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Why Female Mice Should be Used in Research
Laboratory Equipment.com ^ | 3-7-23 | Michelle Taylor

Posted on 03/08/2023 8:28:48 AM PST by fishtank

Why Female Mice Should be Used in Research

March 07, 2023

Michelle Taylor

For over 50 years, researchers have preferentially used male mice in experiments, in part due to concern that the hormone cycle in females would cause behavioral variation that could negatively impact results. Over time, this practice has resulted in a poorer understanding of the female brain, likely contributing to the misdiagnosis of mental and neurological conditions in women, as well as the development of drugs that have more side effects for women.

(Excerpt) Read more at laboratoryequipment.com ...


TOPICS: Culture/Society
KEYWORDS: mice
From the article:

"“This bias starts in basic science, but the repercussions are rolled into drug development, and lead to bias in drugs being produced, and how drugs are suited for the different sexes,” said Dana Levy, a research fellow in neurobiology at Harvard Medical School (HMS).

Now, a new study led by Levy has not only turned the long-held, sexist assumption on its head but has demonstrated the opposite—male mice are the ones that exhibit excessive behavioral variation that can harm research results."

1 posted on 03/08/2023 8:28:48 AM PST by fishtank
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To: fishtank

What if the male mice identify as female?


2 posted on 03/08/2023 8:30:14 AM PST by Tell It Right (1st Thessalonians 5:21 -- Put everything to the test, hold fast to that which is true.)
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To: fishtank

Heh ... male mice experimented on, women hardest hit.


3 posted on 03/08/2023 8:30:15 AM PST by Rurudyne (Standup Philosopher)
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To: fishtank

What about Trans-Mice?..........................


4 posted on 03/08/2023 8:30:42 AM PST by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: fishtank

A recent news article said that there are 73 genders. Yet the author persists in identifying only 2 genders. The author is either stupid or a hater.


5 posted on 03/08/2023 8:33:52 AM PST by Leaning Right (The steal is real.)
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To: fishtank
Over time, this practice has resulted in a poorer understanding of the female brain


6 posted on 03/08/2023 8:36:34 AM PST by Magnum44 (...against all enemies, foreign and domestic... )
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Comment #7 Removed by Moderator

To: fishtank

I thought this was gonna be a joke.....


8 posted on 03/08/2023 8:44:28 AM PST by Scarlett156 (My aluminum baseball bat keeps telling me it wants to talk to J3rry S3infeld. )
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To: fishtank

No mention of the elephant in the room, that mice poorly represent humans in many ways. Their immune system, their neurology, their GI tract, etc. So, “mouse studies” have a high likelihood of being invalid.

The closest animal to the human immune system is the ferret, so much so that they are seen as the “canary in a coal mine” animal for epidemics.

As far as chromosomal pairs go, humans with 46, are between Arabian Coffee, with 44, and Water Buffalo or Tobacco, with 48.

I didn’t say this is easy.


9 posted on 03/08/2023 8:58:08 AM PST by yefragetuwrabrumuy ("All he had was a handgun. Why did you think that was a threat?" --Rittenhouse Prosecutor)
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To: Red Badger

“What about Trans-Mice?”

They’re ahead of us. They all have used the same spot in the cage for years.

wy69


10 posted on 03/08/2023 8:58:36 AM PST by whitney69
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To: fishtank

AH! So the distinction male/female matters in mice! But not in humans!

A sure sign of insanity is the refusal to drop from one’s mind one of two contradictory assertions.


11 posted on 03/08/2023 9:03:35 AM PST by I want the USA back (News media and democrats are pond scum. My pronouns: Haha, heehee, hoho, hoo hoo. )
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That’s great in theory, but in reality there is absolutely no way to distinguish which ones are male versus female


12 posted on 03/08/2023 9:05:33 AM PST by dsrtsage ( Complexity is just simple lacking imagination)
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To: fishtank

Yet for all of the shortcomings in research, women still tend to live significantly longer than men.


13 posted on 03/08/2023 9:07:32 AM PST by hanamizu
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To: fishtank

I vaguely recall reading about a study done in the 80’s, where researchers tried to see if there was a correlation between diet and uterine cancer. Throughout the study, none of the subjects developed uterine cancer, so the conclusion was that diet had no effect on uterine cancer rates.

It was only when you dig deep into the details of the study that one glaring problem turned up:

Every single participant was male.

Raise your hand if you’re shocked that a group of people who don’t have uteruses never developed cancer of the uterus?


14 posted on 03/08/2023 9:46:30 AM PST by Ellendra (A single lie on our side does more damage than a thousand lies on their side.)
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To: Tell It Right

Did anybody remember to ask the mice xe/xer pronouns? Did a biologist identify the women mice?

This is serious business these days. Just cannot be too careful about these things, can we?


15 posted on 03/08/2023 9:54:01 AM PST by ProtectOurFreedom (There is lots of money and power in Green Communism and we all know where Communism ends.)
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To: Magnum44

16 posted on 03/08/2023 10:39:06 AM PST by Boogieman
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To: yefragetuwrabrumuy

Don’t forget, pigs are the animals with an epidermus and cooling system most like humans, while cows are the animals that have the same blood groups as humans.


17 posted on 03/08/2023 10:41:08 AM PST by Boogieman
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To: fishtank
My take from the article is that human males and females are no more complex than rodent males and females. If so, how come rodent females are not demanding equality with rodent males?
18 posted on 03/08/2023 12:10:07 PM PST by kickstart ("A gun is a tool. It is only as good or as bad as the man who uses it" . Alan Ladd in 'Shane' )
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