New vaccine may be effective against all coronaviruses

London -- A team of scientists from the world’s leading universities have developed a new all-in-one vaccine that they hope can protect humans against a broad range of coronaviruses, including ones that are yet to emerge.

The research published in ‘Nature Nanotechnology’ on Monday is based on a new approach to vaccine development called “proactive vaccinology”, where scientists build a vaccine before the disease-causing pathogen even emerges, which has shown promising results in mice.

The study by the Universities of Oxford and Cambridge in the UK and Caltech in the US says the vaccine works by training the body’s immune system to recognise specific regions of eight different coronaviruses, including SARS-CoV-2 which caused the COVID-19 outbreak, and several that are currently circulating in bats and have potential to jump to humans and cause a pandemic. “Our focus is to create a vaccine that will protect us against the next coronavirus pandemic, and have it ready before the pandemic has even started,” said Rory Hills, a graduate researcher in the University of Cambridge’s Department of Pharmacology and first author of the report.

For example, the new vaccine does not include the SARS-CoV-1 coronavirus, which caused the 2003 SARS outbreak, yet it still induces an immune response to that virus. “We’ve created a vaccine that provides protection against a broad range of different coronaviruses – including ones we don’t even know about yet,” said Hills.

Key to its effectiveness is that the specific virus regions the vaccine targets also appear in many related coronaviruses. By training the immune system to attack these regions, it gives protection against other coronaviruses not represented in the vaccine, including ones that haven’t even been identified yet.

“We don’t have to wait for new coronaviruses to emerge. We know enough about coronaviruses, and different immune responses to them, that we can get going with building protective vaccines against unknown coronaviruses now,” said Professor Mark Howarth in the University of Cambridge’s Department of Pharmacology, senior author of the report.

“Scientists did a great job in quickly producing an extremely effective COVID vaccine during the last pandemic, but the world still had a massive crisis with a huge number of deaths. We need to work out how we can do even better than that in the future, and a powerful component of that is starting to build the vaccines in advance,” he said.

The new ‘Quartet Nanocage’ vaccine is based on a structure called a nanoparticle – a ball of proteins held together by incredibly strong interactions. Chains of different viral antigens are attached to this nanoparticle using a novel “protein superglue”. Multiple antigens are included in these chains, which trains the immune system to target specific regions shared across a broad range of coronaviruses. The latest study demonstrated that the new vaccine raises a broad immune response, even in mice that were pre-immunised with SARS-CoV-2. The new vaccine is much simpler in design than other broadly protective vaccines currently in development, which the researchers believe should accelerate its route into clinical trials.

The underlying technology that the scientific collaboration has developed also has potential for use in vaccine development to protect against many other health challenges. It is said to improve on previous work, by the Oxford and Caltech groups, to develop a novel all-in-one vaccine against coronavirus threats.

According to experts, conventional vaccines include a single antigen to train the immune system to target a single specific virus, which may not protect against a diverse range of existing coronaviruses or against pathogens that are newly emerging.

The latest research was funded by the UK’s Biotechnology and Biological Sciences Research Council.

ALTERNATIVE SAFE WAYS TO KEEP YOUR RESISTANCE UP & FIGHT COVID -19. AS WELL AS “VARIATIONS” AND A HOST OF OTHER INFECTIONS INCLUDING THE FLU. SO FAR, WHOEVER BEEN USING THIS REGIME, EITHER DID NOT CATCH THE BUG AND IF THEY DID; SHOOK IT OFF PRETTY QUICK.

THIS REGIME WILL “NOT” PREVENT YOU FROM CATCHING ANY CRAZY VIRUS BUT IF YOU DO, IT WILL HELP TO SHAKE IT OFF FAIRLY QUICK, FOR SOME PEOPLE IT WORKS SO WELL THEY DON’T EVEN FEEL THEY GOT IT. BESIDES IT WILL ALSO WORK AGAINST OTHER RELATED VIRUSES; NOT ONLY THAT, BUT WILL BENEFITS YOUR HEALTH AS WELL, IF YOU CATCH THIS VIRUS OR NOT. EITHER WAY YOU WIN. ALONG WITH IT YOU WILL HAVE ACQUIRED NATURAL IMMUNITY WITHOUT ANY SHORT OR LONG TERM ADVERSE SIDE EFFECTS.

There are other ways and means to enhance your resistance against viruses including that by now infamous covid-19 virus aside from taking any of these “Quick” developed vaccines utilizing a messenger RNA. So far science has not evolved far enough yet to be certain how the human body will react many month or years down the road once we start tinkering around with our immune system and how our bodies will react should we encounter mutated strains of similar viruses.

Below is a list of vitamins as well as nutrients SUGGESTED BY A PHYSICIAN to enhance your resistance, they are harmless and even beneficial to your body unless someone goes crazy and over doing it. Even so they will NOT protect you from getting any specific viruses; neither will any of those new “QUICK” developed vaccines. But not only will they make you more resistant but also help you to overcome the effects of such a virus more quickly, should you have bad luck getting it. And once you are over it, your natural immune system will take over and protect you considerably better than any vaccination, this according to a statement by Merck. The CATCH is to have these vitamins/nutrients in your system BEFORE you think you have caught this virus, as time is of essence so your system starts fighting the virus BEFORE it gets a chance to do any damage.

A suggestion to the wise, take some time and read up on each of these suggested components which is freely available on the internet.

Vitamin D-3 — Vitamin D supplements are readily available and one of the least expensive supplements on the market. All things considered, vitamin D optimization is likely the easiest and most beneficial strategy that anyone can do to minimize their risk of COVID-19 and other infections, and can strengthen your immune system in a matter of a few weeks.

N-acetyl cysteine (NAC) — NAC is a precursor to reduced glutathione, which appears to play a crucial role in COVID-19. According to one literature analysis,7 glutathione deficiency may actually be associated with COVID-19 severity, leading the author to conclude that NAC may be useful both for its prevention and treatment. For best results should always be taken with two to three times the amount of vitamin C. DO NOT GET IT MIXED UP WITH ACETYL L-CARNITINE. AS A REMINDER, DO NOT LEAVE OUT NAC AS IT IS AN IMPORTANT COMPONENT OF THIS REGIME.

Zinc — Zinc plays a very important role in your immune system’s ability to ward off viral infections.

Like vitamin D, zinc helps regulate your immune function8 — and a combination of zinc with a zinc ionophore, like hydroxychloroquine or quercetin, was in 2010 shown to inhibit SARS coronavirus in vitro. In cell culture, it also blocked viral replication within minutes.9 Importantly, zinc deficiency has been shown to impair immune function.

Melatonin — Boosts immune function in a variety of ways and helps quell inflammation. Melatonin may also prevent SARS-CoV-2 infection by recharging glutathione11 and enhancing vitamin D synthesis, among other things.

Vitamin C — A number of studies have shown vitamin C can be very helpful in the treatment of viral illnesses, sepsis and ARDS,12 all of which are applicable to COVID-19. Its basic properties include anti-inflammatory, immunomodulatory, antioxidant, antithrombotic and antiviral activities. At high doses, it actually acts as an antiviral drug, actively inactivating viruses. Vitamin C also works synergistically with quercetin.

Quercetin — Quercetin is the most abundant dietary flavonoid, found enriched in cranberry, onions, blueberry, apples, and tea. As a polyphenol compound, it is ALSO considered a potent iron chelator. A powerful immune booster and broad-spectrum antiviral, quercetin was initially found to provide broad-spectrum protection against SARS coronavirus in the aftermath of the 2003 SARS epidemic,14,15,16 and evidence suggests it may be useful for the prevention and treatment of SARS-CoV-2 as well. Not only that but quercetin also acts as an ionophore for zinc similar to hydroxychloroquine, in a matter of speaking it will unlock the cells to let the zinc in where it can attack the virus . It is also a good pain killer and better for the human body than Aspirin, what helps to subdue arthritis pain. I is good for sinus infection, in other words if you happen to have a runny nose. Past studies have also shown that quercetin showed potent ability against some viruses, such as enterovirus, Middle East respiratory syndrome coronavirus (MERS-CoV), and the severe acute respiratory syndrome coronavirus (SARS-CoV).

B vitamins — B vitamins can also influence several COVID-19-specific disease processes, including17 viral replication and invasion, cytokine storm induction, adaptive immunity and hypercoagulability.

LYSINE
When lysine blocks enzymes it inhibits the spread of the virus in the body by limiting the effect of weakening this connective tissue. An adult may take 2-3000 mg per day of lysine while trying to beat a virus.

SUGGESTED DOSAGE

All components as suggested are individually obtained and freely available and if used with some common sense are not harmful and if anything beneficial to your health. However it is a good idea and highly recommended to read up on each component, as there is plenty of information available on the internet. You may be surprised to find out and learn about the many benefits they provide to your health.
Here is a suggested approximate dosage for each.

Vitamin D-3 1500 IU

Malatonine 3mg to 6mg suggested about one hour before you go to sleep.

QUERCETIN 500 mg to 1000 mg

NAC 500 mg to 1000 mg (N-Acetyl-Cysteine)

Zinc 50 mg

Vitamin C 1500 mg or MORE !! but always should be to two three times as much as NAC

LYSINE

1500 mg to 3000mg

Vitamin B complex

So far whoever has been taking this regime of supplements and may have had a brush with this virus, shook it off fairly easily and quickly and the most important thing was that in the process such a person also acquired natural immunity. Not only that but at the same time this regime also helps to ease the effects of the regular flu.

Some of user’s comments:

Latest J&J Vaccine Info: Alex Berenson
4/15/2021, 10:49:29 AM • 27 of 28
Chauncey Gardiner to saintgermaine
Good post.
I have been on that same vitamin regimen since April 2020 along with approx 25 friends/family members. All of us socially active...restaurants, church, weddings, travel, etc. In other words, we’ve not changed our lives the past year. Not a one of us has tested positive and not a one has even had a cold. I’ve added hydroxychloroquine 200mg each Sunday starting about 6 mos ago.

Mississippi man partially paralyzed, unable to talk after J&J vaccine
4/16/2021, 6:48:45 PM • 37 of 39
upchuck to saintgermaine

Excellent regimen. Pretty much what I’ve been doing. I have been taking 5000 iu of Vit D3 per day for years and have never been sick (thank you Lord). With the China Virus, I upped it to 10,000 iu. I think zinc and quercetin are the most important.
10,570 DEAD 405,259 Injuries: European Database of Adverse Drug Reactions for COVID-19 “Vaccines”

5/21/2021, 7:41:23 AM • 52 of 52
jimjohn to saintgermaine
Been on similar regimens since August of 2020. Attended parties public events even a professional football game. Oh, and I fall in the high-risk category. Also posted recently about hearing friends and associates who’ve taken the jab complain about the after effects. Also note that my position would not recommend that I take this experimental vaccine.

Trump Girl Kit Cat to saintgermaine
My Doc put myself and EVERY patient he had on Quercetin, C, D3, Zinc, and NAC from day one he has not had ONE SINGLE patient catch this virus, I also put my 92 year old mom on it I NEVER miss a day!! My mom had a small stroke about 4 months ago neither of us vaccinated I had to take her to emergency and was worried because hospitals are an absolute petrie dish of germs we both spent 4 days in the hospital no masks in room AND we both came home just fine this supplement regimen works!!!
12/30/2021, 1:21:53 PM · 39 of 43

12/30/2021, 1:21:53 PM · 39 of 43
Utah Binger to saintgermaine
NAC is fabulous. I was suffering what I thought was Bronchitas for about two weeks. Might have been covid. Anyway a neighbor gave me a bottle and said to take two in morning and two at night. In one day Bronchitas was gone.

1/4/2022, 6:29:59 AM · 16 of 17
Caipirabob to saintgermaine; aMorePerfectUnion
I have done this supplement regiment with my wife for two years now, going into our third soon. We are as ethnically different as it gets but we have flown 8 times and never missed a happy hour that was convenient, dined out constantly, visited family and lived our lives as normally as possible, perhaps even moreso.
I’ve had three bouts of illness impacting my ears and sinus, but I have a condition that makes that a normal event. It actually occurred less than normal than in the previous 20 years.We did not vaccinate for personal reasons. I credit blessings and the regiment of supplements in helping us avoid the chicom plague and pray it continues to do so.

1/4/2022, 1:41:18 PM · 16 of 18
copaliscrossing to saintgermaine
When I got Covid, my doctor immediately put me on 10,000 IU’s of D3 per day even though I was already taking 5,000 per day. He also recommended NAC. I had never heard of NAC before he recommended it and he only recommended it because I have a bit of an issue with chronic bronchitis. Bought some NAC and have been taking it ever since. That stuff works PERIOD. I think that is why the FDA is bullying a lot of retailers (including Amazon) with fines and the such. So the retailer pulled the NAC from their shelves. Sad, because I really believe the reason the FDA is pulling it is because it WORKS!

• New COVID Variants Are Circulating. Here’s What to Know.
11/8/2022, 12:25:07 PM · 50 of 51
FlyingEagle to Saintgermain
Amazing. I take all that stuff. When I got Covid, I took The Medications Whose Names Must Not Be Spoken. Worked great.
12/15/2023, 1:26:54 PM · 37 of 49
Uncle Miltie to Saintgermain
I’m on all those except lysine.
My teacher wife has been sick three times this fall. I haven’t been sick once.
Saintgermain
About 14 years ago when the H-1 N-1 pig, bird & Human flu made its rounds and the question for vaccination came up, someone on FR suggested to take N-acetyl-cysteine which should be taken with at least two times as much vitamin C instead of getting any shots. I have been using it ever since, with excellent results as it will boost your level of glutathione which in turn makes you more resistant to a variety of infections. If used in combination with some of the suggested supplements as suggested in this article it works even better.

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