a number of physical differences, such as different fingerprints, and different susceptibilities to disease. This raises the question: if two people can have identical DNA sequences and yet be so different, is there more to our genetic blueprint than just DNA?...

(Excerpt) Read more at creationontheweb.com ...


TOPICS: Constitution/Conservatism; Culture/Society; News/Current Events; Philosophy
KEYWORDS: creation; epigenetics; evolution; genetics; intelligentdesign; twins
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To: krb

Vista and Explorer.


21 posted on 02/18/2009 9:27:36 PM PST by GodGunsGuts
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To: GodGunsGuts

Hmmm, don’t know why it won’t stream...but can you download it then play it? (it’s really awesome, BTW)


22 posted on 02/18/2009 9:30:10 PM PST by krb (Obama is a miserable failure.)
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To: krb

It just started playing. Boy did that thing take a long time to load. Thanks for the link!


23 posted on 02/18/2009 9:33:01 PM PST by GodGunsGuts
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To: GodGunsGuts
This raises the question: if two people can have identical DNA sequences and yet be so different

I wouldn't describe identical twins as "so different."

It's lost on me why the author thinks it is news that a variety of factors affect gene expression.

24 posted on 02/18/2009 9:48:18 PM PST by freespirited (Help save humanity. Cure the RINOvirus.)
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To: gondramB
It apparently starts in the pre-birth environment - the finger prints are apparently extremely similar but slightly different. Apparently difference in nutrition, womb position and blood pressure have slight effects on fingertip growth rate and thus cause tiny fingerprint differences.

You might be onto something there. My brother and I shared the same womb. I weighed one pound more at birth and through life I've always been 10+ pounds heavier.

Another thing, while in the womb, we decided to be just adorable... some things never change. :)

25 posted on 02/18/2009 9:55:28 PM PST by Diver Dave
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To: GodGunsGuts

Read the third one. So much misinformation or misunderstanding. Do the author and editors of that “journal” know the definition of references, because it has footnotes AND references in it.


26 posted on 02/18/2009 10:07:22 PM PST by Wacka
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To: GodGunsGuts

Funny thing, with epigenetics, maybe Lamarckianism looks to be vindicated in a very limited, highly qualified way, after all.

And another funny thing, there was a lot of tasty scientific goodness in that article without much fundamentalist preaching! I sure hope the good people at CMI are feeling well.


27 posted on 02/18/2009 10:08:51 PM PST by Mogwai (You say "far right" like that's a bad thing, Arlen!)
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To: freespirited

It’s not just some generic factor. The epigenetic code actually controls the genetic code. And, as it turns out, they are finding additional codes that make the genetic code perhaps the simplest code of them all.


28 posted on 02/18/2009 10:10:33 PM PST by GodGunsGuts
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To: Wacka

Fire away. I’m all ears.


29 posted on 02/18/2009 10:13:55 PM PST by GodGunsGuts
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To: Mogwai
You are quite right. The Evos who are clamoring for dumping Darwin in favor of a new evolutionary synthesis are most definitely giving Lamarckian evolution a second look. Of course, environmentally directed adaptation is not the only thing they are looking at. But the mere fact that they are dusting off Lamarck would have been considered heresy a few years ago (and still is by many neo-Darwinists, such as Richard Darwkins et al).
30 posted on 02/18/2009 10:22:09 PM PST by GodGunsGuts
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To: GodGunsGuts

Most of this stuff in this article has been known for years. The UTRs he mentioned are called introns. They were discovered over 30 years ago. The people who found them won a Nobel in 1993 or 1994. Where I worked then was lucky enough to had booked one of the winners for a lecture that was scheduled the week after he won. The entire genome is not transcribed. A lot of stuff like that from someone without a firm grasp of the field. The author is a botanist that spent a lot of time doing missionary work, not someone with a molecular biology background.

About the DNA replication, I actually developed a method (about 20 years ago) to map which regions had replication origins and in which directions the DNA replicated. Other labs used my method soon after to show that DNA replication occurred in nonspecific regions in human DNA. Again, what is your background or his in molecular biology???


31 posted on 02/18/2009 10:47:17 PM PST by Wacka
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To: GodGunsGuts


Don't forget. I get to wear the watch on Thanksgiving.
32 posted on 02/18/2009 10:50:28 PM PST by Liberty Valance (Keep a Simple Manner for a Happy Life ;o)
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To: Wacka
==The UTRs he mentioned are called introns.

Wow, wrong right out of the box. You are obviously an expert. LOL


33 posted on 02/18/2009 10:54:51 PM PST by GodGunsGuts
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To: Wacka

PS Could it be that you don’t know the difference between transcription and translation? I think I’ll stick with the botanist/missionary.


34 posted on 02/18/2009 10:58:42 PM PST by GodGunsGuts
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To: GodGunsGuts

The way the author describes UTRs in the article, he makes no distinction between the 5’ and 3’ UTRs and introns. Both were known even before introns. It was known that there had to be regions 5’ (upstream) where the translation machinery (ribosomes and associated proteins) had to bind to start synthesizing proteins. More recently it was found that the 3’ end contains sequence motifs (not necessarily specific bases) to tell the cell to stop transcription . These are likely the 3D structure the mRNA makes and not specifically the sequence. You have this idea that this “ancient” history is somehow new. None of this repudiattes evolution at all.


35 posted on 02/18/2009 11:10:33 PM PST by Wacka
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To: Wacka

Wrong again. Williams’ paper is covering recent and groundbreaking discoveries by project ENCODE. Next time you say you have read something, you might want to consider actually reading it. The “ancient history” (the only part you apparently read) is covered at the beginning of the paper. Williams then goes on to demonstrate how our antiquated notions with respect to the genome have been RADICALLY changed by project ENCODE.


36 posted on 02/18/2009 11:22:05 PM PST by GodGunsGuts
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To: Wacka

PS Way to NOT admit your error.


37 posted on 02/18/2009 11:23:20 PM PST by GodGunsGuts
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To: GodGunsGuts

`What is my error snoogums?


38 posted on 02/18/2009 11:26:57 PM PST by Wacka
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To: GodGunsGuts

Introns are also UTRs. They are transcribed, but not translated. UTR in the field means UnTranslated Regions. DNA is transcribed to RNA and then the RNA is translated to protein. He said that.
It seems that you don’t know what transcription and translation are.
Again, what is your biology background snoogums??


39 posted on 02/18/2009 11:28:08 PM PST by Wacka
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To: Wacka

PSS What do you suppose the discovery that the genome is 93%+ functional will do to all those phylogenetic trees that the Darwinists have constructed based on a neutral rate of mutation?


40 posted on 02/18/2009 11:28:35 PM PST by GodGunsGuts
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