Posted on 02/17/2012 8:20:56 AM PST by marthemaria
Doctors are calling for a clinical trial of an experimental drug treatment that it is claimed can reverse the symptoms of Alzheimer's disease "in minutes".
U.S. researchers say the treatment allowed an 82-year- old sufferer to recognise his wife for the first time in years.
In the UK, specialists believe the claims should be properly tested as only a few patients have been treated so far.
The treatment involves injecting a drug called Enbrel - which is normally used to treat arthritis - into the spine at the neck.
Patients are then tilted to encourage blood flow into the brain where the drug is designed to block a chemical responsible for inflammation. At least one Alzheimer's patient had his symptoms reversed "in minutes" while others have shown some continuing improvement in problems such as forgetfulness and confusion after weekly injections.
They needed less help from carers during treatment, which appears to reach a plateau at three months.
Around 50 people are being treated by the Institute of Neurological Research, a private clinic in California, with some having had injections for three years.
In one case, the clinic has video evidence of Marvin Miller, 82, which showed he was unable to answer basic questions by a nurse, or identify-everyday objects like a bracelet and a pencil.
Shortly afterwards he is injected with the drug and it is claimed that five minutes later he could greet his shocked wife, who said he had not recognised her for years.
The experiment follows the discovery that levels of TNF (tumour necrosis factor) can be up to 25 times higher in the fluid surrounding the brain in sufferers of Alzheimer's disease.
(Excerpt) Read more at dailymail.co.uk ...
Ping.
WOW! My mother-in-law and mother both have early stage Alzheimers. What a ray of hope!
This seems to be based on the hypothesis that Alzheimer’s is caused by inflammation.
There might be existing drugs that do not need to be injected into the spine that could work, too. I hope that researchers are following up on that approach.
So Enbrel inhibits TNF. Receiving injection in the neck region of the spinal canal is not a pleasant experience, but hey, if you don’t remember the pain, what is there to lose? I look forward to continued improvement of delivery systems and long-term help for these patients. The article said nothing about the frequency of dosing??
Another, DIFFERENT drug for Alzheimers, shows promise:
http://www.freerepublic.com/focus/f-chat/2847866/posts
That is good news. I hope for you and your family this is a cure. I lost my mother to Alzheimers six years ago.
Sadly, we tried Enbrel with my mother and it didn’t reverse anything.
It is possible that the conditions of the treatment have changed over the last few years, but I firmly believe that Alzheimer’s Disease is entirely subjective to the afflicted.
It’s a terrible disease and for what I know, it is genetic.
I try to live a different life than my mother. Excercise more, drink more water, eat lots of fresh coconut and cook with coconut oils (search that). I will probably inherit this or pass it on to my children.
I hope not neccessarily for a cure, but for something that will eliminate the dimentia entirley.
Being forgetful is not entirely bad, but being in the grip of confusion and terror is miserable.
Successful diabetic drugs ALSO have this characteristic ~ they turn on or off genes in the nucleus or in the mitochondria.
Successful diabetic drugs ALSO have this characteristic ~ they turn on or off genes in the nucleus or in the mitochondria.
Sadly, we tried Enbrel with my mother and it didn’t reverse anything.
It is possible that the conditions of the treatment have changed over the last few years, but I firmly believe that Alzheimer’s Disease is entirely subjective to the afflicted.
It’s a terrible disease and for what I know, it is genetic.
I try to live a different life than my mother. Excercise more, drink more water, eat lots of fresh coconut and cook with coconut oils (search that). I will probably inherit this or pass it on to my children.
I hope not neccessarily for a cure, but for something that will eliminate the dimentia entirley.
Being forgetful is not entirely bad, but being in the grip of confusion and terror is miserable.
Sadly, we tried Enbrel with my mother and it didn’t reverse anything.
It is possible that the conditions of the treatment have changed over the last few years, but I firmly believe that Alzheimer’s Disease is entirely subjective to the afflicted.
It’s a terrible disease and for what I know, it is genetic.
I try to live a different life than my mother. Excercise more, drink more water, eat lots of fresh coconut and cook with coconut oils (search that). I will probably inherit this or pass it on to my children.
I hope not neccessarily for a cure, but for something that will eliminate the dimentia entirley.
Being forgetful is not entirely bad, but being in the grip of confusion and terror is miserable.
Prayers for an early cure...
That drug, bexarotene (Eisai’s Targretin) can be taken orally.
Okay, Who’s got the Alzheimer’s Ping List?.....I forgot.............
This is amazing video that captures this man that recognizes his wife and his children for the first time in a long time.
Not funny.
Oh my..... my screen’s all blurry.
Thank you Lord, for our minds and our hearts.
Tatt
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