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Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination ?
Journal of Infection ^ | August 09, 2021 | Nouara Yahi, Henri Chahinian, Jacques Fantini

Posted on 08/13/2021 7:26:07 AM PDT by MMaschin

However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity. Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors).

(Excerpt) Read more at journalofinfection.com ...


TOPICS:
KEYWORDS: ade; covid19; vaccines
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While it appears that the vaccines worked well against the original version of the virus, it appears that they are causing ADE (Antibody Dependent Enhancement) when presented with the Delta variant.
1 posted on 08/13/2021 7:26:07 AM PDT by MMaschin
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To: MMaschin

The vaccine industry is pure evil and fraudulent

Every single white coat lab bull crap they come up with about antibodies and immunity is completing other nonsense

All big Pharma wants to do is put on a big show and make money and they actually really could care less about human health and in fact don’t mind if they destroy people in their lives

Right now we’re in the midst of the communist in their implementation of the great reset and they’re trying to use the vaccine industry to create a medical call me to security state

Put it simply we must start of the beast don’t involve yourself at all in any coronavirus anything

starve the beast


2 posted on 08/13/2021 7:28:42 AM PDT by Truthoverpower (Arizona !!!! Now the TRUMP TRAIN is getting back on TRACK ! TRUTH! FREEDOM ! LIBERTY! )
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To: ransomnote; metmom; grey_whiskers; Cathi

Seriously?

Wait.....this is EXACTLY what Dr Lee Merritt, and other REAL doctors/scientists, have been warning about, since late last year.

This has been known, and posted about, for months.

Welcome aboard, Journal of Infection.


3 posted on 08/13/2021 7:29:59 AM PDT by Jane Long (America, Bless God....blessed be the Nation.)
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To: MMaschin

Yes, antibody-dependent Enhancement (ADE) is a very big problem with the vaccines.


4 posted on 08/13/2021 7:30:47 AM PDT by Robert DeLong
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To: Robert DeLong

If my history is correct, this public health side effect was always part of the Risk analysis when considering mass vaccinations before… I guess this time we just “knew better”


5 posted on 08/13/2021 7:32:06 AM PDT by ConservativeDude
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To: MMaschin

Bkmrk


6 posted on 08/13/2021 7:32:19 AM PDT by RushIsMyTeddyBear (RIP my "teddy bear". )
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To: MMaschin

Keep ignoring natural immunity——


7 posted on 08/13/2021 7:36:23 AM PDT by mikelets456
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To: ConservativeDude

Either that or it was intentional to make our natural immune systems less effective. I’ll let you decide which might be the real reason. 🙂


8 posted on 08/13/2021 7:58:30 AM PDT by Robert DeLong
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To: MMaschin

The jabs that are being pushed in a frenzy are slowly becoming obsolete.


9 posted on 08/13/2021 7:59:23 AM PDT by shanover (...To disarm the people is the best and most effectual way to enslave them.-S.Adams)
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To: shanover
The jabs that are being pushed in a frenzy are slowly becoming obsolete.

Yup, got to use up the supply. Meanwhile:

Step right up ladies and gentlemen, I have this new elixir right off the boat, guaranteed to solve all virus problems, for now. Just a mere few hundred billion plus immunity from product liability and you can have it. Yes siree, come one come all.

10 posted on 08/13/2021 8:03:51 AM PDT by Mouton (The enemy of the people is the media )
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To: shanover
The jabs that are being pushed in a frenzy are slowly quickly becoming obsolete.

One of the latest Israeli studies showed that the Pfizer lost 20% of its effectiveness in just two weeks in the middle of July.

11 posted on 08/13/2021 8:05:55 AM PDT by fireman15
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To: shanover

Multiple studies from numerous sources now show that the Pfizer which was the most effective is now around 40% effective and dropping fast.


12 posted on 08/13/2021 8:07:31 AM PDT by fireman15
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To: MMaschin

I do not advocate the following but thought it was interesting. Looking more into it in case I get COVID and start to decline

https://www.hindawi.com/journals/ecam/2021/5592042/
Hydrogen Peroxide as an Adjuvant Therapy for COVID-19: A Case Series of Patients and Caregivers in the Mexico City Metropolitan Area


13 posted on 08/13/2021 8:11:44 AM PDT by RummyChick (R.I.P. https://freerepublic.com/focus/f-chat/3974843/posts?q=1&;page=1)
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To: Truthoverpower

I’m starting to question is there really a “Delta Variant?” Or is this surge the same old Covid19 and term “Delta Variant” is CDC code (confession?) for ineffective vaccine?

The media/BigTech/government complex has gone full “cry wolf” IMHO... I can’t believe a single thing the say... especially when even questioning, much less dissenting voices (even doctors and U.S. Senators) are censored and silenced! #Feudalism


14 posted on 08/13/2021 8:12:35 AM PDT by FiddlePig (The greatest threat to our sacred liberty is to not value it!””)
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To: Truthoverpower

Are you worried about getting polio or smallpox? No? I wonder why. These diseases were eliminated due to vaccines. As someone who lived through the polio era I can guarantee you that there are plenty of people alive today who would not be if it weren’t for vaccines. Go peddle you bullshit to people without the ability to think critically


15 posted on 08/13/2021 8:28:45 AM PDT by from occupied ga (Your government is your most dangerous enemy - EVs a solution for which there is no problem)
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To: MMaschin
I read the abstract (summary) in the original article, and the science was way beyond me, but I came away with the impression that the current vaccines are either ineffective or contra-indicated for the recent strains (Delta et al) that have emerged, and that the authors recommend the development of new vaccines which avoid the negative biological changes (ADE) they are seeing in the original vaccines.

One thing that is still not clear to me is exactly what the dangers of ADE are.
16 posted on 08/13/2021 8:35:51 AM PDT by Steve_Seattle
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To: from occupied ga

Did it ever occur to you that not all vaccines are the same? Widely used drugs have been pulled from the market before - why can’t it happen again? And are you calling this scientific article - published in a legitimate journal of medicine - BS? Do you know more about this topic than the authors?


17 posted on 08/13/2021 8:38:34 AM PDT by Steve_Seattle
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To: Steve_Seattle; MMaschin

Here’s a summary of what it’s trying to say....

https://www.journalofinfection.com/article/S0163-4453(21)00392-3/fulltext#%20

**Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination ?**

FROM THE PAPER:

Highlights:

• Infection-enhancing antibodies have been detected in symptomatic Covid-19

• Antibody dependent enhancement (ADE) is a potential concern for vaccines

• Enhancing antibodies recognize both the Wuhan strain and Delta variants

• ADE of Delta variants is a potential risk for current vaccines

• Vaccine formulations lacking ADE epitope are suggested.


**NOTE ABOUT ADE ( ANTIBODY DEPENDENT ENHANCEMENT )**

Sometimes, after developing antibodies to a disease, our immune system can overreact the next time it gets exposed to the disease. This is a very rare phenomenon called antibody-dependent enhancement (ADE).

The antibodies involved in ADE don’t help the body’s immune response, but instead might even make things worse. ADE increases the chance that a person will develop severe symptoms of a disease when they are infected.

Antibodies that lead to ADE work like a “Trojan horse” by letting the virus into the cells and making the immune response overactive. They allow the virus to attach to our cells, causing inflammation and an enhanced immune system response.

So far, according to vaccine supporters, there have been no verified reports of ADE occurring as a result of COVID-19 vaccines.


18 posted on 08/13/2021 8:43:54 AM PDT by SeekAndFind
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To: SeekAndFind

I gather then that this is a separate claim from that of those who think the vaccines could cause changes to cellular structure that could eventually lead to clotting and other harmful effects.


19 posted on 08/13/2021 9:15:13 AM PDT by Steve_Seattle
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To: Steve_Seattle
Did it ever occur to you to read the post I was responding to? Here let me quote it to you
The vaccine industry is pure evil and fraudulent

Every single white coat lab bull crap they come up with about antibodies and immunity is completing other nonsense

The moron who posted this did not specify, but gave a blanket statement that the vaccine industry is pure evil - his words not mine, and this blanket statement is bullsh.. and your defense of it shows that either you didn't really read both posts or you agree with the original poster's blanket condemnation of the vaccine industry.
20 posted on 08/13/2021 9:30:51 AM PDT by from occupied ga (Your government is your most dangerous enemy - EVs a solution for which there is no problem)
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