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Research shocker: genetically engineered viruses seek out, kill cancer
Engadget | July 20, 2010 | Laura Jane

Posted on 07/20/2010 7:49:39 AM PDT by James C. Bennett

New research at UCLA's Jonsson Comprehensive Center seeks to turn the human body into a genetically engineered cancer-killing machine. The fact that the human body doesn't see cancer as a threat to be destroyed naturally is part of what makes treating it so difficult, so this research uses a harmless, HIV-like virus as the vehicle to carry T-cells (which fight disease) to lymphocytes, and simultaneously carry a reporter gene, which show up in positron emission tomography (PET) scanning, as you can see in the photographs above. So far the researchers have injected the cells into the bloodstreams of melanoma-infected mice, and they began to see evidence of their work within two or three days, and by ten days, it was obvious that in most cases, the cells were indeed fighting the cancer. The process, they admit, could take longer in human beings, and would require about one billion tumor seeking lymphocytes per person treated. They are currently working on creating a vehicle to safely carry the lymphocytes in the human body, and expect the human trial leg of the study to begin within one year.
sourcePNA


TOPICS: Business/Economy; News/Current Events
KEYWORDS: cancer; macrophage; phage; virus
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1 posted on 07/20/2010 7:49:43 AM PDT by James C. Bennett
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To: Admin Moderator

Oops, forgot the source link:

http://www.engadget.com/2010/07/20/research-shocker-genetically-engineered-viruses-seek-out-kill/


2 posted on 07/20/2010 7:50:27 AM PDT by James C. Bennett
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To: James C. Bennett

This is welcome news.


3 posted on 07/20/2010 7:52:49 AM PDT by Juan Medén
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To: James C. Bennett
I hope this does not end up a nightmare scenario as shown in the movie -- I AM LEGEND.

4 posted on 07/20/2010 7:54:10 AM PDT by SeekAndFind
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To: Juan Medén

I think the FDA is so in bed with the chemo industry, they will just bury this.


5 posted on 07/20/2010 7:54:43 AM PDT by aimhigh
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To: James C. Bennett
" this research uses a harmless, HIV-like virus as the vehicle to carry T-cells"

Yeah. That sounds risk-free.

6 posted on 07/20/2010 7:57:19 AM PDT by TheClintons-STILLAnti-American
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To: aimhigh
I think the FDA is so in bed with the chemo industry, they will just bury this.

Let's say they do. I couldn't imagine Russia, S. Korea, Japan, Germany or Red China ignoring this if there is something there.
7 posted on 07/20/2010 7:58:15 AM PDT by Dr. Sivana (There is no salvation in politics)
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To: James C. Bennett
"harmless, HIV-like virus"

Sort of like those cute, harmless SUVs?

8 posted on 07/20/2010 7:59:36 AM PDT by Paladin2
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To: aimhigh

you got that correct.

the industry is more interested in the $$$$ reaped
from failing to cure ab initio. hence the delays
and delays, where in europe that goes to years.


9 posted on 07/20/2010 8:00:13 AM PDT by Diogenesis (Article IV - Section 4 - The United States shall protect each of them against Invasion)
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To: James C. Bennett
This sounds like a huge breakthrough, but extreme care must be taken.

"The best laid plans of mice and men oft go awry" - Robert Burns

10 posted on 07/20/2010 8:00:13 AM PDT by The Sons of Liberty (The usurper 0bama regime is a "Clear and Present Danger" to AMERICA! - Mene, Mene, Tekel, Upharsin)
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To: Dr. Sivana

Mexico, India, and Costa Rica sure as hell won’t ignore it either.


11 posted on 07/20/2010 8:00:26 AM PDT by Enterprise (As a disaster unfolds, a putz putts.)
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To: TheClintons-STILLAnti-American

If the virus is so harmless, why does it take out the cancer cells?


12 posted on 07/20/2010 8:01:57 AM PDT by Paladin2
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To: James C. Bennett

Viri have long been used in genetic modification of bacteria and somatic cells. Cancer cells have certain distint differences such as longer teleomeres and differences in cell membranes which make targeting possible. There also used extensively in bioengineering to insert plasmids into cells to add charicteristics for manufacturing purposes.


13 posted on 07/20/2010 8:05:02 AM PDT by Dayman
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To: James C. Bennett

The field of healing has been so dominated by the drug pushers/cutters for so long that often people forget that anything else is possible.


14 posted on 07/20/2010 8:08:05 AM PDT by Seruzawa (If you agree with the French raise your hand - If you are French raise both hands.)
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To: Paladin2

A virus can be modified to target very specific proteins or nucleic acids that are unique to different cell types.

Cancer cells usually become cancer cells due to a genetic mutation. Once that mutation is identified a virus can be made which targets that specific chain. In the presence of that chain it will be able to reproduce and lyse (pop) the cell. Without that mutated chain it will still infect the cell but will not be able to reproduce itself and lyse the host cell.


15 posted on 07/20/2010 8:08:17 AM PDT by Dayman
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To: James C. Bennett
Virus's mutate very quickly. The latest I Am Legend movie used this scenario to make the premise of the movie. Cool movie actually.
16 posted on 07/20/2010 8:08:49 AM PDT by Free_in_Alabama (The average citizen is to lazy to steal from you, instead they are asking the government to do it)
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To: Paladin2

It doesn’t. It’s a “vehicle” to carry the T-cells to the cancer cells..............like a Taxi cab only smaller...............


17 posted on 07/20/2010 8:08:56 AM PDT by Red Badger (No, Obama's not the Antichrist. But he does have him on speed dial...............)
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To: James C. Bennett

This is how the movie I AM LEGEND starts.


18 posted on 07/20/2010 8:09:04 AM PDT by Lazamataz ("We beat the Soviet Union. Then we became them." -- Lazamataz, 2005)
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To: Free_in_Alabama

It was a remake of the 70’s movie, Omega Man” starring Charleton Heston...............


19 posted on 07/20/2010 8:09:54 AM PDT by Red Badger (No, Obama's not the Antichrist. But he does have him on speed dial...............)
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To: SeekAndFind
Or this....
20 posted on 07/20/2010 8:10:14 AM PDT by Le Chien Rouge
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