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Researchers Say Popular Fish Contains Potentially Dangerous Fatty Acid Combination (Tilapia)
www.newswise.com ^ | 08 July 2008 | Staff

Posted on 07/08/2008 5:47:56 AM PDT by Red Badger

Farm-raised tilapia, one of the most highly consumed fish in America, has very low levels of beneficial omega-3 fatty acids and, perhaps worse, very high levels of omega-6 fatty acids. The combination could be potentially dangerous for some patients with heart disease, arthritis, asthma and other allergic and auto-immune diseases that are particularly vulnerable to an “exaggerated inflammatory response.”

Newswise — Farm-raised tilapia, one of the most highly consumed fish in America, has very low levels of beneficial omega-3 fatty acids and, perhaps worse, very high levels of omega-6 fatty acids, according to new research from Wake Forest University School of Medicine.

The researchers say the combination could be a potentially dangerous food source for some patients with heart disease, arthritis, asthma and other allergic and auto-immune diseases that are particularly vulnerable to an “exaggerated inflammatory response.” Inflammation is known to cause damage to blood vessels, the heart, lung and joint tissues, skin, and the digestive tract.

“In the United States, tilapia has shown the biggest gains in popularity among seafood, and this trend is expected to continue as consumption is projected to increase from 1.5 million tons in 2003 to 2.5 million tons by 2010,” write the Wake Forest researchers in an article published this month in the Journal of the American Dietetic Association.

They say their research revealed that farm-raised tilapia, as well as farmed catfish, “have several fatty acid characteristics that would generally be considered by the scientific community as detrimental.” Tilapia has higher levels of potentially detrimental long-chain omega-6 fatty acids than 80-percent-lean hamburger, doughnuts and even pork bacon, the article says.

“For individuals who are eating fish as a method to control inflammatory diseases such as heart disease, it is clear from these numbers that tilapia is not a good choice,” the article says. “All other nutritional content aside, the inflammatory potential of hamburger and pork bacon is lower than the average serving of farmed tilapia.”

The article notes that the health benefits of omega-3 fatty acids, known scientifically as “long-chain n-3 polyunsaturated fatty acids” (PUFAs), have been well documented. The American Heart Association now recommends that everyone eat at least two servings of fish per week, and that heart patients consume at least 1 gram a day of the two most critical omega-3 fatty acids, known as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid).

But, the article says, the recommendation by the medical community for people to eat more fish has resulted in consumption of increasing quantities of fish such as tilapia that may do more harm than good, because they contain high levels of omega-6 fatty acids, also called n-6 PUFAs, such as arachidonic acid.

“The ratio of arachidonic acid (AA) to very long-chain n-3 PUFAs (EPA and DHA) in diets of human beings appears to be an important factor that dictates the anti-inflammatory effects of fish oils,” the researchers write. They cite numerous studies, including a recent one that predicts “that changes in arachidonic acid to EPA or DHA ratios shift the balance from pro-inflammatory [agents] to protective chemical mediators … which are proposed to play a pivotal role in resolving inflammatory response” in the body.

For their study, the authors obtained a variety of fish from several sources, including seafood distributors that supply restaurants and supermarkets, two South American companies, fish farms in several countries, and supermarkets in four states. All samples were snap-frozen for preservation pending analysis, which was performed with gas chromatography.

The researchers found that farmed tilapia contained only modest amounts of omega-3 fatty acids – less than half a gram per 100 grams of fish, similar to flounder and swordfish. Farmed salmon and trout, by contrast, had nearly 3 and 4 grams, respectively.

At the same time, the tilapia had much higher amounts of omega-6 acids generally and AA specifically than both salmon and trout. Ratios of long-chain omega-6 to long-chain omega-3, AA to EPA respectively, in tilapia averaged about 11:1, compared to much less than 1:1 (indicating more EPA than AA) in both salmon and trout.

The article notes that “there is a controversy among scientists in this field as to the importance of arachidonic acid or omega-6:omega-3 ratios vs. the concentration of long-chain omega-3 alone with regard to their effects in human biology.” Those issues are raised in an editorial in the same issue of the Journal.

The Wake Forest article anticipates that criticism and notes that one human study involving AA showed a probable gene-nutrient connection to coronary heart disease in a specific group of heart disease patients. In another study, four subjects were removed after consumption of high amounts of AA due to concerns about the effect of the acid on their blood platelets.

Floyd H. “Ski” Chilton, Ph.D., professor of physiology and pharmacology and director of the Wake Forest Center for Botanical Lipids, is the senior author of the Journal article. He said that in next month’s Journal, he will publish a rebuttal to this month’s editorial.

“We have known for three decades that arachidonic acid is the substrate for all pro-inflammatory lipid mediators,” Chilton said in an interview. “The animal studies say unequivocally that if you feed arachidonic acid, the animals show signs of inflammation and get sick.

“A New England Journal of Medicine article three years ago said if you had heart disease and had a certain genetic makeup, and you ate arachidonic acid, the diameter of your coronary artery was smaller, a major risk factor for a heart attack,” said Chilton. “My point is that it’s likely not worth the risk in this or other vulnerable populations.”

Chilton said tilapia is easily farmed using inexpensive corn-based feeds, which contain short chain omega-6s that the fish very efficiently convert to AA and place in their tissues. This ability to feed the fish inexpensive foods, together with their capacity to grow under almost any condition, keeps the market price for the fish so low that it is rapidly becoming a staple in low-income diets.

“We are all familiar with the classical Hippocratic admonition, Primum no nocere, ‘First, do no harm.’ I think it behooves us to consider this critical directive when making dietary prescriptions for the sake of health,” Chilton said.

“Cardiologists are telling their patients to go home and eat fish, and if the patients are poor, they’re eating tilapia. And that could translate into a dangerous situation.”

Co-authors of the study are Kelly L. Weaver, Ph.D., Priscilla Ivester, Joshua A. Chilton, Martha D. Wilson, Ph.D., and Prativa Pandey, all with Wake Forest School of Medicine. The research was funded by the National Center for Complementary and Alternative Medicine and the Office of Dietary Supplements of the National Institutes of Health (NIH), and by an NIH Molecular Medicine training grant.

Wake Forest University Baptist Medical Center (www.wfubmc.edu) is an academic health system comprised of North Carolina Baptist Hospital, Brenner Children’s Hospital, Wake Forest University Physicians, and Wake Forest University Health Sciences, which operates the university’s School of Medicine and Piedmont Triad Research Park. The system comprises 1,154 acute care, rehabilitation and long-term care beds and has been ranked as one of “America’s Best Hospitals” by U.S. News & World Report since 1993. Wake Forest Baptist is ranked 32nd in the nation by America’s Top Doctors for the number of its doctors considered best by their peers. The institution ranks in the top third in funding by the National Institutes of Health and fourth in the Southeast in revenues from its licensed intellectual property.


TOPICS: Business/Economy; Culture/Society; News/Current Events
KEYWORDS: fish; health; medical; omega3; tilapia
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To: Red Badger

Uh, yeah -that’s very interesting—pass the Tilapia.


21 posted on 07/08/2008 6:08:13 AM PDT by Carl LaFong (Building Code Under Fire)
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To: Calamari

LOL! There’s a dirt-cheap, but excellent Japanese restaurant nearby I often grab lunch at that serves squid. As a result, Calamari is the seafood I eat the most of. And I was just wondering whether I’d see any mention of Calamari here. I didn’t expect Calamari to be replying, tough!


To anyone else: I was also wondering about catfish, my favorite kind of fish. There’s passing mention of farm-raised catfish. I’d love to know whether only farm-raised is bad for you. And why was catfish only mentioned in passing? Was it simply because the study was only conducted on Tilapia, but the same issues LIKELY affect catfish eaters?


22 posted on 07/08/2008 6:08:43 AM PDT by dangus
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To: IYAS9YAS

Tilapia from China would be a horror story of antibiotics mixed with filth. At this point, I only buy US farm raised and wild caught fish.


23 posted on 07/08/2008 6:09:14 AM PDT by Varda
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To: Varda
I’ll never touch the stuff again.

Yeah, I've always heard Talapia referred to as a "trash fish". I prefer my own home grown catfish ordinarily, but the wife and I are headed for Alaska on Saturday and I plan to gorge on Salmon........

24 posted on 07/08/2008 6:09:32 AM PDT by Thermalseeker (Silence is not always a Sign of Wisdom, but Babbling is ever a Mark of Folly. - B. Franklin)
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To: Alia
Are certain Unions crabbing? Tilapia costs less than most all the other fish to purchase, currently. So more folks are probably buying Tilapia, and other "fishers" aren't getting what they want out of all this. Hmph.

Exactly the thoughts that first crossed my mind

25 posted on 07/08/2008 6:10:02 AM PDT by maine-iac7 (No trees were killed in sending this message but a large number of electrons were terrible agitated)
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To: cripplecreek
"IMO tilapia is some really nasty fish anyway."

Agreed...yet it somehow seems to always be, "the catch of the day."

I think we should feed them to all the endangered polar bears.

26 posted on 07/08/2008 6:10:46 AM PDT by Joe 6-pack (Que me amat, amet et canem meum)
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To: Calamari

Eve of destruction, tax deduction, city inspectors, bill collectors, Mod clothes in demand, population out of hand, suicide, too many bills, hippies moving to the hills. People all over the world are shouting, ‘End the war.’

And the band played on...


27 posted on 07/08/2008 6:11:18 AM PDT by Hatteras
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To: Alia
Take one look at this snip; and then read it again:

“For individuals who are eating fish as a method to control inflammatory diseases such as heart disease, it is clear from these numbers that tilapia is not a good choice,” the article says. “All other nutritional content aside, the inflammatory potential of hamburger and pork bacon is lower than the average serving of farmed tilapia.”

Anyone besides me smelling the BS meter going off the charts? Which is perhaps the Point A of the groupist MSM/Dem agenda. Meaning, meat is bad but lesser expensive fish is worse? HA. Again I say HA!

The second peg of the agenda in this article is to boon "consumers" to purchase fish they are currently NOT. Salmon Fishing is halted along the West Coast. So, what other "fishing industries" will be aided by this type of article? FDA, for example? Does it benefit by getting more agenda, thereby growing its bureacracy base?

My, my. England has a problem with its "racist foods" program.

But I see where our boobs have joined up with their boobs across the Pond.

28 posted on 07/08/2008 6:11:37 AM PDT by Alia
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To: Red Badger
Wow, and I'm fixing tilapia for supper tonight. Don't know if it's farm raised, but it probably is. It's a good thing I don't have time to get panicked about every new food scare (that, and I don't eat tilapia all that often).
29 posted on 07/08/2008 6:12:03 AM PDT by Pablo64 (What is popular is not always right. What is right is not always popular.)
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To: Red Badger

Time to sell that tilapia fish farm stock!


30 posted on 07/08/2008 6:13:35 AM PDT by Right Wing Assault ("..this administration is planning a 'Right Wing Assault' on values and ideals.." - John Kerry)
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To: Varda
“Dirty Jobs” had an episode on a fish farm. Tilapia was the fish used to eat leftovers and feces just before the water went for sewage treatment. I’ll never touch the stuff again.

I actually liked Tilapia up to that episode. These fish were fed the poop of farm raised sea bass and whatever food fed to the bass that they didn't eat. Grossed me out and put me off the stuff for good.

31 posted on 07/08/2008 6:14:35 AM PDT by pgkdan (Tolerance is the virtue of the man without convictions - G.K. Chesterton)
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To: dangus
If fish are anything like cows, the composition of their fat has to do with what they eat. Fed on grains, the fat will have low levels of Omega-3. It appears that way from the article since trout and salmon (both carnivorous fish) have better fat profiles. Herbivores seem to need no or low grain diets to achieve the same fat profile. So my guess is Yeah, wild caught should be better than farm raised.
32 posted on 07/08/2008 6:18:52 AM PDT by Varda
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To: maine-iac7
I have been watching the increased "platform" for Obama's bureacracy power growth, if elected President, being laid out by various parts of the MSM. They select what articles to cover, and just like the Al Gore/chad drama, pretend there's nothing else going on. Just like the small segment of the economy doing poorly, the MSM selects what articles it produces in order to give the appearance that the issue is an absolute across the board, total "truth".

And just like as in the Duke/Lacrosse case, it chimeras a platform that All "sports players" are racists. It yells loud. It sends its major agenda headlines to pals in other countries who then broadcast that message about "America" to foreign countries.

When in fact, what they are sending is so minute an issue about America, as to meaningless.

And therefore the MSM sends the message abroad that they "support" the "minority" position. And that said "minority position" is the truth about America.

It's a lie.

This is where the stabbings must begin -- skewering what the MSM/Dems are building towards in an eye to November, and in laying the groundwork for the 4 years after.

Stab it now.

33 posted on 07/08/2008 6:20:13 AM PDT by Alia
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To: Joe 6-pack

I like fish but tilapia is like some kind of super fish concentrate.


34 posted on 07/08/2008 6:20:53 AM PDT by cripplecreek (Voting conservative isn't for the faint of heart.)
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To: Red Badger
Well CRAP! Guess it is back... to road kill beaver for supper!
35 posted on 07/08/2008 6:21:19 AM PDT by Bender2 ("I've got a twisted sense of humor, and everything amuses me." RAH Beyond this Horizon)
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To: Red Badger

This also goes for most beef, poultry, eggs and any farmed raised fish. Switching any of these animals from their natural diet to a grain diet changes the ratio of Omega-6 to Omega-3 fatty acid in the resulting food products.

Grass fed beef, and high Omega-3 eggs and other products higher Omega-3 products are becoming more common, and are bought by consumers who desire the more natural ratio of Omega-6 and Omega-3 three in the basic foods.

And, even the higher amounts listed for farm raised salmon are still well below the amount of Omega-3 found in wild salmon.

Some speculate that the significant shift from the natural Omega-6 to Omega-3 ratios in food that occurred in the past century or so is a cause of many illnesses. Man followed a diet with a particular natural ratio for thousands of years, and the change occurred as meat and egg production shifted to large farms where grain was the major feed for the animals.


36 posted on 07/08/2008 6:22:05 AM PDT by Will88
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To: Red Badger
“All other nutritional content aside, the inflammatory potential of hamburger and pork bacon is lower than the average serving of farmed tilapia.”

OK, I'm convinced! Back to the double bacon cheeseburgers for me! Hey, who am I to argue with Science?

37 posted on 07/08/2008 6:22:12 AM PDT by cuz_it_aint_their_money ("I've played 3 presidents, 3 saints & 2 geniuses. That's probably enough for any man." C. Heston)
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To: Bender2
Well CRAP!

Are you being koi with me?.............

38 posted on 07/08/2008 6:22:47 AM PDT by Red Badger (If we drill deep enough, we can reach the Saudi oil fields from THIS side..........)
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To: pgkdan

My son and I watched that episode and the “EWWW!” factor was off the charts. We’d actually eaten the stuff the week before. No more!


39 posted on 07/08/2008 6:23:18 AM PDT by Varda
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To: Varda

“Dirty Jobs” had an episode on a fish farm. Tilapia was the fish used to eat leftovers and feces just before the water went for sewage treatment. I’ll never touch the stuff again.”

I saw the same exact episode and haven’t eaten it since.


40 posted on 07/08/2008 6:23:43 AM PDT by dellbabe68
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