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Happy 150th birthday: a new era looms for old age
Reuters ^ | Mar 15, 2006 | Ben Hirschler

Posted on 03/16/2006 7:51:36 AM PST by djf

OXFORD (Reuters) - Modern medicine is redefining old age and may soon allow people to live regularly beyond the current upper limit of 120 years, experts said on Wednesday.

It used to be thought there was some inbuilt limit on lifespan, but a group of scientists meeting at Oxford University for a conference on life extension and enhancement dismissed that idea.

Paul Hodge, director of the Harvard Generations Policy Program, said governments around the world - struggling with pension crises, graying workforces and rising healthcare costs - had to face up to the challenge now.

"Life expectancy is going to grow significantly, and current policies are going to be proven totally inadequate," he predicted.

Just how far and fast life expectancy will increase is open to debate, but the direction and the accelerating trend is clear.

Richard Miller of the Michigan University Medical School said tests on mice and rats - genetically very similar to humans - showed lifespan could be extended by 40 percent, simply by limiting calorie consumption.

Translated into humans, that would mean average life expectancy in rich countries rising from near 80 to 112 years, with many individuals living a lot longer.

Aubrey de Grey, a biomedical gerontologist from Cambridge University, goes much further. He believes the first person to live to 1,000 has already been born and told the meeting that periodic repairs to the body using stem cells, gene therapy and other techniques could eventually stop the aging process entirely.

De Grey argues that if each repair lasts 30 or 40 years, science will advance enough by the next "service" date that death can be put off indefinitely - a process he calls strategies for engineered negligible senescence.

His maverick ideas are dismissed by others in the field, such as Tom Kirkwood, director of Newcastle University's Center of Aging and Nutrition, as little more than a thought experiment.

Kirkwood said the human aging process was intrinsically malleable - meaning life expectancy was not set in stone - but researchers had only scratched the surface in understanding how it worked.

CALL FOR FUNDING

The real goal is not simply longer life but longer healthy life, something that is starting to happen as today's over-70s lead far more active lives than previous generations.

Jay Olshansky of the University of Illinois in Chicago is confident that longevity and health will go hand in hand and that delaying aging will translate into later onset for diseases like cancer, Alzheimer's and heart disease.

But to get to the bottom of understanding the biology of aging will require a major step-up in investment.

Olshansky and his colleagues have called on the U.S. government to inject $3 billion a year into the field, arguing the benefits of achieving an average seven-year delay in the process of biological aging would far exceed the gains from eliminating cancer.

Ethically, the extension of life is controversial, with some philosophers arguing it goes against fundamental human nature.

But John Harris, Professor of Bioethics at the University of Manchester, said any society that applauded the saving of life had a duty to embrace regenerative medicine.

"Life saving is just death postponing with a positive spin," he said. "If it is right and good to postpone death for a short time, it is hard to see now it would be less right and less good to postpone it for a long while."


TOPICS: Culture/Society; Miscellaneous; News/Current Events
KEYWORDS: aging; geezers; longevity
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To: AnotherUnixGeek

You really believe that there are enough jobs, to support all those people from 20yo to 80yo?


41 posted on 03/16/2006 9:56:06 AM PST by stuartcr (Everything happens as God wants it to.....otherwise, things would be different.)
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To: djf
As the problems with these systems from an aging perspective are figured out, the limits on aging will be drastically pushed... I mean very, very drastically.

Exactly. It's not about adding to the end of your life, but the middle. Not hanging on for 20 more years in a nursing home, but maintaining the physical health of a 25-year old indefinitely.

Concerns about Social Security and retirement are silly. If this happens, permanent retirement goes away completely because people won't become physically unable to work. Instead you could work for 40 years, take a few years off for an extended vacation, repeat as long as you want. Sign me up.

42 posted on 03/16/2006 10:00:57 AM PST by ThinkDifferent (Chloe rocks)
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To: stuartcr
You really believe that there are enough jobs, to support all those people from 20yo to 80yo?

Sure. The quantity of jobs is not fixed. Half of Americans were farmers not that long ago.

43 posted on 03/16/2006 10:02:46 AM PST by ThinkDifferent (Chloe rocks)
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To: djf

You'd either have to save like a som a buck in your early years or else work till you are 130.

No thankx


44 posted on 03/16/2006 10:06:20 AM PST by TASMANIANRED (The Internet is the samizdat of liberty..)
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To: stuartcr
You really believe that there are enough jobs, to support all those people from 20yo to 80yo?

If the economy were to grow, yes.

But growing economies aren't the issue, shrinking economies are.

Populations in Western Europe are heading for a decline. The US population would be heading the same way if not for immigration, both legal and illegal. The rate of population increase in both China and India is slowing, and will eventually reverse later in the century as both nations develop - people in developed nations don't want or need as many children. Economies will inevitably shrink as workers retire unreplaced and their jobs disappear. Japan seems headed down this road right now.

One solution for this, and a way to prevent a shrinking percentage of workers supporting a growing percentage of retirees, is to keep people healthy enough to work longer and to want to work longer.
45 posted on 03/16/2006 10:07:24 AM PST by AnotherUnixGeek
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To: ThinkDifferent

Problem is, from most of what I've read in the abstracts, etc. if you wait till you're 40 or 50, you've waited too long.

Over and over you read things like "the bodies production of enzyme X falls off dramatically after age 30 or so"... and the like.

I imagine most things are reversible, but of those that aren't, some would be killers.


46 posted on 03/16/2006 10:09:06 AM PST by djf (I'm not Islamophobic. But I am bombophobic! If that's the same, freakin deal with it!)
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Comment #47 Removed by Moderator

To: djf

My mom is 84 years old, just a few gray hairs, reads without glasses, very healthy, though getting bored with life. She still cleans her own house and cooks her own meals. She takes no prescription medication but is religious about her vitamin pills. My dad was the opposite of this and died at 68 years old after heart surgery.


48 posted on 03/16/2006 10:16:34 AM PST by MontanaBeth (Never under estimate the enemy.)
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