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Mutant Flu Virus Is Found That Resists Popular Drug
NY Times ^ | January 31, 2008 | LAWRENCE K. ALTMAN

Posted on 02/01/2008 1:50:39 PM PST by neverdem

A small but significant percentage of the main influenza virus causing illness this winter in Europe, Canada and the United States has a mutation that makes it resistant to the anti-influenza drug Tamiflu, the World Health Organization said Wednesday.

Scientists said they were surprised by the finding because they had believed that mutations of this type generally made the virus less potent and less easily spread among people. The predominant influenza virus circulating this winter is influenza A/H1N1. The Tamiflu-resistant form of the virus, known as influenza A(H1N1 H274Y), has been found with varying frequency in various areas of four European countries, Canada and the United States.

There are no immediate plans to recommend changes in the use of Tamiflu, which is also known as oseltamivir, officials from the W.H.O. and the United States said in interviews, because the incidence of the mutant virus is still small. Tamiflu is one of the antiviral drugs used to treat influenza in its early stages.

Nevertheless, officials from the W.H.O., a United Nations agency in Geneva, said they were troubled by the discovery.

“Clearly, this is of global concern, but it is not a global problem now,” Dr. Frederick G. Hayden, an influenza expert at the organization, said in a telephone interview.

The standard influenza vaccine still protects against the mutant virus, said Dr. Hayden and Dr. Alicia Fry, an influenza epidemiologist at the Centers for Disease Control and Prevention in Atlanta.

Norwegian epidemiologists first called attention to the problem last week when they reported that the mutation was present in 12 of 16, or 75 percent, of viruses isolated in that country from patients in the earliest part of the influenza season, in November and December.

The Norwegian rate was the highest among the four European countries — Britain, Denmark, France and...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; Government; News/Current Events
KEYWORDS: health; influenzaah1n1; influenzaah1n1h274y; medicine; oseltamivir; tamiflu
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1 posted on 02/01/2008 1:50:44 PM PST by neverdem
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To: Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; Battle Axe

micro ping


2 posted on 02/01/2008 1:52:16 PM PST by neverdem (I have to hope for a brokered GOP Convention. It can't get any worse.)
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To: neverdem

I never knew Tamiflu was a popular drug. I would have guessed cocaine.


3 posted on 02/01/2008 1:58:45 PM PST by Paleo Conservative
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To: neverdem

So is this the one that is going to kill us all? Or is that EEE, West Nile, SARS, bird flu, swine flu, Hanta, dengue, Asian flu, Type A, B, X, HPV? I have an awful time keeping track of what to be deathly afraid of. I survived chicken pox, measles and mumps as a youngster but I’m wicked scared now.


4 posted on 02/01/2008 1:59:36 PM PST by Past Your Eyes (Bill Clinton: Life Member of the Liars' Club.)
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
Supercool, and Strange - Scientists are finding clues about why water is so utterly weird

FDA Alerts Health Care Providers to Risk of Suicidal Thoughts and Behavior with Antiepileptics

Premature Births Lower in Women Taking Folic Acid

FReepmail me if you want on or off my health and science ping list.

5 posted on 02/01/2008 2:00:55 PM PST by neverdem (I have to hope for a brokered GOP Convention. It can't get any worse.)
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To: Past Your Eyes
So is this the one that is going to kill us all?

No this is the drug that seasonal influenza A had not shown any appreciable resistance to prior to this flu season, IIRC.

6 posted on 02/01/2008 2:10:10 PM PST by neverdem (I have to hope for a brokered GOP Convention. It can't get any worse.)
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To: neverdem

Ruh Ro...

The Spanish flu was H1N1...


7 posted on 02/01/2008 2:14:23 PM PST by djf (...and dying in your bed, many years from now, did you donate to FR?)
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To: neverdem

Watch THIS for a description of what is IN A FLU SHOT......

http://www.youtube.com/watch?v=lxkTGqYOEDQ


8 posted on 02/01/2008 2:24:27 PM PST by goodnesswins (Being Challenged Builds Character! Being Coddled Destroys Character!)
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To: Paleo Conservative
Image and video hosting by TinyPic
9 posted on 02/01/2008 2:46:50 PM PST by billorites (I think we're all Freepers on this bus...)
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To: neverdem; AdmSmith; Berosus; Convert from ECUSA; dervish; Ernest_at_the_Beach; Fred Nerks; ...

Achoo worried at all?


10 posted on 02/02/2008 8:31:59 AM PST by SunkenCiv (https://secure.freerepublic.com/donate/__________________Profile updated Wednesday, January 16, 2008)
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

In case you missed this...ping (Thanks, neverdem!)


11 posted on 02/03/2008 12:35:10 AM PST by Smokin' Joe (How often God must weep at humans' folly.)
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To: Past Your Eyes
I have an awful time keeping track of what to be deathly afraid of.

Boogie Fever.

12 posted on 02/03/2008 12:39:33 AM PST by Grizzled Bear ("Does not play well with others.")
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To: neverdem

I had a flu shot so am I safe?


13 posted on 02/03/2008 1:51:48 AM PST by BellStar ("We recognize no Sovereign but God and no King but Jesus.")
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To: Paleo Conservative

drugs can not cure everything.....if we let our bodies have a little time, some nutrition, some rest, our bodies can actually take care of itself without endless antibiotics, antivirals, cough suppressants, decongestants, antihistamines, sleep aides, etc etc....


14 posted on 02/03/2008 2:08:53 AM PST by cherry
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To: neverdem
Bound to happen.

You kill off the non resistant bugs, the one that is resistant is left.

That, and India is having a lot of problems with bird flu right now.

15 posted on 02/03/2008 6:23:01 AM PST by redgolum ("God is dead" -- Nietzsche. "Nietzsche is dead" -- God.)
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To: Grizzled Bear

I think I’d rather have Boogie Fever than Saturday Night Fever...


16 posted on 02/03/2008 6:52:59 AM PST by null and void (Conservatism. It's the new Black...)
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To: Darksheare

Mutant flu?

We know you are behind this one somewhere!


17 posted on 02/03/2008 7:09:39 AM PST by null and void (Conservatism. It's the new Black...)
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To: null and void
I once had Rockin’ Pneumonia.
18 posted on 02/03/2008 9:24:31 AM PST by Grizzled Bear ("Does not play well with others.")
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To: null and void; Darksheare

Are you saying it’s Darksheare’s fault?


19 posted on 02/03/2008 9:25:09 AM PST by Grizzled Bear ("Does not play well with others.")
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To: Grizzled Bear; null and void
It usually is my fault.


..darn mutants gettin' loose on me. *grumble grumble*

20 posted on 02/03/2008 9:30:31 AM PST by Darksheare (Do you or anyone you know suffer from Bunny on the Head?)
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