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Too fat? Common virus may be to blame: study
Reuters ^ | 08/20/2007 | Julie Steenhuysen

Posted on 08/20/2007 1:44:54 PM PDT by Responsibility2nd

CHICAGO (Reuters) - A common virus caused human adult stem cells to turn into fat cells and could explain why some people become obese, U.S. researchers said on Monday.

The research builds on prior studies of adenovirus-36 -- a common cause of respiratory and eye infections -- and it may lead to an obesity vaccine, they said.

"We're not talking about preventing all types of obesity, but if it is caused by this virus in humans, we want a vaccine to prevent this," said Nikhil Dhurandhar, an associate professor at Pennington Biomedical Research Center at Louisiana State University System.

The virus adenovirus-36 or Ad-36, caused animals to pack on the pounds in lab experiments. "These animals accumulated a lot of fat," Dhurandhar said in a telephone interview.

Dhurandhar also has shown that obese people were three times more likely to have been infected with Ad-36 than thin people in a large study of humans.

Now, researchers in Dhurandhar's lab have shown that exposure to the virus caused adult human stem cells to turn into fat-storing cells.

Dr. Magdalena Pasarica, who led the study, obtained adult stem cells from fat tissue of people who had undergone liposuction. Stem cells are a type of master cell that exist in an immature form and give rise to more specialized cells.

Half of the stem cells were exposed to the virus Ad-36. After a week, most of the infected stem cells developed into fat cells, while the uninfected cells were unchanged.

Pasarica presented her findings at a meeting of the American Chemical Society in Boston.

"The virus appears to change their commitment to a fat storing cell," Dhurandhar said, adding that Ad-36 is just one of 10 pathogens linked to obesity and that more may be out there.

He acknowledged that some people might find it hard to believe that a virus could be responsible for obesity.

"Certainly overeating has something to do with gaining weight. No doubt about that. But that is not the whole truth," Dhurandhar said. "There are multiple causes of obesity. They range from simple overeating to genes to metabolism and perhaps viruses and infections."

Long term, he said he hoped to develop a vaccine and perhaps treatments for the virus. But first, he and colleagues need to better understand the role of Ad-36 in human obesity, he said.

Globally, around 400 million people are obese, including 20 million children under age 5, according to the World Health Organization.


TOPICS: Miscellaneous; News/Current Events
KEYWORDS: ad36; adenovirus36; adultstemcells; diet; health; obesity; stemcells; tr
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To: Responsibility2nd

It’s more likely an effect rather than a cause. A fat persons body is highly acidic, full of candida and yeast, and low in oxygen, this is the perfect environment for such stuff to exist.


181 posted on 08/21/2007 8:38:53 AM PDT by Scythian
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To: gopheraj

wow...that is a ton of stress...glad to hear you are doing better now.....thanks again for all the info...I’ve passed it on to her


182 posted on 08/21/2007 8:52:39 AM PDT by superfries
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To: Wonder Warthog

super info..thanks for the follow-up!


183 posted on 08/21/2007 8:53:06 AM PDT by superfries
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To: SirJohnBarleycorn

Thanks for the link....we will have to give this a try...


184 posted on 08/21/2007 8:53:44 AM PDT by superfries
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To: superfries
Sauteed shrimp at your favorite seafood restaurant (or your own kitchen) is one example of good cholesterol. Have peek at this book at your local bookstore. Lots of good, sensible advice inside.

You can get a quick preview from Schwarzbein's website here.

185 posted on 08/21/2007 9:50:54 AM PDT by Myrddin
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To: superfries

Yeah thanks. Much better. My sypmtoms that sent me to the doc were not weight (although I was POed about that) Mine was brain fog, no memory, not being able to stay focused, NO sex drive (and this was a biggie for me) I really thought I was getting alzheimers. Went to the doc two years ago for the symptoms, she gave me zoloft. All that did was help my sleep and add some pounds. Gave it up after a year. This year, after getting progressively worse on the brain stuff, went back to her and be damned if she didn’t want to give me zoloft again. Got really close to my face and said that my symptoms were also hormonal/menopausal something I went through 7 years before so I KNEW what that was. It realy pissed me off for her to say that - like I don’t know what is going on with my own body. Anyway, after tests results and a scan of my thyroid, why, yes I do have a problem. I wasn’t depressed but after going to the doc I was getting that way. LOLL After a bunch of that stuff happened, we joked that we would have been alcolohics but couldn’t afford the likker LOLL


186 posted on 08/21/2007 9:54:53 AM PDT by gopheraj
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To: Paved Paradise

That may be so but I’d like to know how you know that.

Check out Robert Ardrey’s book titled African Genesis.

Hunting is not that easy. Try it sometime and you’ll see what I mean.

I hunt. My first gun (besides the usual .22 was a .300 Wby built by Jesse Harpe’s gunsmith Herb back in the mists of time when I was in the 9th grade.

Also, their tools were primitive.

So is a bow.

And they didn’t live long either, so if they did eat that kind of diet, maybe that’s another reason they all kicked off so young.

Whacking lions and leopards on the head is inherently risky.

Also, if this is true, I don’t really care what prehistoric man ate. I’d like to keep at least within the past few hundred years for sanity’s sake.

Consider how much genetic change can occur and become widespread amongst humans in a mere few hundred years.


187 posted on 08/21/2007 10:44:22 AM PDT by GladesGuru (In a society predicated upon freedom, it is essential to examine principle)
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To: Paved Paradise
I actually have done quite a bit of study on this

Bull.

Don't bother replying, I see the other posts in this thread and can see you're a fundamentalist true believer in the "all fat people are lazy" crowd.
188 posted on 08/21/2007 10:51:35 AM PDT by dan1123 (You are to be perfect, as your heavenly Father is perfect. --Jesus)
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To: Paved Paradise
I will grant you that many factors go into long life, but let’s face it, we have some control over our fate and being heavy is normally not a route to longevity

I actually agree. Obesity is hard on the body.

I think the biggest hurdle for people trying to lose weight (and/or just stay healthy) is that we don't really know how to eat well anymore. A lot of the products on the shelf are little more than processed junk and that includes some or even most of what's being passed off as health food. Also, people tend to forget that not all calories are the same. There's something to be said for the nutritional content, or lack thereof, in any given product. But I think good nutrition is far more complicated than what gets printed on the side of a box.

Ironically, the processed food industry was born (at least partly) out of a concern for healthy eating. Working women needed a way to feed their kids something decent. Obviously, they didn't have a lot of time left to spend in the kitchen. Processed food was the solution. This has become a very large industry. But somewhere along the way it's become more about money and less about health, as evidenced by all the trash being marketed as food.

189 posted on 08/21/2007 10:56:53 AM PDT by monkfan
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To: El Gato

Yep, we’ve got to keep watching out for stuff that hit our families, which is cancer for mine. Good idea to keep watching that bowel, and colon. Your wife’s grandmother probably got thinner because she ate so little. They probably had to fight to get her to eat. That isn’t life. It is existing.

Take care.


190 posted on 08/21/2007 2:18:08 PM PDT by oneamericanvoice (Support freedom! Support the troops! Surrender is not an option!)
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To: discostu
Well one of the reasons there’s no cure for the common cold is that it actually doesn’t exist, it’s actually a couple dozen different interrelated viruses that interbreed recombine and mutate constantly. Same reason we can’t cure the flu

You'll note that this one is described as "adenovirus-36 -- a common cause of respiratory and eye infections". Sounds like a cold or flu virus to me. But what do I know, so I checked the CDC website and found this:

Adenoviruses most commonly cause respiratory illness; however, depending on the infecting serotype, they may also cause various other illnesses, such as gastroenteritis, conjunctivitis, cystitis, and rash illness. Adenoviruses most commonly cause respiratory illness; however, depending on the infecting serotype, they may also cause various other illnesses, such as gastroenteritis, conjunctivitis, cystitis, and rash illness. Symptoms of respiratory illness caused by adenovirus infection range from the common cold syndrome to pneumonia, croup, and bronchitis.

Treatment: Most infections are mild and require no therapy or only symptomatic treatment. Because there is no virus-specific therapy, serious adenovirus illness can be managed only by treating symptoms and complications of the infection.

Prevention: Vaccines were developed for adenovirus serotypes 4 and 7, but were available only for preventing ARD among military recruits. Strict attention to good infection-control practices is effective for stopping nosocomial outbreaks of adenovirus-associated disease, such as epidemic keratoconjunctivitis. Maintaining adequate levels of chlorination is necessary for preventing swimming pool-associated outbreaks of adenovirus conjunctivitis

191 posted on 08/21/2007 5:26:11 PM PDT by El Gato ("The Second Amendment is the RESET button of the United States Constitution." -- Doug McKay)
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To: oneamericanvoice
Your wife’s grandmother probably got thinner because she ate so little. They probably had to fight to get her to eat. That isn’t life. It is existing.

Well, that's probably true, but she never got all that thin, just thinner. I think she just forgot to eat, like she forgot to change her clothes, do her housework (she had been fastidious in both areas) and eventually forgot to recognize her family, even including her husband.

192 posted on 08/21/2007 5:28:36 PM PDT by El Gato ("The Second Amendment is the RESET button of the United States Constitution." -- Doug McKay)
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To: El Gato

That is sooo sad. I’m sorry for you, your family, and your grandmother.


193 posted on 08/21/2007 5:31:34 PM PDT by oneamericanvoice (Support freedom! Support the troops! Surrender is not an option!)
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