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AstraZeneca announces 'robust' results from anti-COVID drug trial
https://medicalxpress.com ^ | November 18, 2021 | Staff

Posted on 11/18/2021 12:14:10 PM PST by Red Badger

This transmission electron microscope image shows SARS-CoV-2 -- also known as 2019-nCoV, the virus that causes COVID-19 -- isolated from a patient in the US. Virus particles are shown emerging from the surface of cells cultured in the lab. The spikes on the outer edge of the virus particles give coronaviruses their name, crown-like. Credit: NIAID-RML

Pharmaceutical giant AstraZeneca on Thursday announced that clinical trials of an antibody-based COVID-19 drug had shown robust efficacy and long-term prevention.

The Anglo-Swedish laboratory follows in the footsteps of US firms Merck and Pfizer, which announced in October and early November respectively that they had developed drugs that could prevent severe forms of the disease, and that could be taken at the first sign of symptoms.

The AstraZeneca drug AZD7442, made from a combination of two antibodies, has been undergoing final stage clinical trials to assess its safety and efficacy.

A six-month follow-up trial "showed robust efficacy from a one-time intramuscular (IM) dose of the long-acting antibody (LAAB) combination", it said in a statement.

One 300mg IM dose reduced the risk of developing symptomatic COVID-19 compared to placebo by 83 percent, it added.

More than 75 percent of participants had co-morbidities that put them at high risk for severe COVID-19 if they were to become infected, but no severe cases were recorded.

Another trial to test its efficacy in treating those already suffering from "mild to moderate" COVID symptoms showed that one 600mg IM dose reduced the risk of developing severe illness or death by 88 percent.

"These compelling results give me confidence that this long-acting antibody combination can provide my vulnerable patients with the long-lasting protection they urgently need to finally return to their everyday lives," said Hugh Montgomery, professor of intensive care medicine at University College London.

"Importantly, six months of protection was maintained despite the surge of the Delta variant among these high-risk participants who may not respond adequately to vaccination."

AstraZeneca said the full results of both trials would be submitted for publication to a peer-reviewed medical journal.

It has already submitted an application to US regulators for approval of the drug to treat COVID-19.

AstraZeneca's separate COVID vaccine, developed with the University of Oxford, helped enable Britain's speedy COVID vaccination drive after it was approved in December 2020.


TOPICS: Business/Economy; Culture/Society; Foreign Affairs; Government
KEYWORDS:

1 posted on 11/18/2021 12:14:10 PM PST by Red Badger
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To: Red Badger

Astra-Zeneca. A name we can trust. /s


2 posted on 11/18/2021 12:15:36 PM PST by Seruzawa ("The Political left is the Garden of Eden of incompetence" - Marx the Smarter (Groucho))
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To: Red Badger

This stuff should a been done long time ago. Note:patentable treatment. 3 years from now...they will demonstrate that there are other chemical compounds...unpatentable ones, that work also...


3 posted on 11/18/2021 12:20:52 PM PST by Getready (Wisdom is more valuable than gold and diamonds, and harder to find.)
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To: Red Badger

“Importantly, six months of protection was maintained despite the surge of the Delta variant”......

That’s about as good as the current crop of vaxes. One shot and you’re done and it’s effective through the early stages of the disease.

Maybe if they grant fowxi some stock options, it’ll get approved here one day.


4 posted on 11/18/2021 12:33:02 PM PST by Ceebass (USA RIP 1776-2021)
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To: Red Badger

Red Badger: This transmission electron microscope image shows SARS-CoV-2 — also known as 2019-nCoV, the virus that causes COVID-19 — isolated from a patient in the US.

Was it you that told us the SARS-CoV-2 virus has never been isolated?


5 posted on 11/18/2021 12:33:12 PM PST by DugwayDuke (Most pick the expert who says the things they agree with.)
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To: Red Badger

Why no ads for the vaccines on the tele? I see so many for other meds. None for the Covid.


6 posted on 11/18/2021 12:33:42 PM PST by TornadoAlley3 ( I'm Proud To Be An Okie From Muskogee)
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To: DugwayDuke

Probably...............


7 posted on 11/18/2021 12:34:04 PM PST by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: TornadoAlley3

Too many lawyer ads..................


8 posted on 11/18/2021 12:36:25 PM PST by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: Red Badger

Yes, what do they call it? iVermectin instead of Ivermectin? A TOTALLY DIFFERENT DRUG than that awful ‘horse paste’.

</sarc>


9 posted on 11/18/2021 12:37:11 PM PST by A Formerly Proud Canadian (Ceterum autem censeo Justinius True-dope-us esse delendam)
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To: Red Badger

So a traditional vacc approach…no genetic modification?


10 posted on 11/18/2021 2:03:00 PM PST by silverleaf (“Freedom ultimately means the right of other people to do things that you disagree with”. T. Sowell )
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To: Red Badger

Hey Rocky, watch me pull a rabbit out of muh hat ...

Again???????


11 posted on 11/18/2021 2:03:49 PM PST by Cboldt
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To: silverleaf

For me...must not utilize aborted fetal tissue/cells in the research, development and production. Must not alter human DNA.

I would consider a traditional vaccine made from inactivated particles of the virus just like the influenza vax.

Somethings really really creepy about how all these people, governments, corporations are pushing relentlessly these mRNA concoctions.


12 posted on 11/18/2021 2:11:20 PM PST by servantboy777
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To: Red Badger

“Robust” = killing even more people.


13 posted on 11/18/2021 2:15:27 PM PST by MayflowerMadam (When government fears the people, there is liberty.)
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To: Red Badger

Red Badger wrote: “Probably...............”

I appreciate your admission. But, don’t think you’re the Lone Ranger. IIRC, saying SARS-CoV-2 had never been isolated is a claim that has been quite popular in anti-vaxxer mythology.

This is a major problem on the web. Not just vaccine/virus/vaxxer sites but quite common in many other places and arguments. Some website will make a claim and it’s immediately pasted into multiple sites. No one bothers to validate the claim as long as it fits their preconceived narrative. (Note, I’m not accusing anti-vaxxers solely. Pro-vaxxers do it too.)


14 posted on 11/18/2021 2:31:38 PM PST by DugwayDuke (Most pick the expert who says the things they agree with.)
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To: DugwayDuke

(Note, I’m not accusing anti-vaxxers solely. Pro-vaxxers do it too.)

*************

IMO that is pretty much true all across the board regardless of
the many avenues in life. Opinions vary and some get testy. JMO


15 posted on 11/18/2021 2:38:33 PM PST by deport
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To: Red Badger

didnt see anything about side effects plus no long term testing


16 posted on 11/18/2021 3:58:16 PM PST by joshua c (Dump the LEFT. Cable tv, Big tech, national name brands)
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To: Red Badger
As I've posted here before:


FJB

17 posted on 11/18/2021 4:59:26 PM PST by upchuck (The longer I remain unjabbed with the clot-shot, the more evidence I see supporting my decision.)
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To: Red Badger

Read later.


18 posted on 11/18/2021 5:44:58 PM PST by NetAddicted ( Just looking)
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To: DugwayDuke
...SARS-CoV-2 has never been isolated...

At first inspection, that statement cannot be true, for if it had "never been isolated" we would not know that it even existed or what it was, much less have a name. So people are spreading a statement that is demonstrably illogical from the beginning.

Kind of like 'Dark Matter' and 'Dark Energy' in the astrophysical arena, they don't know what it is, have never seen it, never measured it and never held it in their hands, but it exists and they are sure of it.

And it plugs holes in their 'theories' rather nicely............... .................................

19 posted on 11/19/2021 5:39:00 AM PST by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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