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Using artificial intelligence to find new uses for existing medications
Science Daily ^ | 1-4-21 | Emily Caldwell, OSU

Posted on 01/05/2021 12:44:42 PM PST by G Larry

Scientists have developed a machine-learning method that crunches massive amounts of data to help determine which existing medications could improve outcomes in diseases for which they are not prescribed.

The intent of this work is to speed up drug repurposing, which is not a new concept -- think Botox injections, first approved to treat crossed eyes and now a migraine treatment and top cosmetic strategy to reduce the appearance of wrinkles.

But getting to those new uses typically involves a mix of serendipity and time-consuming and expensive randomized clinical trials to ensure that a drug deemed effective for one disorder will be useful as a treatment for something else.

The Ohio State University researchers created a framework that combines enormous patient care-related datasets with high-powered computation to arrive at repurposed drug candidates and the estimated effects of those existing medications on a defined set of outcomes.

Though this study focused on proposed repurposing of drugs to prevent heart failure and stroke in patients with coronary artery disease, the framework is flexible -- and could be applied to most diseases.

"This work shows how artificial intelligence can be used to 'test' a drug on a patient, and speed up hypothesis generation and potentially speed up a clinical trial," said senior author Ping Zhang, assistant professor of computer science and engineering and biomedical informatics at Ohio State. "But we will never replace the physician -- drug decisions will always be made by clinicians."

(Excerpt) Read more at sciencedaily.com ...


TOPICS: News/Current Events
KEYWORDS: ai; drugs
Using AI to find new uses for existing drugs

If they didn't artificially introduce BIAS into the machine learning method, maybe they could find therapeutics to fight the China virus?

1 posted on 01/05/2021 12:44:42 PM PST by G Larry
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To: G Larry

Aside: if the goal of AI is to eventually approach human style decision making they should call it Artificial Stupidity...


2 posted on 01/05/2021 12:46:06 PM PST by Rurudyne (Standup Philosopher)
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To: G Larry

someone should notify the DoJ of this concept!! ...use AI to find uses for Existing Laws!!


3 posted on 01/05/2021 12:49:29 PM PST by sit-rep ( )
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To: G Larry

"Yes, Dave, I know that potassium cyanide has never been used to treat headaches, but you're just going to have to trust me on this one, I have a hunch..."

4 posted on 01/05/2021 12:53:06 PM PST by Boogieman
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To: G Larry

Funny how they create Artificial Intelligence but refuse to believe God created Man?

Common Sense tells us there has to be a Creator.
If not why didn’t the AI evolve on its own....


5 posted on 01/05/2021 1:03:55 PM PST by Pez149 (Time to stop saying a theory is fact....)
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To: G Larry

f they didn’t artificially introduce BIAS into the machine learning method, maybe they could find therapeutics to fight the China virus?>>>>

lIKE IVERMECTIN AND HYDROXYCHLOROQUIN

Dr. Pierre Corey pleasds with National Istitution of Health at a Hiomeland Security congressional hearing to examine Ivernectine therapy data.

https://www.reddit.com/r/CoronavirusUS/comments/k9jimk/dr_corey_pierre_pleads_to_the_nih_to_review/

Dr. Zelenko’s HCQ protocol, double blind study:

https://www.sciencedirect.com/science/article/pii/S0924857920304258


6 posted on 01/05/2021 1:15:44 PM PST by Candor7 (iT)
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To: G Larry

Right on! More drug sales! More people on drugs! Lots of drugs! No one can escape. Everyone needs to be buying more and more drugs!


7 posted on 01/05/2021 1:21:32 PM PST by Seruzawa (TANSTAAFL!)
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To: G Larry
Using Artificial Intelligence to Find New Uses for
Existing Medications

As opposed to...

Using at Least Some Intelligence to Find New Ways
to Safeguard Our Elections.

8 posted on 01/05/2021 1:28:38 PM PST by DoughtyOne (Buzzards circling over six states. Leftists looking more like dead game every day.)
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To: G Larry; timestax; Grampa Dave; musicman; Fiddlstix
[think Botox injections]


9 posted on 01/05/2021 1:31:36 PM PST by SaveFerris (Luke 17:28 ... as it was in the days of Lot; they did eat, they drank, they bought, they sold ......)
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To: G Larry; timestax; Grampa Dave; musicman; Fiddlstix
[think Botox injections]


10 posted on 01/05/2021 1:31:36 PM PST by SaveFerris (Luke 17:28 ... as it was in the days of Lot; they did eat, they drank, they bought, they sold ......)
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To: Rurudyne; dfwgator; null and void

[Aside: if the goal of AI is to eventually approach human style decision making they should call it Artificial Stupidity...]

[… In the year 3535
Ain’t gonna need to tell the truth, tell no lies
Everything you think, do, and say
Is in the pill you took today… ]

https://www.youtube.com/watch?v=izQB2-Kmiic

[you’ll pick your son,
pick your daughter too.
From the bottom of a long glass tube]


11 posted on 01/05/2021 1:40:12 PM PST by SaveFerris (Luke 17:28 ... as it was in the days of Lot; they did eat, they drank, they bought, they sold ......)
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In the year 5555
Your arms are hanging limp at your sides
Your legs got nothing to do
Some machine is doing that for you


12 posted on 01/05/2021 1:41:26 PM PST by SaveFerris (Luke 17:28 ... as it was in the days of Lot; they did eat, they drank, they bought, they sold ......)
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To: SaveFerris

I don’t like the term “artificial intelligence” That makes me think of hthe guberment people thinking they are intelligent because someone voted for them.


13 posted on 01/05/2021 2:31:15 PM PST by oldasrocks
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To: oldasrocks

Open the pod bay doors Hal

I’m sorry Dave

I can’t do that


14 posted on 01/05/2021 3:12:26 PM PST by SaveFerris (Luke 17:28 ... as it was in the days of Lot; they did eat, they drank, they bought, they sold ......)
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