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University of Washington creates new COVID-19 vaccine
mynw ^

Posted on 04/26/2022 4:01:28 PM PDT by algore

A COVID-19 vaccine, developed at the University of Washington School of Medicine, has been proven safe and effective in late-stage clinical testing.

SK bioscience developed the vaccine, named GPB510, alongside the UW School of Medicine at the school’s facilities. The two are seeking South Korea’s authorization for use within a month. The company is seeking review and approval of the vaccine from the Korean Ministry of Food and Drug, and then will seek pre-authorization from the World Health Organization.

South Korea has agreed to buy 10 million doses.

SK Bioscience has developed vaccines since 2008, with the cell-cultured trivalent flu vaccine in 2015, followed by the cell-cultured quadrivalent flu vaccine, the zoster vaccine, and the varicella vaccine. In 2020, the company pivoted into the global market with the development of the COVID-19 vaccine.

Unlike the earliest approved vaccines for COVID-19 that make use of mRNA, viral vectors, or an inactivated virus, GPB510 is made of proteins that form tiny particles studded with fragments of the pandemic coronavirus. These nanoparticles were designed by scientists at UW Medicine and advanced into clinical trials by SK bioscience and GlaxoSmithKline with financial support from the Coalition for Epidemic Preparedness Innovations.

“The advantage of the nanoparticle vaccine over a traditional protein subunit vaccine is that, by presenting the antigen in this repetitive array, you will elicit a stronger immune response, which should translate to better protection,” said Neil King, assistant professor of biochemistry for the UW School of Medicine, in a news release.

King also stressed that a protein nanoparticle vaccine will be easier to produce and store. It’s effective at low doses and simple to make on a large scale while not requiring deep freezing in order to become stable.

GPB510, now fully approved by regulators, will be available through COVID-19 Vaccines Global Access, (COVAX), a worldwide initiative aimed at equitable access to COVID-19 vaccines directed by the GAVI vaccine alliance, the Coalition for Epidemic Preparedness Innovations, and the World Health Organization.

“We know we have more than 2 billion people worldwide that have not received a single dose of vaccine,” said David Veesler, associate professor of biochemistry at UW School of Medicine, in a news release. “If our vaccine is distributed through COVAX, it will allow it to reach these people that need to have access to doses.”

This type of vaccine has been researched since 2016, as scientists in the King lab at the UW School of Medicine began developing a strategy to design proteins that self-assemble into precise spherical particles. This research showed that these nanoparticles could be decorated with proteins from a virus.

Researchers from the two labs worked together in the earliest months of the COVID-19 pandemic to design a protein nanoparticle decorated with 60 copies of the Spike protein receptor-binding domain. The designed nanostructure mimics the repetitive nature of proteins on the surface of viruses, a property that the immune system responds strongly to.

In initial animal studies reported in late 2020, the nanoparticle vaccine was found to produce high levels of virus-neutralizing antibodies at low doses. These antibodies target several different sites on the coronavirus Spike protein, a desirable quality that may enhance protection against future coronavirus variants.

“The hope with those vaccines is that we will prevent the next pandemic instead of responding to it,” said King. “And so, the current vaccine and meeting its primary endpoint suggests that this technology may be a viable route forward.”


TOPICS: News/Current Events
KEYWORDS: covid; covid19; vaccine

1 posted on 04/26/2022 4:01:28 PM PDT by algore
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To: algore

And I won’t take this one either.


2 posted on 04/26/2022 4:03:12 PM PDT by EvilCapitalist (I pledge allegiance to Hedy Lamarr)
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To: algore

I have this thing God gave me called an immune system.
Eat healthy, take supplements, exercise, get sleep, and meditate/pray.


3 posted on 04/26/2022 4:03:21 PM PDT by EEGator
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To: algore

the scale upon how to rate the effectiveness of this product? How much resistance it gets from the establishment!! I would say...


4 posted on 04/26/2022 4:05:15 PM PDT by sit-rep ( )
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To: algore
Brought to you by the same University which hyped lockdowns, [anti]social distancing, school closures, and universal mask wearing through their "models" in 2020.

Don't drink their Kool-Aid!

5 posted on 04/26/2022 4:05:45 PM PDT by lightman (I am a binary Trinitarian. Deal with it!)
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To: algore

Um, maybe, but I’ve heard this claim before and it turned out to be a lie. So with extraordinary claims [like a cold vaccine] there must be extraordinary evidence. Even then, as a pure-blood whose already had the Rona, there’s virtually no reason to take it.


6 posted on 04/26/2022 4:06:18 PM PDT by TonyinLA ( I don't have sufficient information to make an informed opinion said no lefty ever.)
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To: algore

The other ones aren’t killing people fast enough.


7 posted on 04/26/2022 4:06:37 PM PDT by Trillian
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To: EEGator

That’s a good plan.


8 posted on 04/26/2022 4:18:01 PM PDT by ealgeone
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To: algore
"designed by scientists at UW Medicine and advanced into clinical trials by SK bioscience and GlaxoSmithKline with financial support from the Coalition for Epidemic Preparedness Innovations."

"CEPI was founded in Davos by the governments of Norway and India, the Bill & Melinda Gates Foundation, Wellcome, and the World Economic Forum."

9 posted on 04/26/2022 4:18:32 PM PDT by outofsalt (If history teaches us anything, it's that history rarely teaches anything.)
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To: ealgeone

Thank you. I highly recommend it.


10 posted on 04/26/2022 4:19:48 PM PDT by EEGator
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To: algore

What’s Covid19?


11 posted on 04/26/2022 4:29:40 PM PDT by BenLurkin ((The above is not a statement of fact. It is either opinion, or satire. Or both.))
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To: lightman

No more shots for me.


12 posted on 04/26/2022 4:33:03 PM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: algore

It sounds good. Very innovative.

I just don’t understand why anyone would take a new medication for a disease with a 99.97% survival rate. I wouldn’t take an aspirin for that.


13 posted on 04/26/2022 4:35:14 PM PDT by TigersEye (Is it time for a general strike yet?)
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To: carriage_hill

I’m an unboosted deplorable and intend to stay that way.


14 posted on 04/26/2022 4:36:21 PM PDT by lightman (I am a binary Trinitarian. Deal with it!)
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To: BenLurkin
What’s Covid19?

I am not a Fauci, how could I possibly know?

But It sounds really really scary


15 posted on 04/26/2022 4:45:48 PM PDT by algore
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To: carriage_hill

No more for me either.


16 posted on 04/26/2022 4:56:57 PM PDT by telescope115 (Proud member of the ANTIFAuci movement. )
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To: EvilCapitalist

Neither will I-raised in the naturalist lifestyle and I’ve lived it ever since-no drugs, no processed food-organic only paleo diet, vitamins and supplements, workouts, physical job and no extra pounds makes a strong immune system, so no vaccines for me, thanks-and I already had a mild case of the Wuhan in 2020, when everyone was all masked up-no mask since and no problems...

This new “vaccine” is just more covidian koolaid with a new flavor...


17 posted on 04/26/2022 5:16:39 PM PDT by Texan5 ("You've got to saddle up your boys, you've got to draw a hard line"...)
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To: outofsalt

Now there’s a trustworthy group!


18 posted on 04/26/2022 5:18:33 PM PDT by Tunehead54 (Nothing funny here ; - )
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To: algore

Another snake oil.


19 posted on 04/26/2022 5:31:28 PM PDT by LibFreeUSA
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To: algore

“has been proven safe and effective”

But it has to be safe, effective and FREE!


20 posted on 04/26/2022 5:43:57 PM PDT by Neverlift (When someone says "you just can't make this stuff up" odds are good, somebody did.)
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