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Five disorders from depression to autism share a genetic link, which could pave the way for new...
Daily Mail (UK) ^ | 28 February 2013 | CLAIRE BATES

Posted on 02/28/2013 5:16:22 PM PST by neverdem

Five disorders from depression to autism share a genetic link, which could pave the way for new treatments

Autism, ADHD, bipolar disorder, depression and schizophrenia overlap at a genetic level

Two gene markers common to all of the disorders govern the balance of calcium in brain cells

New understanding could help develop treatments

The five most common mental health and developmental disorders share a common genetic root, a study has found. Scientists found a link between autism, attention deficit hyperactivity disorder (ADHD), bipolar disorder, depression and schizophrenia.

The findings, from Massachusetts General Hospital in Boston, could revolutionise how doctors think about the conditions.

'We have been able to discover specific genetic variants that seem to overlap among disorders that we think of as very clinically different,' study leader Dr Jordan Smoller told NBC News.

The team found four genetic variants were associated with all five conditions. These markers were more common in people with the one of the disorders compared to healthy people.

In particular, the research highlighted mutations in two genes that help govern the balance of calcium in brain cells. One of the roles calcium plays is in communication between cells.

The discovery could lead scientists to reclassify the conditions and pave the way to new treatments, say the researchers writing in the The Lancet medical journal. Scientists scanned the genome, or genetic code, of more than 33,000 patients with mental disorders as well as 27,888 healthy individuals. The study was the largest investigation of genetic links to psychiatric illness ever conducted. While the five conditions have always been thought of as separate they do share some symptoms. For instance, mood and thinking problems can occur with schizophrenia, bipolar disorder and depression. And children with ADHD often have symptoms of other developmental disorders, such as autism.

While the...

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: adhd; autism; bipolardisorder; depression; genetics; schizophrenia
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

It's a FReebie if you're registered.

1 posted on 02/28/2013 5:16:35 PM PST by neverdem
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To: Incorrigible

Ping


2 posted on 02/28/2013 5:19:24 PM PST by neverdem ( Xin loi min oi)
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To: neverdem

Genetic problem? I can make that disappear ...

3 posted on 02/28/2013 5:22:32 PM PST by ClearCase_guy (Nothing will change until after the war.)
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To: ClearCase_guy

EXACTLY!! this is all about population control and dare I say it?
Agenda 21.

Perhaps they should really reveal how we have been slowly poisoned since the fifties, fluoride, vaccines, GMO’s etc. Of course it is genetic NOW.


4 posted on 02/28/2013 5:28:43 PM PST by acapesket
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To: acapesket

Ummm....you do know that there was mental illness before 1950, right?


5 posted on 02/28/2013 5:30:44 PM PST by Strategerist
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To: Strategerist
Now everybody and their brother has some kind of mental "illness"...mind drugs being doled out like never before.

Something definitely wrong with the current landscape.

6 posted on 02/28/2013 5:41:40 PM PST by what's up
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To: Strategerist

Umm yes I do. However with the plethora of new diseases that have happened since the late 40’s/50’s. Fibromyalgia, CFS, Lyme disease, the increase in Alzheimer’s and ALS ( both have run in the genetic pool) I believe that as my favorite GP of 50 years claimed years ago... “when they started making plastics and screwing around with food, I knew that there would be BIG problems”.

Happy High Fructose corn syrup to you and oh by the way, they are treating your cold cuts with silicone to allegedly prevent lysteria. God did not intend for your body to ingest these substances, but feel free to go on eating them.

Love Conservatism but believe that at our core, we need to go back to the basics.

Sorry that we disagree.


7 posted on 02/28/2013 5:50:31 PM PST by acapesket
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To: acapesket

Who uses sugar in any form or cold cuts? Geez!


8 posted on 02/28/2013 6:13:54 PM PST by spel_grammer_an_punct_polise (Learn three chords and you, too, can be a Rock Star!)
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To: neverdem

genetic links to 5 mental disorders


9 posted on 02/28/2013 7:08:22 PM PST by quintr
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To: AdmSmith; AnonymousConservative; Berosus; bigheadfred; Bockscar; ColdOne; Convert from ECUSA; ...

I would have remembered to take my antidepressants, but I was too busy memorizing the license plates of the cars that rolled past my house. Thanks neverdem.


10 posted on 02/28/2013 7:20:52 PM PST by SunkenCiv (Romney would have been worse, if you're a dumb ass.)
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To: neverdem

11 posted on 02/28/2013 7:28:03 PM PST by JoeProBono (A closed mouth gathers no feet - Mater tua caligas exercitus gerit ;-{)
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To: what's up

Sorry if this sounds like a conspiracy theory, but, if they can find a genetic link to mental illness then maybe they can use that excuse to further their anti-gun agenda. “You have the genetic marker for schizophrenia in your blood, so no gun for you!”


12 posted on 02/28/2013 7:41:45 PM PST by k4gypsyrose
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To: neverdem

So I should take more calcium?


13 posted on 03/02/2013 1:26:23 PM PST by rmlew ("Mosques are our barracks, minarets our bayonets, domes our helmets, the believers our soldiers.")
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To: rmlew
So I should take more calcium?

Maybe more magnesium or a calcium channel blocker or avoid the latter like the plague?

14 posted on 03/02/2013 10:57:18 PM PST by neverdem ( Xin loi min oi)
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To: SunkenCiv

Oh look, a chicken!


15 posted on 03/02/2013 11:32:13 PM PST by patton (Tinker toys, watches, and shiny things - we all sell rocks for a living.)
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To: patton

Maybe Pareidolia is rooted in the same genes.


16 posted on 03/03/2013 8:09:38 AM PST by SunkenCiv (Romney would have been worse, if you're a dumb ass.)
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To: SunkenCiv

Hey, just because I see patterns others miss, does not mean I am apophenic.


17 posted on 03/03/2013 3:52:39 PM PST by patton (Tinker toys, watches, and shiny things - we all sell rocks for a living.)
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To: acapesket; Strategerist

http://news.unchealthcare.org/news/2013/april/international-study-confirms-multiple-genes-contribute-to-schizophrenia-risk ~ bringing you all up todate, it’s in our genes. That meant it was in there long before plastics or silicon cookware!


18 posted on 04/21/2013 4:12:11 PM PDT by muawiyah
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To: k4gypsyrose

you need to know that ~ http://news.unchealthcare.org/news/2013/april/international-study-confirms-multiple-genes-contribute-to-schizophrenia-risk ~ we are THAT CLOSE to such a test. Fur Shur Lanza’s mother would have never let him take that test.


19 posted on 04/21/2013 4:13:37 PM PDT by muawiyah
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To: neverdem

http://news.unchealthcare.org/news/2013/april/international-study-confirms-multiple-genes-contribute-to-schizophrenia-risk ~ this one too ~ the stuff is just rolling out of there. The connections to the genes are being found by matching tens of thousands of genomes of people diagnosed WITH or WITHOUT schizophrenia ~ we couldn’t have done this 10 years back ~ now we can and this horrible condition is one of the first to be studied this way. now for an effective treatment.


20 posted on 04/21/2013 4:15:50 PM PDT by muawiyah
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