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One Species' Genome Discovered Inside Another's
U of Rochester News ^ | 8/30/2007 | Jonathan Sherwood

Posted on 08/31/2007 7:49:29 AM PDT by TChris

Scientists at the University of Rochester and the J. Craig Venter Institute have discovered a copy of the genome of a bacterial parasite residing inside the genome of its host species.

The research, reported in today's Science, also shows that lateral gene transfer—the movement of genes between unrelated species—may happen much more frequently between bacteria and multicellular organisms than scientists previously believed, posing dramatic implications for evolution.

Such large-scale heritable gene transfers may allow species to acquire new genes and functions extremely quickly, says Jack Werren, a principal investigator of the study. If such genes provide new abilities in species that cause or transmit disease, they could provide new targets for fighting these diseases.

The results also have serious repercussions for genome-sequencing projects. Bacterial DNA is routinely discarded when scientists are assembling invertebrate genomes, yet these genes may very well be part of the organism's genome, and might even be responsible for functioning traits.

"This study establishes the widespread occurrence and high frequency of a process that we would have dismissed as science fiction until just a few years ago," says W. Ford Doolittle, Canada Research Chair in Comparative Microbial Genomics at Dalhousie University, who is not connected to the study. "This is stunning evidence for increased frequency of gene transfer."

"It didn't seem possible at first," says Werren, professor of biology at the University of Rochester and a world-leading authority on the parasite, called wolbachia. "This parasite has implanted itself inside the cells of 70 percent of the world's invertebrates, coevolving with them. And now, we've found at least one species where the parasite's entire or nearly entire genome has been absorbed and integrated into the host's. The host's genes actually hold the coding information for a completely separate species."

(Excerpt) Read more at rochester.edu ...


TOPICS: Miscellaneous; US: New York
KEYWORDS: genetics; science
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That's just freaky. It's the stuff of sci-fi / horror movies.
1 posted on 08/31/2007 7:49:33 AM PDT by TChris
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To: TChris

Pretty cool. Why would an organism need a copy of another in its DNA unless it was to synthesize it at some point? Kind of a weird way to accomplish reproduction.


2 posted on 08/31/2007 8:08:40 AM PDT by billybudd
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To: TChris
Scientists at the University of Rochester and the J. Craig Venter Institute have discovered a copy of the genome of a bacterial parasite residing inside the genome of its host species.

Wait until the RIAA hears about this - no species on Earth will be safe from their lawyers and lawsuits...

3 posted on 08/31/2007 8:08:55 AM PDT by The Electrician ("Government is the only enterprise in the world which expands in size when its failures increase.")
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To: TChris
It's happened before:


4 posted on 08/31/2007 8:09:56 AM PDT by ElkGroveDan (When toilet paper is a luxury, you have achieved communism.)
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To: ElkGroveDan; NormsRevenge; SunkenCiv

ROFL!


5 posted on 08/31/2007 8:11:03 AM PDT by Ernest_at_the_Beach (No Burkas for my Granddaughters!!!)
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To: TChris

I believe it. I’ve known people that are pond scum.


6 posted on 08/31/2007 8:11:35 AM PDT by Moonman62 (The issue of whether cheap labor makes America great should have been settled by the Civil War.)
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To: All
Wolbachia may be the most prolific parasite in the world—a "pandemic," as Werren calls it. The bacterium invades a member of a species, most often an insect, and eventually makes its way into the host's eggs or sperm. Once there, the wolbachia is ensured passage to the next generation of its host, and any genetic exchanges between it and the host also are much more likely to be passed on.
7 posted on 08/31/2007 8:13:27 AM PDT by Ernest_at_the_Beach (No Burkas for my Granddaughters!!!)
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To: TChris

bttt


8 posted on 08/31/2007 8:19:06 AM PDT by facedown (Armed in the Heartland)
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To: TChris

Where do you suppose viruses and other cold germs go when they take up residence in your body? That’s right, they get jobs and don’t bother with Green Cards. Most of the otherwise meaningless DNA in our cells is these illegals.


9 posted on 08/31/2007 8:21:32 AM PDT by RightWhale (It's Brecht's donkey, not mine)
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To: TChris

I don’t think we fully understand this DNA thing yet.


10 posted on 08/31/2007 8:28:29 AM PDT by blam (Secure the border and enforce the law)
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To: TChris
"Using recombinant DNA technology, Harold inserted what he hoped was the DNA for superhuman powers into a harmless bacterium. Crossing his fingers and holding his nose, he raised the test tube to his lips after repeating his prayer to fly like superman. His lab bench was covered with the tiny bodies of the houseflies from which he pulled the flight genes, or so he hoped. What could possibly go wrong, he thought as the liquid touched his tongue ..."
11 posted on 08/31/2007 8:32:33 AM PDT by NonValueAdded (Brian J. Marotta, 68-69TonkinGulfYachtClub, (1948-2007) Rest In Peace, our FRiend)
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To: TChris

Does this mean that finding similarities in genes in different
organisms doesn’t have to mean that the organisms are related
in any evolutionary fashion?
Does wolbachia only parasitize bacteria? Do more complex
organisms like the fungi have the wolbachia genome?
How does the host bacteria coexist? How and why did the wolbachia
develop this technique in the first place? If genes are
“selfish” why does the Wolbachia coexist?
Should people emulate the host, and allow coexistence, or
should people emulate Wolbachia and parasitize the host,
or should what we emulate and accept what “naturally” occurs?
Complex life is, no?


12 posted on 08/31/2007 8:33:17 AM PDT by Getready (Truth and wisdom are more elusive, and valuable, than gold and diamonds)
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To: TChris

I have a hypothesis that “jumping genes” carried by viruses or bacteria drive a lot of evolution. For example, when ice ages came along, a lot of fauna (mammoths, mastodons, bison, rhinos, etc.) suddenly developed fuzzy undercoats with long guardhair outcoats. Could the gene that carries that particular survival trait have jumped multiple species? I think that is more likely than having such a survival trait simultaneously appear by mutation in multiple species. “Jumping genes” could also explain how genetic and species variation could proceed at a much faster pace than with random mutation. Whole segments of DNA and RNA could suddenly appear in a different species. Sort of like inserting an entire subroutine of code into an existing computer program instead of a random 0 or 1.


13 posted on 08/31/2007 8:42:09 AM PDT by darth
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To: TChris
"The question is, are these foreign genes providing new functions for the host? This is something we need to figure out."

Hmm...

Wolbachia, in the organic world, acts similar to a function in the computer world. When you add a function or a module or an object to another object or program, it either enhances or detracts from the original object or program.

What a design!
14 posted on 08/31/2007 8:48:20 AM PDT by adorno
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To: darth

Jumpin’ Genomes!


15 posted on 08/31/2007 9:14:22 AM PDT by onedoug
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To: TChris; AndrewC; js1138

A functioning DNA process that deliberately inserts itself into a different species is evidence of intelligent intervention.

It’s not Evolution in any way, shape, or form.


16 posted on 08/31/2007 9:19:40 AM PDT by Southack (Media Bias means that Castro won't be punished for Cuban war crimes against Black Angolans in Africa)
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To: Southack
It’s not Evolution in any way, shape, or form.

You underestimate modern evolutionists, FRiend. If a scientist can but imagine how evolution might be able to explain it, then they're still good to go.

Evidence is so passé.

17 posted on 08/31/2007 9:25:04 AM PDT by TChris (Has anyone under Mitt Romney's leadership ever been worse off because he is Mormon?)
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To: RightWhale

Only a selective set of viruses attach to or mutate DNA.


18 posted on 08/31/2007 9:50:03 AM PDT by PissAndVinegar
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To: Southack

It’s neither, it’s simple self preservation.

Parasites, viruses and various symbiotic organisms have been doing it for millennium.


19 posted on 08/31/2007 9:52:36 AM PDT by PissAndVinegar
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To: TChris

This is exactly what is happening to Morgellons patients, however, I cannot say more on the subject.


20 posted on 08/31/2007 9:53:08 AM PDT by Scythian
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