Posted on 03/28/2020 8:02:13 AM PDT by PresidentFelon
I'm sure this is not such a terribly unique idea, but it seems to me we don't really need a randomized double-blind clinical trial on the drug when we know about 2 million people are prescribed hydroxychloroquine.
How hard would it be for the government to ask rheumatologists to contact their patients prescribed hydroxychloroquine to find out how many of them have tested positive for the SARS-CoV-2 virus?
While the total number of people that have acquired this disease related to the population of the United States is probably somewhat insignificant, the absence of cases among hydroxychloroquine users in areas with higher infection rates such as urban centers, hotspots and among frontline healthcare professionals should give us a pretty damn good indication whether or not the drug could be considered a prophylactic.
The implications of that finding would be huge since we would now know how to effectively control the spread of the virus for the most part and buy time to develop, manufacturer and distribute a vaccine so we could all go back to work and, hopefully, save what's left of the economy.
Please pardon the vanity and...what say you?
It's not a vaccine. We don't have enough Hydroxychloroquine for everyone to eat it like candy, and you know human nature. You might get COVID-19 anyway, just not as severely.
If you take insulin every day, does that mean you'll never get diabetes? No. But people with diabetes NEED insulin. Remember the TP shortage?
sorry...no logic allowed. You are directed to a re-education camp.
I noticed that Dr. Zev Zevlenko's Hydroxychloroquine regimen calls for one 200mg HCQ twice a day (400 mg total),plus the Z-pack and zinc. I think that's also the typical dosage Plaquenil that rheumatoid arthritis patients take.
I have R.A. and it's what I took every day for 15 years. And by the way, I had by blood and urine drawn quarterly to monitor my levels, and my eyes checked annually to screen for retinopathy, and never had the least problem. I'm not on it anymore, but I still have my last few pills sitting on the counter.
I can't imagine it would do much harm for a course of just 5 days, which is what Dr. Zev is doing.
So yeah, it's a good idea. Check those R.A. and Lupus people, and see if the Plaquenil has protected them from COVID-19.
Thank you but I’m not sure that you would require a zinc supplement to have enough in your system to effectively ward off the virus. I guess you would need to talk to a cellular biologist to determine what level of whole-body profusion and intercellular zinc is required to prevent a virus from replicating.
I also suppose that a rheumatologist could provide a questionnaire for his customers to evaluate the nature of their diet over a certain period of time to determine if they are ingesting a zinc-rich diet and then assign a probability rating of success based on that factor.
Examples of foods high in zinc include:
oysters, 3 ounces (oz): 74 mg.
beef patty, 3 oz: 5.3 mg.
Alaska king crab, 3 oz: 6.5 mg.
fortified breakfast cereal, 3/4 cup serving: 3.8 mg.
cooked lobster, 3 oz: 3.4 mg.
cooked pork chop loin, 3 oz: 2.9 mg.
baked beans, 1/2 cup serving: 2.9 mg.
dark meat chicken, 3 oz: 2.4 mg.
Jul 31, 2019
Medical News Today articles
Foods high in zinc: Benefits and list - Medical News Today
Yes, I too thought that examining that demographic would be a good indicator of the efficacy of hydroxychloroquine as a prophylactic.
Good idea.
Not an FDA double blind study means any results would be “anecdotal” [S].
My daughter is currently experiencing a multiple years long remission of her disease.
All of this is prelude to stating that the MSMs hand-wringing about a shortage of hydroxychloroquine for Lupus patients is completely contrived. I saw MSN articles attempting to denigrate the Presidents comments claiming that a months supply of hydroxychloroquine retailed for $424. Nothing could be further from the truth. Its about $20 before any insurance copays. The few SLE patients who are taking hydroxychloroquine could easily be accommodated with supplies available. This is a drug that is not only easily synthesized, it is available in generic brands. Its been around for decades... Hell, its base chemical in undiluted, unpurified form is used a cleaning compound!
In other words, the drug could be made in large quantities cheaply and fast. As for unproven, its been used successfully in the past as both a treatment and prophylactic against other forms of corona virus diseases and flu virus diseases when used in concert with other antibiotic agents; President Trump did NOT pull this information out of the Internet but actually received it from his medical advisors based on empirical results where it was working in the wild against Novel Corona Virus-19, although not under a double or triple-blind scientific study (which we obviously do not have time to do properly).
I also suppose that a rheumatologist could provide a questionnaire for his customers to evaluate the nature of their diet...
Yes, and if they take a zinc supplement. I think someone needs to get on this asap. Let's see the data.
IT’S A LUPUS TREATMENT, as is Plaquenil.
Zinc, L-lysine which destroys the virus lipid coating, Vitamin C, there are a host of herbals that help. Grapefruit Seed Extract, (GSE), which is an herbal for respiratory problems, anti-biotic for the lungs obviously. Garlic, selenium, HBT, which also destroys the lipid coating. Turmeric, gingko, ginseng, ginger which all support the immune system.
For a twenty year old, I do not look a day over 74. :-P
Gunner
Stay safe, stay well,
They don’t know how this medicine works.
What if it works by reducing the effects of the virus until the body has time to clear the virus.
If so then patients who are already taking the medicine may still test positive for the virus.
Very; interesting!!
FR_addict wrote:
“Also, I heard one doctor say that there are a lot more of the very sick coronavirus patients who have diabetes or pre-diabetes, a lot more than for ordinary flu.
The Chinese have an explosion of diabetes in their aging population that their government has been concerned would overwhelm their health system.
It turns out, hydroxycloroquine reduces risk of diabetes and also lowers glucose levels.
Hydroxychloroquine and Risk of Diabetes in Patients With Rheumatoid Arthritis
Among patients with rheumatoid arthritis, use of hydroxychloroquine is associated with a reduced risk of diabetes.
https://jamanetwork.com/journals/jama/fullarticle/207908
The effect of hydroxychloroquine on glucose control and ... www.ncbi.nlm.nih.gov articles PMC5025914
by F Sheikhbahaie -
In conclusion, hydroxychloroquine can effectively lower glucose levels through increase insulin level. ...
Treatment with hydroxychloroquine can be employed as a therapeutic in patients with prediabetic states who are at risk of developing diabetes mellitus.”
Lots of flu epidemics over the past 15 years.
Did you ever get it?
Other virus based diseases?
Good idea for a quicker proof of the concept of pre-exposure prophylaxis. However most of those patients probably take 1-2 200mg tablets daily which may well be overkill and may limit scaling up prophylaxis while supplies are limited. A better question, perhaps more easily answered outside US, is whether those already on the drug at malaria prophylaxis dosage 2 pills a weekare protected. Supplies could go further and that dose has a huge safety record. India is now suggestIng that dose for prophylaxis of exposed family members or healthcare workers, but I dont know if they, or anyone else, have or is collecting appropriate data on its efficacy. I havent seen any trials listed for that dose. There should be some. If you can prove whether it works, easy and quick in the NYC outbreak, it could stand in for the vaccine until thats available IF they can make enough drug.
I think I don't much get viral infections ----
BUT they're so similar to bacterial, symptom-wise, plus sometimes people get a one-two punch (virus sets you up for bacterial) that it's hard for me to tell.
I cannot guarantee the accuracy of these self-assessments.
Obviously an honest answer.
Thanks.
Yes, and and it is used to treats rheumatoid arthritis as well as a couple other autoimmune diseases also.
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