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Experimental drug could prevent and treat COVID-19, UNC researchers report
WRALTV ^ | 2/9/21 | Mark Derewicz

Posted on 02/10/2021 12:20:20 AM PST by Freedom'sWorthIt

CHAPEL HILL – An experimental drug created at a subsidiary of Emory University has shown potential to both prevent and treat COVID-19, according to researchers at UNC-Chapel Hill.

The drug, known as EIDD-2801, is being developed by Miami-based Ridgeback Biotherapeutics. Ridgeback is partnered with drug giant Merck in the development process. The drug was invented at Drug Innovations at Emory, a not-for-profit biotechnology company wholly owned by Emory University, according to Ridgeback.

(Excerpt) Read more at wraltechwire.com ...


TOPICS:
KEYWORDS: braking; corona; covid19; drug; maybe; possibly; treatment; virus
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Possible good news.
1 posted on 02/10/2021 12:20:20 AM PST by Freedom'sWorthIt
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To: SeekAndFind

Thought you might be interested in this


2 posted on 02/10/2021 12:43:06 AM PST by Freedom'sWorthIt
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To: Freedom'sWorthIt

They prolly just gave HCQ a new name, so as to charge new drug prices and make sure Orange Man doesn’t get any credit or vindication.


3 posted on 02/10/2021 12:57:14 AM PST by Still Thinking (Freedom is NOT a loophole!)
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To: Still Thinking

Always a possibility


4 posted on 02/10/2021 1:04:17 AM PST by Freedom'sWorthIt
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To: Freedom'sWorthIt
"Prevent" sounds good.

Fauci has said it over and over...these new vaccines they're injecting do NOT prevent Covid-19.

5 posted on 02/10/2021 1:10:50 AM PST by Sacajaweau
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To: Freedom'sWorthIt

“Possible good news.”

We have great news in the case of Ivermectin and HCG.

Mexico has now adopted Ivermectin for outpatient CV19 treatment. Other countries, also. A graph of CV19 hospitalizations and deaths in Mexico city shows both rapidly decreasing since Ivermectin was introduced. India, same story. And both Ivermectin and HCQ are inexpensive.

So why do we continue to pretend that there are no treatments for CV19? Maybe because these new treatments can make a whole lot more profit for Pharma?


6 posted on 02/10/2021 1:16:45 AM PST by SecAmndmt (Aim small, miss small)
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Isotretinoin?


7 posted on 02/10/2021 1:33:34 AM PST by Gene Eric (Don't be a statist!)
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To: Freedom'sWorthIt

Similar story from yesterday in Nature.

https://www.nature.com/articles/s41586-021-03312-w

Our results show that therapeutic and prophylactic administration of EIDD-2801, an oral broad spectrum antiviral currently in phase II–III clinical trials, dramatically inhibited SARS-CoV-2 replication in vivo and thus has significant potential for the prevention and treatment of COVID-19.


8 posted on 02/10/2021 1:41:29 AM PST by tired&retired (Blessings )
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To: SecAmndmt

That and gotta keep the people scare their is no treatment, only a vax, but you can still get covid.


9 posted on 02/10/2021 1:42:02 AM PST by matt04 ( )
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To: Freedom'sWorthIt

I will find out about this as I live on Chapel Hill and use UNC for all my obscure vaccines and prophylactic treatments for world travel.

They gave me the hydroxychloroquine tablets and antibiotics that I took last January when I had Covid-19.

I took the hydroxychloroquine as a prophylactic for malaria for a several day boat trip down the Mekong River in Laos, not knowing it treated the Covid I had at the time. It wiped out the Covid almost immediately.


10 posted on 02/10/2021 1:49:45 AM PST by tired&retired (Blessings )
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To: Freedom'sWorthIt

They don’t list the ingredients


11 posted on 02/10/2021 1:52:32 AM PST by xzins (Retired US Army chaplain. Support our troops by praying for their victory. )
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To: Freedom'sWorthIt

The Safety of Molnupiravir (EIDD-2801) and Its Effect on Viral Shedding of SARS-CoV-2 (END-COVID)

https://clinicaltrials.gov/ct2/show/NCT04405739

Brief Summary:
Designed as a multi-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of EIDD-2801 on SARS-CoV-2 Virus Shedding in Newly Hospitalized Adults with polymerase chain reaction (PCR)-Confirmed COVID-19.

Detailed Description:
Phase 2a randomized, placebo-controlled, double-blinded clinical trial of EIDD-2801 in adult men and women who have tested positive for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection within 144 hours of polymerase chain reaction (PCR) confirmation and are hospitalized with a diagnosis of COVID-19. Rapid enrollment and treatment will be initiated such that the first dose of EIDD-2801 or placebo will be administered as soon as possible and within 7 days of onset of symptoms.


12 posted on 02/10/2021 1:55:13 AM PST by tired&retired (Blessings )
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To: Freedom'sWorthIt

Hedge fund manager stands to profit on ‘flip’ of taxpayer-funded coronavirus drug

Emory University’s coronavirus pill EIDD-2801 highlights financial speculation on drugs developed with public investment

https://www.washingtonpost.com/business/2020/06/11/coronavirus-drug-ridgeback-biotherapeutics/

June 25, 2020 at 11:26 a.m. EDT

Ridgeback Biotherapeutics had no laboratories, no manufacturing facility of its own and a minimal track record when it struck a deal in March with Emory University to license an experimental coronavirus pill invented by university researchers with $16 million in grants from U.S. taxpayers.

But what the tiny Miami company did have was a growing team with experience in pharmaceutical development and research and a willingness from its wealthy owners — chief executive Wendy Holman and her husband, hedge fund manager Wayne Holman — to place a bet on the treatment in the midst of the coronavirus pandemic. That wager paid off with extraordinary speed in May when, just two months after acquiring the antiviral therapy called EIDD-2801 from Emory, Ridgeback sold exclusive worldwide rights to drug giant Merck.

Ridgeback, which has one other drug in development for Ebola, was a relatively obscure entity when it snapped up EIDD-2801 from Emory in a deal signed March 19. The university, without disclosing terms, said in a news release that Ridgeback “will be responsible for conducting the necessary trials to bring EIDD-2801 to licensure.”

Within days of securing Emory’s licensing deal, the company mounted a campaign to win hundreds of millions in government funding to develop the drug, according to a whistleblower complaint by Rick Bright, former director of the Biomedical Advanced Research and Development Authority, as well as emails obtained by The Washington Post. After failing to secure the government contracts, Ridgeback launched a human safety trial of the drug in the United Kingdom and transferred rights to Merck in late May.

“I would think that universities … would not normally transfer products to basically a house-flipper,” said Aaron S. Kesselheim, a physician at Brigham and Women’s Hospital in Boston and professor at Harvard Medical School. “I wouldn’t think they would have to engage with speculators, like it appears that Ridgeback Biotherapeutics is.”

Wayne Holman, who holds a medical degree from New York University, is a hedge-fund manager with a long track record of investing in pharmaceutical stocks. He founded his fund Ridgeback Capital Management in 2006. Wendy Holman, chief executive of Ridgeback Biotherapeutics, is a former investment manager who was named to President Trump’s advisory council on HIV/AIDS in 2019.

Emory had secured pledges of $30 million in government contracts from science and defense agencies in the past five years to develop EIDD-2801 but tapped just more than half of the available funds, an Emory spokeswoman said. The university did not respond to questions about how it picked Ridgeback.

“Emory is proud that we invented EIDD-2801, and we appreciate the partnerships and government support that makes it possible to provide therapies that will benefit society,” Nancy Seideman, Emory’s vice president for academic communications, said in an email. “Any royalties that we receive — if anything — are channeled directly back to serving our educational and scientific mission.”

In instances where taxpayer-financed drugs make it to market via exclusive licensing deals — which typically have undisclosed terms — debates have sprouted around monopoly pricing.


13 posted on 02/10/2021 2:12:17 AM PST by tired&retired (Blessings )
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To: Freedom'sWorthIt

UNC is infamous for its work done on SARS bat viruses, even getting special permission to continue its research despite the general moratorium on such research that moved some of this to Wuhan. Ralph Baric is the researcer heading up this lab at UNC for decades:

https://www.nature.com/news/engineered-bat-virus-stirs-debate-over-risky-research-1.18787
https://www.newsobserver.com/news/local/article241996426.html

Does anyone remember the young black female research PhD that the NIH had working prominently with the coronavirus task force early last year? She was a recent grad from UNC who had supposedly just fortuitously been working on these viruses as part of her grad work—and why she was added to the guv’s team.


14 posted on 02/10/2021 2:24:30 AM PST by 9YearLurker
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To: Freedom'sWorthIt

Baric was also involved in the development of Remdesivir. (Which was otherwise previously developed and though very profitable doesn’t happen to work much for Covid.)

Supposedly when labs are working on bioweapons they can simultaneously, while using CRISPR to keep isolating the most virulent, gain of function, forms created, also at the same time keep isolating the least virulent variations spun out—to create the antidote that a military would also want to have for any such weapon they might want to use.


15 posted on 02/10/2021 2:28:52 AM PST by 9YearLurker
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To: Freedom'sWorthIt

What did the FDA have ivermectin renamed.....

People in the nearby County and for profit hospitals are using ivermectin for cure and suggesting for prevention. I have used ivermectin horse paste for my Lyme diseases. Week on week off


16 posted on 02/10/2021 3:41:54 AM PST by eartick (Stupidity is expecting the government that broke itself to go out and fix itself. Texan for TEXIT)
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To: eartick

“(Why) did the FDA have ivermectin renamed.....”

So they could get it to a price point more commensurate with the money available in the United States. Obviously.


17 posted on 02/10/2021 4:09:08 AM PST by BobL (TheDonald.win is now Patriots.win)
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To: Freedom'sWorthIt

Merck is MRK on the big board, yesterday traded at $75 per share, with EPS of 2.782. It’s at a six-month low, and no news about this new drug has yet been posted on e-trade. It’s too rich for my blood, but if you’ve got the money, go for it.


18 posted on 02/10/2021 4:55:45 AM PST by Eleutheria5 ("The impossible happens all the time. You just ha.782ve to believe." Will Robinson)
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To: Still Thinking

My thoughts exactly.


19 posted on 02/10/2021 5:16:07 AM PST by Rumierules
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To: Freedom'sWorthIt

and what made this breaking news? I dont see anything different from what Fauci preaches, and any of the other 1000 vaccine thread on FR the past 3 months. THis crap should be under general news, not breaking. I get it being a vaccine pimp on FR will get you so far..


20 posted on 02/10/2021 5:27:01 AM PST by max americana (FIRED LEFTARD employees at our office every election since 2008 and enjoyed seeing them cry.)
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