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AstraZeneca to seek U.S. authorization for COVID-19 vaccine this month or early next
Nasdaq.com ^ | MAR 12, 2021 | Julie Steenhuysen (Reuters)

Posted on 03/18/2021 10:58:51 AM PDT by BeauBo

AstraZeneca Plc AZN.L is preparing to file for U.S. emergency use authorization (EUA) for its COVID-19 vaccine later this month or early April after accumulating enough data to judge the inoculation's efficacy, sources with knowledge of the ongoing clinical trial told Reuters on Friday (12 Mar).

AstraZeneca said in February it expects its vaccine could receive U.S. emergency use authorization at the beginning of April and could immediately deliver 30 million doses to locations around the United States.

(Excerpt) Read more at nasdaq.com ...


TOPICS: Business/Economy; Culture/Society; Government; News/Current Events
KEYWORDS: astrazeneca; covid
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To: BeauBo

“However, she said the agency “still cannot rule out definitively a link” between certain rare types of blood clots and the vaccine. The EMA recommended adding a description of these cases to the vaccine leaflets.” New York Post

“Experts from the EMA said the vaccine “may be associated with” highly rare blood clots, which include 18 incidents of a rare brain clot known as ... Washington Post

“Norwegian experts say deadly blood clots were caused by the AstraZeneca covid vaccine”

“Our theory that this is a powerful immune response most likely triggered by the vaccine, has been confirmed”, says professor and chief physician Pål Andre Holme. Three Norwegian health workers under the age of 50 have been hospitalized. One is dead.” Science Norway


41 posted on 03/18/2021 5:35:50 PM PDT by Cathi
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To: Whenifhow; null and void; aragorn; EnigmaticAnomaly; kalee; Kale; AZ .44 MAG; Baynative; bgill; ...

That is the very last vax I would take...


42 posted on 03/18/2021 6:08:32 PM PDT by bitt (America is the Home of the Brave, not the regime of the silenced.)
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To: BozoTexino
I’ve had a pretty good life and I’ll continue to do so as long as God wants me to. And I’ll do it without a Covid ‘vaccine.’

I figure if I died from Covid I'd rather have it be because I was denied FDA Approved HCQ and Ivermectin by vaccine sales people, instead of being from social pressure to shorten my life or quality of life with their vaccines.

43 posted on 03/18/2021 6:11:59 PM PDT by ransomnote (IN GOD WE TRUST)
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To: Cathi

One poster mentioned that the dozen or so cases of blood clotting were overwhelmingly women of childbearing age, and that blood clotting was also a known side effect of birth control pills.


44 posted on 03/18/2021 6:20:36 PM PDT by BeauBo
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To: BeauBo

This is the Phase 3 trial, right now.


45 posted on 03/18/2021 6:22:13 PM PDT by Captain Peter Blood (https://www.freerepublic.com/focus/bloggers/3804407/posts?q=1&;page)
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To: DugwayDuke

It’s down the road you need to be careful about.


46 posted on 03/18/2021 6:23:07 PM PDT by Captain Peter Blood (https://www.freerepublic.com/focus/bloggers/3804407/posts?q=1&;page)
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To: DugwayDuke
Wife and I received our second Pfizer dose this AM. So far, nothing has fallen off or no new extremities.

So you dont have a third eye growing on your forehead. Thanks.
I received my 1rst Pfizer dose yesterday, arm soreness, but other than that fine. I do worry. Thanks for the update.

47 posted on 03/18/2021 6:27:14 PM PDT by Aaron0617
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To: Cathi

This is true of any vaccine. The elderly do not have as robust an in immune system


48 posted on 03/18/2021 6:32:01 PM PDT by Mom MD
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To: Republican Wildcat

Tell a lie often enough and some will believe it


49 posted on 03/18/2021 6:34:12 PM PDT by Mom MD
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To: kaktuskid
No drug is side-effect free

That also applies to frankenfood.


50 posted on 03/18/2021 6:47:56 PM PDT by Reeses (A journey of a thousand miles begins with a government pat down.)
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To: traderrob6; DugwayDuke
"So far, nothing has fallen off or no new extremities.”


"I feel fine...really"

51 posted on 03/18/2021 7:34:40 PM PDT by Redcitizen
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To: Slyfox

No, of course not. Clotting is one of the main factors in Covid morbidity. Yesterday’s announcement simply confirmed that no causal relationship could be established between the AZ vaccine and the clotting incidents which provoked the temporary pause. In other words that that number of cases would not have been statistically abnormal in a population that size if there had been no vaccination.


52 posted on 03/19/2021 12:52:21 AM PDT by Winniesboy
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To: Captain Peter Blood

The AZ vaccine ad a full Phase III trial before authorisation and release.


53 posted on 03/19/2021 12:53:37 AM PDT by Winniesboy
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To: catnipman

No longer. See post 23 above.


54 posted on 03/19/2021 12:56:49 AM PDT by Winniesboy
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To: bitt

Novavax : ( none DNA/mRNA based)

****************

Read up:

Like most of the Covid-19 vaccine candidates, the Novavax candidate requires two shots spaced three weeks apart. But candidate NVX-CoV2373 actually works differently than the other vaccines that have made it this far. It’s a protein subunit vaccine, which means that it uses a lab-made version of the SARS-CoV-2 spike protein. This spike protein alone can’t make anyone sick. But to make sure that the body still generates the protective antibodies against it, Novavax has inserted an ingredient called an adjuvant, which acts as a hypeman for the immune system to signal it to spring into action.

Novavax’s subunit vaccine approach is a tried and true method for generating effective vaccines. Modern flu vaccines, HPV vaccines, and HepB vaccines all use a similar approach. But because these vaccines have multiple components—the spike protein and the adjuvant—they typically take longer to make than other vaccine types. That makes it surprising that 20-year-old Novavax, which has never produced a vaccine that’s reached the public before, made it to late-stage clinical trials so quickly.

According to Science Magazine, Novavax will need to rely mostly on manufacturing contracts to reach its vaccine distribution goals, but here too subunit vaccines offer an advantage. They only need to be refrigerated, not deep-frozen, and they can be made using existing equipment (in this case, bioreactors containing genetically-modified moth cells). If Novavax’s candidate is effective, those factors could make easier to produce worldwide and suited to serving lower-income countries. Already, the Serum Institute of India has agreed to partner with Novavax to manufacture vaccines and help build additional plants to do so.

The other four vaccines that have reached phase 3 trials or beyond use newer technology, which seems to work but may be harder to manufacture and distribute. The BioNTech/Pfizer and Moderna vaccines employ messenger RNA, which takes a page from our body’s own genetic decoding book to teach our cells to produce the spike protein of the SARS-CoV-2 virus. Both of these require freezing—and even super-freezing—for distribution.

https://qz.com/1950365/what-is-the-novavax-vaccine-and-how-does-it-work/


55 posted on 03/19/2021 4:22:39 AM PDT by Candor7 ((Obama Fascism:http://www.americanthinker.com/2009/05/barack_obama_the_quintessentia_1.html) )
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To: Reeses

I’ll take two of those hot cakes.


56 posted on 03/19/2021 4:23:43 AM PDT by Candor7 ((Obama Fascism:http://www.americanthinker.com/2009/05/barack_obama_the_quintessentia_1.html) )
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To: Winniesboy

I would like to know why people are getting the covid shot if they have already had the disease, when they already have confirmed immunity.


57 posted on 03/19/2021 9:56:12 AM PDT by Slyfox (Not my circus, not my monkeys )
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To: Winniesboy
Moderna phase One trial will not end before 2023 and yet it's on the market. AZ or any other vaccine has not completed a normal phase 3 trial.
In reality those trials are now and you are the Guinea pigs.
58 posted on 03/19/2021 10:01:24 AM PDT by Captain Peter Blood (https://www.freerepublic.com/focus/bloggers/3804407/posts?q=1&;page)
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To: Captain Peter Blood
Depends on your definition of a 'normal' Phase 3 trial. The AZ Phase 3 included a number of different studies, conducted simultaneously. Several of these have been completed and reported in The Lancet. Others were designed as longer-term, and are continuing. (The Brazil study, for instance, concludes in March). They were all designed with the usual parameters and safeguards. The 16 million+ plus in the UK, for instance, who have already received this vaccine are emphatically not, of course, ipso facto participants in these formal studies: which is not to say, of course, that none of them will have been double-blind participants. Some undoubtedly will have been.
59 posted on 03/19/2021 12:03:51 PM PDT by Winniesboy
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