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Bacteria-immune system 'fight' can lead to chronic diseases, study suggests
Biology News Net ^ | August 2, 2012 | NA

Posted on 08/04/2012 7:16:59 PM PDT by neverdem

Results from a study conducted at Georgia State University suggest that a "fight" between bacteria normally living in the intestines and the immune system, kicked off by another type of bacteria, may be linked to two types of chronic disease.

The study suggests that the "fight" continues after the instigator bacteria have been cleared by the body, according to Andrew Gewirtz, professor of biology at the GSU Center for Inflammation, Immunity and Infection. That fight can result in metabolic syndrome, an important factor in obesity, or inflammatory bowel disease (IBD).

The results were published in the journal Cell Host & Microbe.

"The implication at present is that it is very important to control the early environment," Gewirtz said. "We need to examine how this can be achieved – perhaps via breastfeeding, a more diverse diet, probiotics are possibilities."

The study's results are important as instances of chronic diseases like metabolic syndrome and IBD are increasing rapidly among humans, he explained.

Metabolic syndrome involves risk factors, including obesity, which can lead to cardiovascular disease, diabetes and stroke. According to the American Heart Association, about 35 percent of adults are affected by this syndrome.

IBD, which includes Crohn's disease and ulcerative colitis, happens when the intestines become inflamed, leading to abdominal cramps and pain, diarrhea, weight loss and bleeding.

More than 600,000 Americans annually have some kind of inflammatory bowel disease, according to the American Academy of Family Physicians.

Bacteria normally live in the gut of humans, with the average human having about 4 pounds of bacteria living there.

"It is increasingly apparent that bacteria are playing a role in healthy development, and need to be properly managed by the mucosal immune system to avoid inflammatory diseases" Gewirtz explained. Source : Georgia State University


TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: bacteria; health; healthmedicine; immunesystem; immunology; intestines; medicine; microbiology
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Transient Inability to Manage Proteobacteria Promotes Chronic Gut Inflammation in TLR5-Deficient Mice
1 posted on 08/04/2012 7:17:08 PM PDT by neverdem
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To: neverdem

It is also a matter of scientific fact that both Obama and Romney and detrimental to good digestion in conservatives. Both are known to induce explosive bowel movements and projectile vomiting in the conservative population studied.


2 posted on 08/04/2012 7:26:29 PM PDT by Sola Veritas (Trying to speak truth - not always with the best grammar or spelling)
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To: neverdem

See what you get for posting an interesting article?


3 posted on 08/04/2012 7:36:34 PM PDT by chessplayer
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To: neverdem

Ping for later


4 posted on 08/04/2012 7:49:29 PM PDT by Vinnie (A)
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To: neverdem

Makes sense. I’ve noticed that chronic low-grade infections tend to have very similar symptoms, whether the infecting agent is a bacteria, virus, fungus, whatever. As one example, fibromyalgia has the same symptoms as both chronic Lyme’s disease, and certain types of mold exposure, to the point where they are all easily mistaken for one another. Sometimes I really wish I was a research scientist, because I’d love to pursue that lead.


5 posted on 08/04/2012 8:09:51 PM PDT by Ellendra ("It's astounding how often people mistake their own stupidity for a lack of fairness." --Thunt)
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To: Ellendra
The answer . . prayer and non colloidal SILVER SOL. . .liquid 10ppm, 22ppm, and 24ppm GEL. No one should be without it. Great for animals, too. Do a search for Dr. Pedersen. . . shop around for the best prices. Over 90 uses including Lyme's, fibromyalgia, mold, MRSA, Crohn's. Speaking from personal experience (family and friends).
6 posted on 08/04/2012 11:15:18 PM PDT by Maudeen (Proverbs 3:5-6)
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To: afnamvet

Ping


7 posted on 08/05/2012 1:01:57 AM PDT by neverdem (Xin loi minh oi)
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To: Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; Battle Axe; null and void; ...
What Makes Bat Viruses So Deadly?

FReepmail me if you want on or off my combined microbiology/immunology ping list.

8 posted on 08/05/2012 1:11:18 AM PDT by neverdem (Xin loi minh oi)
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To: neverdem
Has there been any study or studies that have established that a change in gut flora causes, rather than results from, one of those metabolic diseases?

Everything I've read so far on the subject has documented a correlation between gut flora and certain diseases, but I've yet to see any causative relationship established either way. The journal article referenced in this article isn't indexed at PubMed yet, so I can't read it. However, I question whether the response of TLR5 knockout mice to infection is relevant to the question of which comes first, the gut flora or the inflammatory condition.

9 posted on 08/05/2012 4:46:49 AM PDT by exDemMom (Now that I've finally accepted that I'm living a bad hair life, I'm more at peace with the world.)
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To: Maudeen
Details, please, especially with respect to (OK, DISrespect to, as we are trying to kill them) molds?

Cheers!

10 posted on 08/05/2012 6:52:37 AM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: grey_whiskers

I typed in silver sol and mold and found this

I’ve seen the info several other places. Check also on he right on this link for other uses for it.

http://www.silversolsolution.com/black-mold/

I don’t know what we would have done without silver sol for my elderly parents. I’d have some on hand for emergencies especially. This is NOT your usual colloidal silver! I read where a baby could ingest a whole tube of it and not be affected.


11 posted on 08/05/2012 9:26:15 AM PDT by Maudeen (Proverbs 3:5-6)
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To: Maudeen

I’ve seen too many contradictory studies on colloidal silver to put much faith in it.


12 posted on 08/05/2012 9:42:21 AM PDT by Ellendra ("It's astounding how often people mistake their own stupidity for a lack of fairness." --Thunt)
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To: neverdem
Dr. Hibbert: "So you can see you have every disease, and a few we've never really seen. They've reached a sort of symbiance and are balanced in such a way that it isn't affecting you. ha ha ha."
Mr. Burns: "So what you're saying is I'm invincible?"
Dr. Hibbert: "Oh dear God no, the slightest breeze could kill y..."
Mr. Burns: "Invincible..."


13 posted on 08/05/2012 9:54:17 AM PDT by Lancey Howard
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To: Ellendra; Maudeen

“...too many contradictory studies on colloidal silver...”

Yes, there are many contradictory studies because of the agenda of some doing studies...there is nothing contradictory about the results gleaned from using colloidal silver. Also, some of the studies have used ionic silver, not colloidal silver...big difference. Some years ago researchers, when dimes were real silver, would put a dime in a petri dish to steralize it in the lab. The many benefits of silver predate antibiotics, predate modern medicine. And bacteria, virus, mold does cannot develop a resistance to it.

A colloid is a substance of ultramicroscopic particles. Colloidal silver is nothing more than very tiny particles of pure silver suspended in distilled water through the process of electrolysis. The smaller the particles in CS the better the body can assimilate them. When current is applied to silver in solution the particles that break off will always be the same size: 1.26 angstroms (.000126 microns). This is so small that its nearest rival is an atom. Colloidal silver is odorless, tasteless and has no known negative reaction to any medication, health problem, diet, or artificial alteration to the human body. It is considered to be Creator God’s natural antibiotic provided for the good health of the people of planet Earth.

Silver has been known to be a bactericide for at least 1200 years. Even in ancient times, it was known to prevent disease, and it was said that disease could not be transmitted in drinking from a silver cup. Silver coins were commonly dropped into a jar to prevent the spoilage of milk and other drink, and silver containers were used to prolong the freshness of foods in general.

UCLA ran some tests on Colloidal Silver and their report states: “The silver solutions were antibacterial for Streptococcus pyogenes, Staphylococcus aureus, Neisseria gonorrhea, Gardnerella Vaginalis, Salmonella Typhi, and other enteric pathogens, fungicidal for Candida albicans, Candida globata, and M. furfur, and it killed every virus that was tested in the lab”.
Other voices in the medical community are saying…
Dr. Hirschberg, John Hopkins: “...remarkable for their beneficial action in infective states”.
Dr. Henry Cooks: “I know of no microbe that is not killed in laboratory tests within six minutes”.
Dr. Gary Smith: “When silver was present the cancer cell was de-differentiated and the body was restored”.

I hope, Ellendra, you do not find this info too contradictory...


14 posted on 08/05/2012 10:11:40 AM PDT by GGpaX4DumpedTea (I am a Tea Party descendant...steeped in the Constitutional Republic given to us by the Founders.)
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To: Ellendra

This is not colloidal silver. It helped my sister’s Crohn’s, my mother’s MRSA, a friend of my sister’s husband who was literally dying after infected sutures. Put the gel on and they said it looked like a volcano erupting. He also ingested the liquid. A few months later he went back to the doctor and there was absolutely NO scarring. The doctor was amazed and wondered what he did. My beagle was mauled and on his deathbed. The vets sewed him up. I decided to use the gel rather than the ointment they gave. No indication of a wound now. The vet a year later couldn’t believe it was the same dog. . . . .the stories go on and on. If stock were available, I would buy it.


15 posted on 08/05/2012 11:09:53 AM PDT by Maudeen (Proverbs 3:5-6)
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

Ping... (Thanks, neverdem!)


16 posted on 08/05/2012 11:42:15 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: exDemMom
Has there been any study or studies that have established that a change in gut flora causes, rather than results from, one of those metabolic diseases?

Everything I've read so far on the subject has documented a correlation between gut flora and certain diseases, but I've yet to see any causative relationship established either way.

It's an interesting dilemma, but it's probably unethical to test the hypothesis directly, i.e. infect naive humans with H. Pylori to see if they subsequently develop metabolic syndrome or type 2 diabetes.

I think you can test it indirectly by testing type 2 diabetics for H. Pylori antibodies and treating those who are positive for it. The National Health and Nutrition Examination Surveys found a correlation between H. Pylori antibodies and elevated hemoglobin A1c. That would be another population for treatment of a presumptive H.Pylori in a double blind trial. If that resolves type 2 diabetes or prediabetic hyperglycemia, that speaks for itself. If I had my druthers, I'd test those responding to H. pylori treatment with normal blood glucose levels for any common defects in their innate or acquired immune systems.

The journal article referenced in this article isn't indexed at PubMed yet, so I can't read it.

I found the link in comment# 1 by going to the named journal, Cell Host & Microbe. It's a method I had to use after the updated PubMed couldn't support my old computer. I usually check the author's surname on the journal's homepage and in their advance online publication or equivalent link.

However, I question whether the response of TLR5 knockout mice to infection is relevant to the question of which comes first, the gut flora or the inflammatory condition.

That's not unreasonable, but I'd like to rule out defects in the innate immune system, e.g. Toll-like receptors and diabetes: a therapeutic perspective.

Association between gastric Helicobacter pylori colonization and glycated hemoglobin levels.

Helicobacter pylori infection is associated with an increased rate of diabetes.

17 posted on 08/05/2012 12:46:21 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem

After centuries of anecdotal experience, scientists have finally figured out why common peppermint is an effective counter to many cases of IBD.

There are intestinal cells that become chronically inflamed, which creates a vicious circle keeping them inflamed. But peppermint soothes these cells which allows the system to normalize.

Just drinking a teaspoon full of natural peppermint extract added to a glass of water, once or twice a day, after a week or two is effective for many people in breaking their IBD cycle.

The scientists noted that some foods and are known to irritate these cells, like hot pepper, mustard, caffeine, acidic foods, and fruits in *some* people, as well as those that create a mild allergic response in particular people.


18 posted on 08/05/2012 1:04:19 PM PDT by yefragetuwrabrumuy
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To: Mars

bfl


19 posted on 08/05/2012 2:26:54 PM PDT by Mears
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To: neverdem

bm


20 posted on 08/05/2012 2:37:04 PM PDT by rurgan (Sunset all laws at 4 years.China is destroying U.S. ability to manufacture,makes everything)
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