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Synthetic chromosome developed
The Times of India ^ | 6 Oct 2007, 1536 hrs IST | PTI

Posted on 10/06/2007 5:30:52 AM PDT by CarrotAndStick

LONDON: Controversial US scientist Craig Venter claimed to have constructed a synthetic chromosome using chemicals made from the laboratory, a step towards the creation of first new artificial life form on Earth.

"This landmark will be a very important philosophical step in the history of our species. We are going from reading our genetic code to the ability to write it. That gives us the hypothetical ability to do things never contemplated before," sources reported on Saturday, quoting Venter as saying.

He is expected to announce the discovery -- a feat of bio-engineering never previously achieved -- within weeks.

According to the daily, using lab-made chemicals, Venter and his fellow researchers have painstakingly stitched together the synthetic chromosome that is 381 genes long and contains 580,000 base pairs of genetic code.

The DNA sequence is based on the bacterium Mycoplasma genitalium which the team pared down to the bare essentials needed to support life.

The chromosome has been watermarked with inks for easy recognition. It is then transplanted into a living bacterial cell and in the final stage of the process it is expected to take control of the cell and in effect become a new life form.

The scientists have already successfully transplanted the genome of one type of bacterium into the cell of another, effectively changing the cell's species.

The new life form will depend for its ability to replicate itself and metabolise on the molecular machinery of the cell into which it has been injected, and in that sense it will not be a wholly synthetic life form.

Venter said he was "100 per cent confident" the same technique would work for the artificially created chromosome. "We have carried out an ethical review before completing the experiment. We feel that this is good science."


TOPICS: Culture/Society; Extended News; News/Current Events
KEYWORDS: artificiallife; chromosome; dna; evolution; genemod; genes; geneticengineering
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To: Coyoteman; doc30; b_sharp
Like, *PING*, dudes.
21 posted on 10/06/2007 4:46:57 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: CarrotAndStick

I remember when the scientific community was all excited by the South Korean guy perfecting cloning, now we have a team that assembled its own DNA molecule and the sky is the limit. What is it with scientists wanting to play God? Pandora’s box is opened, we are off and running into the genetic age.


22 posted on 10/06/2007 7:49:48 PM PDT by Gen-X-Dad
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To: grey_whiskers

Thanks.

Venter, as usual, is on the cutting edge of anything and everything that can make him a buck.

Unfortunately for me his work is incredibly interesting. Oh well.


23 posted on 10/06/2007 8:22:07 PM PDT by b_sharp ("Science without intelligence is lame, religion without personal integrity is reprehensible"-Sealion)
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To: b_sharp
Why unfortunate for you? It distracts you from your own work?

...and I thought that Human Genome Sciences died in the dot-bomb era. Did he cash out bigtime on founder's shares?

Cheers!

24 posted on 10/06/2007 8:36:39 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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